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Biomedical subjects

J M Favriel

Publications and source records attributed to J M Favriel.

39 records · Page 3Linked to original sources

[Rupture of an aneurysm of the splenic artery into the pancreas, a rare cause of gastrointestinal bleeding (author's transl)].

In a 73 year old man, repeated gastrointestinal haemorrhages first attributed to peptic oesophagitis, recurred despite anti-reflux surgery. Upper endoscopy being negative, arteriography was performed which revealed the presence of a fissured aneurysm of the splenic artery. This was successfully treated by left splenopancreatectomy. A communication between the aneurysm and wirsung's duct was found in the operative specimen. This a very rare cause of gastrointestinal bleeding. The diagnosis can be made only by arteriography.

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["Non-secreting" plasma cell myeloma preceded by refractory sideroblastic anemia (author's transl)].

The authors report the association of a refractory sideroblastic anemia and a "non-excreting" plasma cell myeloma. The anemia was observed 8 years before the onset of the myeloma, which had typical hematological characteristics. Both kappa and gamma light chains were found in the cytoplasm and on the surface of the plasma cells. Pathologic characteristics of this type of myeloma are briefly recalled, as well as the relationships between sideroblastic anemia and kahler's disease, an example of disorders of two lines of hematopoiesis (erythrocytes and leucocytes).

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[Angiodysplasia of the right colon: a frequent cause of lower digestive tract hemorrhage. Apropos of 13 cases].

13 observations of right hemorrhagic colic angiodysplasia were detected in less than 5 years: 9 times with proctorrhagia of varying amounts, 4 times with an endoscopic aetiological evaluation of iron deficiency anemia. Colonoscopy revealed lesions in 11 patients out of 13 in the form of erythematous spots of vascular hemorrhagic appearance in 5 cases. The arteriography was positive in 5 of the 7 cases where it was performed. Treatment was endoscopic 6 times, by follow-up electrocoagulation, 2 times, by right hemicolectomy. The latter was carried out immediately in 2 other cases. In 5 cases, iron treatment was all that was necessary. These right colic angiodysplasias are often an unknown cause of digestive hemorrhage or iron deficiency anemia. The difficult diagnosis depends on the colonoscopy performed by an operator accustomed to this type of lesion. It is carried out in emergency in cases of acute bleeding. Sometimes an arteriography is also performed. Endoscopic treatment may be an alternative to standard surgical treatment in elderly high-risk patients.

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