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Biomedical subjects

J M Jacobson

Publications and source records attributed to J M Jacobson.

53 records · Page 3Linked to original sources
PubMed1984

Changes in thyroid function and serum iodine levels after prepartum use of a povidone-iodine vaginal lubricant.

To determine if application of iodide to vaginal mucosa of pregnant women results in significant iodide absorption or changes in thyroid function, we studied 18 intrapartum women for whose examinations during labor povidone-iodine gel was used as a lubricant and 16 for whose examinations an iodine-free lubricant was used. Both serum inorganic iodine and total serum iodine increased significantly (p less than 0.001) after iodide exposure and fell (p = 0.003) to near baseline within two days. In both groups, serum thyroxine and triiodothyronine fell during labor and delivery; differences between groups were not significant. In the iodine-treated group, however, there was a significant increase in thyroid-stimulating hormone at two days postpartum (p less than 0.001). Iodide applied to vaginal mucosa of pregnant women is absorbed and affects the maternal pituitary-thyroid axis.

Administration, Topical↗
PubMed1982

Necrotizing fasciitis complicating intravenous drug abuse.

Two cases of necrotizing fasciitis in intravenous cocaine abusers are presented to alert the medical community to the possibility of these severe infections in such addicts. Antimicrobial therapy should include agents effective against Bacteroides species, streptococci, and Gram-negative aerobes; therapy directed only against staphylococci and Gram-negative aerobes is not sufficient.

Adult↗
PubMed1979

Alcohol-induced Cushingoid syndrome.

A 35-year-old woman with alcoholic liver disease presented with physical stigmas and laboratory confirmation of Cushing's syndrome. With discontinuance of alcohol, her signs of Cushing's syndrome resolved and the urinary free cortisol and the urinary 17-hydroxycorticosteroid response to dexamethasone returned to normal. These findings broaden the spectrum of deranged glucocorticoid chemistry that can occur in alcohol-induced cushingoid syndrome.

Adult↗
PubMed1969

Switching requirements in a Head Start classroom.

Two experiments were conducted by the mothers of the children in a Head Start classroom. Both examined the effects of a switching task on the frequency with which children moved from one activity area of the classroom to another. The results indicated that the rate at which the children changed activities could be adjusted by varying the difficulty or magnitude of the switching task and that the task itself could be used to introduce academic subjects which would be poorly attended if initially presented in an activity area.

Journal Article↗
PubMedDate not supplied

Maximizing life's potentials in AIDS: a psychopharmacologic update.

Psychiatric factors play a major role in the AIDS pandemic. They have an impact on transmission, morbidity, coping, adherence, and quality of life and of death. Substance-related disorders are associated with HIV transmission through needle sharing, sexual transmission, exchange of sex for drugs, and perinatal transmission. Persons with AIDS have a high prevalence of substance-related disorders, mood disorders, dementia, mania, and delirium. Persons with AIDS require complex medications, including combination antiretroviral therapy and prophylaxis and treatment for opportunistic infections and cancers. Recognition and treatment of distressing symptoms can maximize life's potentials and enhance adherence with risk prevention and with care. We describe an integrated approach to the use of psychotropic medications in the care of persons with AIDS. With the new antiretroviral therapies available, psychotropic medications can be helpful in alleviating distressing symptoms, promoting less risk taking, and adhering to complex medical care. The intricacies and complexities of new medical and psychopharmacological issues are delineated in order to enable caregivers help persons with AIDS to maximize life's potentials.

AIDS Dementia Complex↗
PubMedDate not supplied

Midlife Baby Boom women compared with their older counterparts in midlife.

A stratified random sample of midlife Baby Boom women, ages 35-42, was compared with a group of older midlife women, ages 43-55. The sample consisted of 992 women who had graduated between the years of 1955 and 1975 from a large university in southern California. Measures of anxiety and life satisfaction were administered to each year group. This served to control for the effect of age and was helpful in explaining whether the differences between the groups were age related or the result of socialization. The Baby Boom cohort of women, born after January 1, 1946, have only recently entered the ranks of midlife. They have been recognized as unique and less traditional than their older counterparts with regard to sexual freedom, career choices, and educational opportunities. Similarities and differences were found between the two groups of women. However, the results clearly revealed that the effects of socialization, rather than age, yielded the major significant variables influencing a feeling of well-being in both cohorts of midlife women.

Adult↗
PubMedDate not supplied

The relationship between social support and depression in adolescents.

In a non-clinical, adolescent sample, this correlational study tested the hypothesis that there will be an inverse correlation between perceived social support and depression. This hypothesis is consistent with the theoretical literature. The results suggest that perceived social support is associated with depression in adolescents.

Adolescent↗
PubMedDate not supplied

Stressful life events and accidents at school.

High school is a time of stress for most adolescents. School nurses need to be aware of the high levels of stress and the potential relationship stress has to accidental injury in order to plan better preventive care along with teachers, counselors, and coaches.

Accident Prevention↗