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Biomedical subjects

J M MacGregor

Publications and source records attributed to J M MacGregor.

8 recordsLinked to original sources

Introduction of an endocardial pacing lead through the costocervical vein in six dogs.

Lead dislodgement is one of the most common complications of endocardial pacing lead implantation in dogs. Incidence of lead displacement appears to be higher in large-breed, compared with small-breed, dogs, suggesting that excessive neck movements may be a contributing factor. To avoid introducing pacing leads through a vein in the neck, we developed a technique for implantation of endocardial pacing leads through the right costocervical vein. A right second intercostal space thoracotomy was performed to expose the vein, and the pacing generator was placed in the musculature over the lateral aspect of the thorax. The technique was performed in 6 dogs, 5 of which had had an endocardial pacing lead dislodge. None of the dogs had problems with lead dislodgement during follow-up periods of 15 to 20 months. Implantation of endocardial pacing leads through the costocervical vein should not be considered a replacement for implantation through the jugular vein. However, we believe that this technique is indicated for large dogs in which endocardial pacing leads implanted through the jugular vein have dislodged.

Animals

The prevalence of Huntington's chorea in South Africa.

The results of a national investigation to determine the prevalence of Huntington's chorea in South Africa are presented. A total of 481 persons who have died from or are presently suffering from the disorder have been identified. The prevalence rate of 0,1 per million in the South African Negro population is much less than the estimate of 22 per million in the White and Coloured groups. It is apparent that the great variation in the ethnic distribution of the disease is a reflection of the diverse origins of the different population groups of South Africa.

Black People