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Biomedical subjects

J M Mehta

Publications and source records attributed to J M Mehta.

At least 37 records · Page 2Linked to original sources
PubMed1983

Special features of physical therapy in the claw hand of leprosy.

This article emphasizes the vital role of a physical therapist in the surgical programme of the correction of clawing caused in leprosy due to paralysis of intrinsics. Right from the assessment of patient till the final re-education a physical therapist is a must helping in motivating the patient, planning the type of procedure to be performed on him and training the patient post-operatively. If treated early a physical therapist himself can overcome the deformity by the help of various physical therapy measures without surgical intervention.

Hand Deformities, Acquired↗
PubMed1983

Effect of levamisole on clinical outcome and DNCB conversion in leprosy patients. A long term study.

Fifteen patients of lepromatous leprosy within first 6 months of diagnosis were studied. 7 controls received standard DDS treatment and placebo while 8 patients received cyclical levamisole treatment (150 mg daily for 3 days repeated after a gap of 2 weeks), in addition to standard DDS treatment. Patients were followed up clinically for lepra reactions, serial B.I. and DNCB test for 2 years. We observed that ENL reactions were more common and more severe in levamisole treated group while an upgrading type reaction occurred only in one of the control patients. B I. remained same in both groups throughout, while DNCB score was higher in control rather than levamisole treated groups. Thus, levamisole treatment does not seem to have caused stimulation of CMI in our patients as judged by DNCB reaction while it may have caused stimulation of humoral immunity as seen by higher incidence of ENL reaction. This may be undesirable in lepromatous patients.

Dapsone↗
PubMed1982

Observations on peg-prosthesis in leprosy.

Three leprosy patients with peg-prosthesis were studied in detail. It was found that there were several disadvantages of this type of prosthesis. However, its application in a rural situation has some merits, and with some suggested modifications, it could be adopted with better results.

Artificial Limbs↗
PubMed1979

A new approach in the relief of pain of leprous neuritis.

Transcutaneous Nerve Stimulation (TNS) has been known since the last several decades to relieve pain in many conditions. For the first time it was used in the treatment of the severe and agonizing pain caused by leprous neuritis with highly beneficial results without producing any side effects. This study was made on 40 patients, and in the majority of the cases there was total relief of pain with one application of a few hours duration. This encouraging result has led the authors to the conclusion that TNS could be a useful tool in a hospital where leprosy patients are treated.

Central Nervous System↗
PubMed1976

Urate crystal-induced chemotactic factor: isolation and partial characterization.

A factor with chemotactic properties for neutrophils and mononuclear cells was extracted from the lysosomal fraction of both human and rabbit neutrophils that had been allowed to phagocytose monosodium urate crystals. The chemotactic factor was found to be a glycoprotein with a mol wt of 8,400 daltons. The factor is heat labile and has chemotactic activity for human as well as rabbit cells. Preincubation of the cells with the urate induced chemotactic factor or with complement activated plasma prevents the cell from migrating chemotactically when challenged with either factor in the chemotactic chamber. The chemotactic factor induces release of lysosomal enzymes for cytochalasin B treated human neutrophils.

Glucuronidase↗