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Biomedical subjects

J M Leach

Publications and source records attributed to J M Leach.

6 recordsLinked to original sources

A simple computer method for processing pathology data.

A simplified computer method for recording postmortem and histopathological findings is described. The method allows a major reduction in the workload of the pathologist and provides a convient means of selection and comparison of experimental results.

Computers

A latex agglutination test for hepatitis type B antigen.

A new latex agglutination test system (ANTIGEX-TM) for the detection of Hepatitis B Antigen (HBAg) is described. It can be used to detect HBAg in either serum or plasma with a sensitivity comparable to that of complement fixation and about four times greater than counterimmunoelectrophoresis. The sensitivity and specificity of the system is illustrated by the test results obtained on the F.D.A. Bureau of Biologics Sera Panel No. 2 and on sera and plasma specimens from normal blood donors in the U.K. and the USA. Further applications of the technique, in the detection of HBAg in finger-prick blood samples, and in the rapid determination of antigen subtype ('ad' or 'ay'), are also described.

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