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Biomedical subjects

J M Friedrich

Publications and source records attributed to J M Friedrich.

At least 109 records · Page 6Linked to original sources
PubMed1988

[Biliary and arterial obstructive processes in regional chemotherapy with FUDR].

By far the majority of 54 patients suffering from hepatic metastases due to colorectal primaries developed obliterations of the arterial vascular bed when being submitted to regional chemotherapy with FUDR. In addition, about 25% exhibited obstructive jaundice in the course of severe sclerosing cholangitis. Either effect, which can be detected by radiological procedures, has to be referred to irritating activities of the chemotherapeutic drug used.

Adult↗
PubMed1988

[A complex symphalangia syndrome with brachydactyly, humeroradial synostosis and other multiple joint dysplasias].

Two members of a family affected with autosomal dominant multiple synostosis syndrome and malformations of various joints are presented, the most prominent signs being humeroradial synostosis and symphalangism. Moreover, dysplastic hip joints and familial conductive deafness as well as craniofacial abnormalities are observed. The present report may serve as an introduction to the complex radiological pattern in patients with hereditary brachydactyly syndrome.

Abnormalities, Multiple↗
PubMed1987

[Determination of the degree of stenosis in carotid artery stenoses: ultrasound and i.v. DSA in comparison to surgical findings].

The specimens from 116 consecutive carotid thrombendarterectomies were taken as "gold standard" to evaluate the accuracy of ultrasound methods (duplex scanning + extra-/transcranial Doppler sonography) and intravenous digital subtraction angiography (i.v. DSA) in carotid artery stenoses. In 65 cases, in which the specimens could be gauged reliably, sonography estimated the degree of stenosis in 85% within a range of +/- 10%, in 97% within +/- 20% i.v. DSA was accurate in 52 respectively in 94%. High-grade stenoses were correctly assessed by ultrasound in 90%, by i.v. DSA in 64%. Sonography identified 4/10 kinkings and coilings of the carotid artery, i.v. DSA 9/10. Current available ultrasound methods enable estimation of the diameter reduction of carotid artery stenoses with low deviations. I.v. DSA seems to be less reliable, but can be used favourably as a complementary method to sonography.

Carotid Artery Diseases↗
PubMed1987

[Role of digitalized angiography by venous route in the study of carotid bifurcation. Value in the diagnosis of ulcerated lesions].

Intravenous DSA was performed in 149 patients with suspected arteriosclerotic disease of the carotid bifurcation. These patients were submitted to 163 endarterectomies. The radiological and surgical findings were correlated in a retrospective analysis. The sensitivity of the angiographic method in determination of the correct percentage stenosis was 79%, but only 36% for the diagnosis of ulcerated lesions. Sonography exhibited a sensitivity of 79% with respect to the degree of stenosis and 23% in the diagnosis of ulcerated plaques. The present paper demonstrates the limiting factors of DSA and sonography. Furthermore, it reveals the valuable complementary effect of both methods in detecting arteriosclerotic lesions of the carotid bifurcation.

Arteriosclerosis↗
PubMed1986

[Transvenous DSA of the extracranial cerebral arteries. Causes of reduced image quality based on a critical analysis of 1000 patients].

In this study images of 1000 patients examined via transvenous DSA were analysed and the image quality scrutinised for each vascular region while determining the causes of image quality reduction. The results show that the diagnostic image quality was 98% (excellent/good 79%, fair: 19%) for a. carotis communis, 94% (69 and 25%, respectively) for carotid bifurcation, 84% (54%, 30%) for distal int. carotid arteries, 91% (65%, 26%) for vertebral arteries and 74% (45%, 29%) for basilar artery. Reasons for image quality reduction were artifacts due to movements by the patients, and were also due to vascular superposition. Reduced left ventricular function resulting in prolonged circulation time and dilution of contrast material was frequently combined with an advanced age of the patients (greater than 75 years). Our studies suggest that transvenous DSA is not useful in patients with significantly reduced cardiac output who do not cooperate properly and are of advanced age. It may, therefore, be omitted to avoid unnecessary stress and high cost. In such cases intraarterial DSA or conventional angiography is indicated.

Aged↗
PubMed1985

[Noninvasive diagnosis of patellar chondromalacia].

The present paper investigates into plain film appearance of chondromalacia patellae verified with the aid of operative and arthroscopic inspection. Roentgenograms taken according to the defile-technique were obtained from 86 patients prior to the operation and at post operative intervals to give a two year follow up. It can be drawn from the results that the incidence of radiologically detectable type I lesions is in the range of about 60%, whereas the diagnostic sensitivity for type III lesions have been determined to reach 100%. While significant improvement of all clinical symptoms could be observed during the postoperative period, patellar roentgen morphology proved to be almost entirely unchanged. Therefore it may speculated that severe chondromalacia patellae is likely to represent an early sign of patellar osteoarthritis.

