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Biomedical subjects

J M Hay

Publications and source records attributed to J M Hay.

At least 127 records · Page 7Linked to original sources
PubMed1983

[Surveillance of patients operated on for cancer of the stomach].

Recurrence following curative excision of gastric cancer occurs in 9 cases out of 10 during the 5 years following surgery. Repeat operations are of benefit in 20 p. cent of cases of recurrence, and postoperative follow-up surveillance of these patients should be routinely conducted for at least 5 years. As the recurrence level is highest during the first 2 years, examinations are probably necessary every 4 months during this period, followed by yearly examinations up to the end of the fifth year. Complementary investigations include biological tests and morphology.

Adenocarcinoma↗
PubMed1981

[Acute abdominal pain syndrome. The computer as an aid to diagnosis (author's transl)].

With a bank of data collected locally and a probability program of diagnostic aid, the computer is capable of making the correct diagnosis in 79% of acute abdominal pain syndromes. Its performance in this respect is somewhat superior to that of clinicians (73.5%). Including a computer program in diagnostic procedures would reduce the number of errors by excess or omission. In abdominal emergencies computerization would help either by increasing the reliability of clinical diagnoses or by suggesting that other possibilities should be investigated.

Abdomen, Acute↗
PubMed1981

[Pharmacokinetic study of flubendazole in human hydatid disease caused by Echinococcus granulosus. Preliminary results (author's transl)].

A pharmacokinetic study of flubendazole was carried out, using a radioimmunological method, in patients with hydatid disease about to undergo surgery; there was no evidence of drug penetration into the walls or contents of the cysts. Another study, carried out simultaneously in subjects without hydatid disease, showed very high concentrations of the drug in liver tissue and in bile. These results should not be taken as arguments against the effectiveness of flubendazole, but should encourage the setting up of further randomized pharmacokinetic studies.

Adult↗
PubMed1981

[Radiation-induced intestinal lesions. Prognosis and surgical management (author's transl)].

Thirteen patients with intestinal lesions consecutive to radiotherapy for carcinoma of the uterus were operated upon between 1973 and 1979. The small bowel was involved in 9 patients and the colon and rectum in 4 patients. Urinary tract lesions were associated in 3 patients of each group. Intestinal necrosis, progression of the lesions and extensive pelvic fibrosis were the only criteria of poor prognosis. Twenty-two operations were performed: 4 for urinary tract lesions and 18 for intestinal lesions. Five patients died during the immediate post-operative period and five died within 2 to 30 months after surgery, including 4 whose carcinoma recurred. The operative technique should be selected according to the extent and severity of radiation-induced damage, as determined by pre-operative examination and thorough exploration of the abdominal cavity once opened. Limited lesions of the small bowel can be treated by resection, but intestinal bypass with latero-lateral anastomosis seems to be preferable in cases with extensive lesions. Patients with colorectal lesions should have defunctioning colostomy prior to any other procedure dictated by the state of affairs. Multiple anastomosis, extensive resections and excessive dissections should be avoided.

Adult↗
PubMed1981

Respiratory function is impaired less by transverse than by median vertical supraumbilical incisions.

Respiratory function in the first four days after elective cholecystectomy has been compared in 15 women in whom abdominal incision was transverse and 15 in whom it was median vertical. Ventilatory function (vital capacity and forced expiratory volume in one second) and blood gas tensions (partial pressures of oxygen and of carbon dioxide in arterial blood, arterial whole-blood carbon dioxide, and alveolo-arterial oxygen tension difference) were determined on the day before operation and on the first, second and fourth postoperative days. Ventilatory function was depressed postoperatively in all the patients, but the depression was significantly less, and of significantly shorter duration, after the transverse than after the median vertical approach. Significant changes in blood gas tensions were noted postoperatively after both incisions, but without significant difference between the two groups.

Abdomen↗
PubMed1981

[Exploratory laparotomy of the acute abdomen (author's transl)].

The results of exploratory laparotomy in 48 patients with an acute abdomen are reviewed. Overall mortality was 29 p. cent (14 cases) and was influenced by three main factors: patients over 50 years of age, multiple visceral lesions, and when exploratory laparotomy was conducted for an acute painful febrile abdominal syndrome (10 deaths in 32 cases) or during the postoperative period (4 deaths in 11 cases). In contrast, exploratory laparotomy is a benign procedure in patients with abdominal contusions. It is essential, therefore, to try to establish the diagnosis before proposing laparotomy, which should only be performed when all other diagnostic investigations have proved negative.

Abdomen, Acute↗
PubMed1980

[Gastrocolic excision for ulcers and cancer. Discussion on ideal surgical procedures (author's transl)].

Seven patients were treated by gastrocolectomy for either ulcers or cancers. Two patients had ulcerating gastrojejunocolic fistulae, four had cancers of the stomach, and one had cancer fistulae, four had cancers of the stomach, and one had cancer of the transverse colon. Two patients treated by immediate colon anastomosis for cancer, died after the anastomosis broke down, while the three other cases, treated by delayed colon anastomosis, survived. Both patients with ulcerating lesions survived, one after immediate and the other after delayed colon anastomosis. This latter procedure appears, therefore, to be imperative in cancer cases and of value, when used prudently, in ulcer cases.

Adult↗
PubMed1979

Selectivity of the distal splenorenal shunt.

The distal splenorenal shunt is less likely to provoke encephalopathy than conventional shunting procedures, and it may offer a survival advantage for certain cirrhotic individuals, presumably because of its selective nature. This study suggests that the distal splenorenal shunt, even with exceptional efforts to achieve portomesenteric-gastrosplenic (PM-GS) disconnection, is not nearly as selective as it originally was assumed to be. In 11 patients intraoperative pressure determinations showed a significant decrease in portal pressure after end-to-side distal splenorenal anastomosis and no restoration of portal pressure after PM-GS disconnection. Measurements of flow through the shunt were comparable to those reported for portacaval shunts, and shunt flow was not decreased significantly by PM-GS disconnection. Postoperative angiography showed some PM-GS collateral in 17 of 18 patients, and later angiographic studies showed a tendency for progressive collateral development and consequent loss of hepatopetal portal perfusion. The advantages of the distal splenorenal shunt must accrue from gradual, as opposed to abrupt, portal deprivation, rather than from lasting selectivity.

Blood Pressure Determination↗