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Biomedical subjects

J M Friedrich

Publications and source records attributed to J M Friedrich.

At least 73 records · Page 4Linked to original sources

[Potentialities and limitations of MR angiography in the imaging of intracranial aneurysms].

The potential value of MR angiography in imaging of intracranial aneurysms was analyzed in seven patients. Six cases were confirmed by angiography or computed tomography. In one patient MR angiography was not useful in distinguishing bleeding from an aneurysm. Five aneurysms were imaged by 3D angiography, one was diagnosed by 2D angiography. The extent of thrombosis was evaluated by selective presaturation. MR angiography was a useful non-invasive method in imaging of intracranial aneurysms. However, for complete work-up angiography is mandatory.

Humans↗

[Computed tomographic aspects of intestinal intussusception].

This article describes typical CT findings of intestinal intussusception of different genesis and localisation. It is shown that a characteristic image resembling a target is obtained both in case of an invaginated Meckel's diverticulum, an idiopathic ileocolic intussusception in an infant, and in colorectal invagination in condition after resection of a polyp of the sigmoid. Compared with the conventional imaging methods such as sonography, colon contrast enema or contrast imaging of the small intestine, CT enables not only unequivocal diagnosis of intestinal invagination but frequently also the identification or exclusion of underlying causes that trigger the phenomenon.

Colonic Diseases↗

[Sonographic detection of splenic injuries after blunt abdominal trauma].

During one year 150 patients with blunt abdominal trauma were scanned by ultrasound on the day of admittance. In 18 patients a splenic lesion was diagnosed by ultrasound. These lesions consisted of 12 splenic ruptures and of 6 splenic haematomas. The diagnosis was confirmed in 9 cases by laparotomy, in 7 cases by computed tomography and in 2 cases by sonographic follow-up. In all patients ultrasound was used in the follow-up assessment. Emergency sonography was not only a reliable diagnostic tool, but was also appropriate as an easy follow-up imaging.

Abdominal Injuries↗

[Arterial lesions following radiotherapy].

From 1980 to 1990 twelve patients with vascular lesions attributable to irradiation were treated. The time interval between radiotherapy because of malignancy and onset of symptoms due to radiation-induced atherosclerosis was on an average 7 years (1 month-29 years). A typical morphological finding at angiography was the well-localised vascular lesion in the previous radiation area, its localisation clearly distinguishable from typical atherosclerotic lesions. 10 patients had other radiation damage with involvement of the skin and perivascular tissue frequently necessitating an extra-anatomic reconstruction (n = 6). 4 patients had an anatomical reconstruction, one had a PTA, one was treated conservatively. Due to absence of multifocal arteriosclerotic lesions, long-term results of vascular reconstruction are good and will certainly contribute to further improvement of life quality after curative therapy for malignant disease.

Adult↗

[Malignant obstructive jaundice: decompression via an external bilio-gastric fistula].

In cases of malignant bile duct obstruction in which internal biliary drainage cannot be established by surgical intervention or by implantation of a stent, the externally drained bile can be recycled by connecting the transhepatic catheter to a percutaneous gastrostomy. Experiences on three patients treated by the above method are reported.

Adult↗

[Congenital and acquired anomalies of the inferior vena cava. Differential diagnosis using digital subtraction angiography and computed tomography].

Segmental aplasias of the inferior vena cava, thrombosis of the vena cava, tumour infiltration (e.g. renal neoplasms via the renal vein) and external compression (e.g. large hepatic metastases) may produce similar radiomorphologic changes in chest x-ray DSA and CT. These radiomorphological changes are described by case reports. DSA clearly demonstrates the course of the vessels and the collaterals involved. CT may elucidate the paracaval vascular changes. It is only a synopsis of cavography (DSA) and CT with reference to embryogenesis that will lead to a reliable diagnosis and enable a definite decision on therapy and prognosis.

Adolescent↗

[Cervical spinal injuries in craniocerebral trauma: their x-ray diagnosis on the day of the accident].

To investigate cervical spine injuries and to evaluate cervical radiography 100 patients were reviewed who were referred to computed tomography of the head because of blunt head trauma. 15 sustained cervical injury, 11 were located at the lower level of the cervical spine. Six fractures of the lower cervical spine were detected by additional radiographs. The diagnosis was established by computed tomography in three cases. To rule out cervical injuries in patients with incomplete visualisation of the lower cervical spine, cervical computed tomography should be performed in addition to lateral, anterioposterior, and open-mouth views.

Adult↗

[Biliary obstruction: MR-cholangiography with a rapid gradient-echo sequence (2D CE-Fast)].

Magnetic resonance (MR) was used to delineate the biliary tree in patients with obstructive jaundice originating from various types of malignant or benign processes at different locations. With the aid of a rapid sequential gradient-echo acquisition (CE-Fast) and 3D post-processing, heavily T2-weighted images could be obtained to identify the site of obstruction in ten out of eleven patients. Slices were acquired during breath-holding periods of about 12 sec with a total examination time of 10-15 min. The three-dimensional display reliably demonstrated the dilated bile ducts in pre-stenotic areas whereas in the majority of cases post-stenotic ductal segments could not be visualised.

Cholangiography↗

Dilated biliary tract: evaluation with MR cholangiography with a T2-weighted contrast-enhanced fast sequence.

A heavily T2-weighted gradient-echo sequence was used for magnetic resonance (MR) imaging of the biliary system in five healthy volunteers and 13 patients with obstructive jaundice. Images were obtained in the sagittal and coronal planes during sequential breath-hold intervals and were post-processed by using a maximum-intensity projection algorithm. The extrahepatic and intrahepatic bile ducts were well visualized in 11 patients. The level of obstruction and the grade of dilatation were depicted with MR cholangiography. However, the cause of obstruction could be determined with MR cholangiography in only eight cases. The part of the biliary system below the obstruction could not be visualized with MR cholangiography. In the volunteers, MR cholangiography could demonstrate the anatomy of the biliary tract in only two subjects. Possible causes for this phenomenon are the limited spatial resolution of MR imaging, partial volume effects, or flow within the bile ducts. MR cholangiography may be a useful adjunctive tool for noninvasive evaluation of patients with obstructive jaundice. However, further technical advances are necessary to improve image quality.

Bile Ducts↗