Cartilage Diseases↗
PubMed1984

[Venous digital subtraction angiography in the diagnosis of arteriosclerotic diseases of the supra-aortic extracranial vessels].

In addition to non-invasive sonographic examinations the slightly invasive transvenous DSA has been shown to be useful in outpatients to demonstrate acceptable images of the supraaortic extracranial vessels. In preselected patients (n = 140) different atherosclerotic lesions of the examined angiographic region could be diagnosed by DSA. Images of diagnostic quality including the carotid bifurcation could be found in 88% using three examination-sequences in different standardized projections; only 43% of cases could be diagnosed following two sequences. Compared with conventional angiography DSA showed an identical imaging of the carotid bifurcation in 22 of 25 cases. Using an additional o.m. projection of the skull base (n = 80) internal carotid arteries could be analyzed in all cases, vertebral arteries in 80% and the basilar artery in 82%.

Adult↗
PubMed1982

[Congenital angiodysplasias of types F.P. Weber, Klippel-Trénaunay and Servelle-Martorell].

Basing our observations on a study of 47 cases of angiodysplasia of types F.P. Weber, Klippel-Trénaunay and Servelle-Martorell, we attempted to demonstrate that differentiation of these 3 syndromes is possible if criteria obtained from a non-invasive investigative method are used. This involves taking standard X-rays of the extremities (both sides) which are examined under direct magnification (0.1-01 mm) thus allowing the most exact possible analysis of the skeletal changes. In this way, the Weber syndrome should be suspected if bone prolongation is seen in association with loss of substances from the skeleton. In the Klippel-Trénaunay syndrome, the bone lengthening is not accompanied by bony lesions. In the Servelle-Martorell syndrome bony lesions go hand in hand with limb hypertrophy.

Angiomatosis↗
PubMedDate not supplied

Ultrasonography of capsular morphology in normal and traumatic ankle joints.

Ultrasonography was used to inspect the ankle anatomy of 20 healthy volunteers. The images produced were correlated with anatomical structures by examining three dissected cadaver ankles. The anterolateral pouch of the articular capsule was identified by ultrasonography in 91% of the normal ankle joints as a hypoechoic area. The posterolateral pouch of the articular capsule also could be identified by ultrasonography as a hypoechoic area in 84% of the normal ankles examined. The lateral aspect of 105 traumatized ankles was examined subsequently. The ultrasound results agreed in 100% of the cases with the operative findings for the anterior talofibular ligament and in 92% for the calcaneofibular ligament.

Adult↗
PubMedDate not supplied

Radiographic aspects in transcatheter contact dissolution of calcified gallbladder concrements.

The present study on 10 patients reports upon an attempt to perform percutaneous contact dissolution of partially calcified gallbladder concrements. These gallstones, which exhibited structural calcifications on CT scans, required time-consuming complex dissolution procedures with transcatheter administration of methyl tert-butyl ether (MTBE) and ethylene diamine tetraacetic acid (EDTA). Insertion of the catheter system (5 F) was performed via a percutaneous transhepatic route. Catheter placement was maintained for a maximum of 4 days. Complete lysis was achieved in seven of the ten cases. In six patients, significant regional or disseminated chemically induced cholecystitis and pericholecystitis could be observed on CT examination. However, on follow-up CT examinations, these changes proved to be completely reversible. It has been demonstrated that tolerance of the gallbladder wall and adjacent tissue layer against the lytic media employed is rather limited and that meticulous controlling of the morphological reaction can be helpful in minimizing complications.

Adult↗
PubMedDate not supplied

Flushable stent-system for internal drainage in occlusive jaundice.

The effectiveness of biliary stents may be reduced as a result of obstruction by tumor material, bile salts or detritus. To circumvent this problem we developed a prosthesis system, which allows flushing and repetitive radiological control via a subcutaneous port. Prostheses were implanted in 26 patients presenting with inoperable occlusive lesions of the bile duct. Patency was regularly monitored by checking the bilirubin and alkaline phosphatase levels and using port-cholangiography. Catheter function was easily maintained in 92% of the patients and ended upon malignancy related death. In case of dysfunction, drainage could generally be restored with intensive flushing. This new flushable stent-system was easily implantable, could be exchanged without renewed percutaneous transhepatic puncture and allowed flushing, external drainage, bile probes for bacteriological examinations and follow up cholangiography via the subcutaneous placed port.

Cholestasis↗
PubMedDate not supplied

[Echographic diagnosis of hepatic abscess (General Referral Hospital, Gbadolite, northern Zaire)].

The two most important liquefying liver diseases are the pyogenic and the amoebic liver abscess. The clinical, pathomorphological and ultrasonographic evolution is of some regularity. So a classification in three stages is of practical usefulness. The ultrasonographic characteristics of those stages for the two forms of liver abscess are presented as well as their specific treatment.

Democratic Republic of the Congo↗