Search PubMed⌕ Search

Biomedical subjects

J M Jimenez

Publications and source records attributed to J M Jimenez.

29 records · Page 2Linked to original sources
PubMed1976

Concurrent use of prostaglandin F2alpha and laminaria tents for induction of midtrimester abortion.

One hundred sixteen women between 14 and 20 weeks of gestation were aborted with a combined regimen of intraamniotic prostaglandin F2alpha (PGF2alpha) and intracervical laminaria. Complications among these women were compared to those among 122 patients who aborted after PGF2alpha administration only. Shorter intervals between initiation and completion of abortion were observed in nulliparous women treated with the combined regimen than in nulliparous women treated with PGF2alpha only. In parous patients, the use of laminaria did not shorten the interval from initiation to completion of abortion. A decrease of the hematocrit in excess of 5 points and periabortal infection requiring antibiotic therapy occurred with similar frequency in both treatment groups. However, with the combined regimen no cervical tears were observed in nulliparous patients, and fewer women failed to abort within 48 hours.

Abortion, Induced↗
PubMed1975

Pregnancy performance of patients under fifteen years of age.

Pregnancy performance of 471 patients under age 15 who delivered between 1968 and 1972 was compared with that of the same number of control patients between 19 and 25 years of age. The control group was selected by the paired method technic, whereby each study patient was paired with a control patients utilizing identical race and contribution to hospital cost as the economic determinant. The results of the study showed that young patients differed significantly from the control group in having an earlier menarche and a greater number of recurring pregnancies within 18 months of the initial one. Pregnancy-induced hypertension and pelvic inlet contraction were pregnancy complications occurring more frequently among study patients than control patients.

Adolescent↗
PubMed1975

Phospholipid biosynthesis: the activity of phosphatidic acid phosphohydrolase in the developing lung and amnionic fluid.

The presented data suggest that PAPase may, indeed, be important in the biosynthesis of lung phospholipids. The observed increase in the specific activity of rabbit lung precedes the "surge" of phosphatidylcholine concentration and surfactant biosynthesis by at least 24 hours. In human amnionic fluid, PAPase specific activity was markedly increased in pregnancies of 35 weeks of gestation or more. The increase in the specific activity of PAPase preceded the "surge" of acetone precipitated phosphatidylcholine. The reported studies may provide an additional procedure to examine the problems associated with surfactant biosynthesis.

Amniotic Fluid↗
PubMed1975

Fetal lung maturatio. III. Amniotic fluid phosphatidic acid phosphohydrolase (PAPase) and its relation to the lecithin/sphingomyelin ratio.

The purpose of this study was to establish 1) the sequential changes in specific activity of phosphatidic acid phosphohydrolase (PAPase) in amniotic fluid and its relation to the lecithin/sphingomyelin (L/S) ratio; and 2) the origin of amniotic fluid PAPase. the increase in the amniotic fluid L/S ratio is preceded by an increase in PAPase activity, rising from 15 nmoles of phosphate released per milligram of protein per hour at 30 weeks to 100 nmoles at 37 weeks. The mean PAPase activity in the nasopharyngeal fluid of the infant is 456 nmoles of phosphate released per ml per hour, the amniotic fluid mean PAPase activity at delivery being 129 nmoles (P less than 0.01). These findings are consistent with the view that amniotic fluid PAPase originates, in part, from the fetal lung and likely participates in the regulation of the synthesis of lecithin.

Amniotic Fluid↗