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Biomedical subjects

J M Cormier

Publications and source records attributed to J M Cormier.

At least 127 records · Page 7Linked to original sources

[Takayasu's disease. Diagnostic criteria (author's transl)].

Retrospective analysis of the records of 86 patients with Takayasu's disease confirmed that the condition is more common in women, that it is frequently associated with a history of tuberculosis and that angiography is of considerable help in showing vascular lesions that are characteristic by their location (common carotid artery, post-vertebral subclavian artery) and by their diffusion to various areas. Histological examination of 20 surgical specimens confirmed the diagnostic value of sclerosis of the media and adventitia (associated or not with inflammatory lesions) and therefore radically different from the lesions of the intima observed in Horton's disease. Diagnostic criteria based on clinical, radiological and histological data are proposed.

Aortic Arch Syndromes↗

[Takayasu's disease involving the vessels arising from the arch of the aorta and those of the upper limbs (author's transl)].

Lesions localized to the vessels arising from the aortic arch and those in the upper limbs were observed in 72 out of 84 patients with Takayasu's disease. In 54% of these 72 cases, other regions were affected, while only the vessels arising from the arch of the aorta were the site of lesions in the other 46% (isolated axillo-post-vertebral subclavian lesions were present in 14% of cases). Semiological features, long-term complications, and prognosis are discussed. 53 revascularizations were performed in 47 patients without mortality. Surgery is definitely indicated when severe stenosis of the brachiocephalic vessels or the main carotid arteries or their division exists. Revascularization of a subclavian artery stenosis should be limited to cases with ischemia of the upper limb on effort or when a histological diagnosis is required. Controversy exists as to the need for this operation in ectatic forms.

Aortic Arch Syndromes↗

[Intraluminal angioplasty in the treatment of femoro-popliteal atheromatous lesions. Apropos of 57 cases].

Close cooperation between radiologist and surgeon is essential to prevent major complications of intra-luminal angioplasty, an only mildly aggressive revascularization procedure. Though evolution of an arteritis of the lower limbs can be halted by relief of the stenosis in some cases, the problem remains as to whether this technique is justified at the stage of claudication, even severe. The wider indications for dilatation at the iliac in relation to the femoropopliteal levels in this most recent series reported, testify this tendency.

Aged↗

[Venous graft versus carotid thromboendarterectomy (T.E.) (author's transl)].

497 cases of carotid stenosis were operated upon with 2 operative series: one with a venous graft technique and the other by thromboendarterectomy (T.E.). 228 grafts were thus compared with 192 T.E. during the initial postoperative period and 2 and a 1/2 years follow up. The prevalence of immediate postoperative complications was lower in the venous graft group than in the T.E. group but the distribution of patients in terms of neurological symptomatology was not strictly identical. By contrast, comparison of the asymptomatic patients in the two groups showed no morbidity nor mortality. It is thus not possible to state that vein graft is superior to T.E. in the prevention in particular of early embolic complications with the thromboendarterectomized zone as the point of departure and the follow up period is too short to assess the superiority of one or other method in the long term. During the 2 and a 1/2 year follow up period of the present study no pathology related to the vein graft has been seen, confirming the trial already reported.

Adult↗

[Associated lesions of the aorta and visceral arteries. A special anatomo-clinical form of atheromatous disease].

The data of 124 observations of atheroma associated lesions of the aorta and its visceral branches, renal and mesenteric was collated. This retrospective study makes it clear that cases of atheromatous lesions involving the renal and mesenteric arteries can be considered as a special group. Aortic lesions above the level of the renal arteries have a variable outcome--the most commonly seen pattern is that of a thick circumferential plaque which encroaches on the openings of the visceral arteries. These lesions are either ulcerated or smooth and sometimes overlain by voluminous mural thrombus above the renal arteries. This group is associated with widespread atheromatous disease in the coronary and cerebral circulations. The prognosis is poor. A special approach to management is thus required since many arteries are affected and since usually, associated revascularization of the aorta and these four visceral branches is not present. This form of treatment is justified by a post-operative mortality of nil. There is a 50% mortality at three years, almost completely due to coronary disease.

Aorta, Abdominal↗

[Clinical presentations of Cockett's syndrome. 16 cases].

Cockett's syndrome (iliac compression syndrome) results from compression of the common iliac vein by the aortic bifurcation. The anatomical abnormality is frequent (15-20% of the population), but symptoms only appear when compression is pronounced. In a study of 16 patients, predominantly female, the following clinical presentations were observed: venous oedema of the left lower limb in 4 cases; symptoms suggesting iliac phlebitis in 3 cases; pulmonary embolism as first sign of peripheral venous thrombosis in 6 cases; and deterioration of angiodyplasia in 3 cases. In all patients, the diagnosis of Cockett's syndrome was confirmed by cavography. Surgical treatment, successfully performed in 13 patients, consists of uncrossing the artery and vein and placing a clip on the vena cava in case of pulmonary embolism

Adolescent↗

[Deformities of the feet after Volkmann's ischemia in the lower limb (author's transl)].

The authors have observed 11 cases of Volkmann's ischemia in the lower limb. The main deformity was of equinus. 10 patients were operated on. In 8 cases, arthrolysis was performed with good results in 7 cases. In 2 cases an ankle arthrodesis was done with one good result and one secondary amputation. The surgical technique of the arthrolysis is described. In most of the cases, tendon lengthenings, capsulotomy and fixation with an external fixator was required. This device was tolerated and it is concluded that it is worthwhile in severe ischaemic syndrome and that arthrolysis is preferred to arthrodesis.

Adolescent↗

[Contralateral shunt of a restored aorto-iliac axis for atheromatous aorto-iliac lesions (author's transl)].

Reparative surgery of an iliac axis was conducted on 35 patients with atheromatous aorto-iliac lesions, and was completed by a contralateral shunt as an "alternative" between a prosthesis and a bifemoro-aortic thromboendarteriectomy. Reconstructive surgery on the donor axis included a thromboendarteriectomy alone or combined with a venous graft in 31 cases, an aorto-femoral vein graft in 3 cases, and an external iliac angioplasty in 1 case. The contralateral shunt was by a vein graft in 29 patients, and a prosthesis in the other 6 cases. Two complications occurred, one due to progression of the atheromatous lesions on the unobstructed aorto-iliac axis, the other being related to fibrous stenosis of a crossed vein graft. Post-operative follow-up over periods ranging from 6 months to 6 years confirmed the good vascular prognosis.

Aorta↗

[Diffusion of atherosclerosis in patients with arterial disease of the lower limbs (author's transl)].

In patients with arteriosclerosis obliterans of the lower limbs immediate (operative risk) and long term prognosis depend on the diffusion of the atheroma to other arterial beds (coronary and carotid). Basic investigations were completed by doppler ultrasonography of the cervical arteries, exercise electrocardiogram and lateral aortogram. Doppler ultrasonography revealed significant degrees of stenosis of the cervical arteries in 67 out of 402 patients (16.6 p. 100). The stenosis were totally latent clinically in 13 patients. Valid results were obtained in 72 p. 100 of 140 after an exercise electrocardiogram. It was positive in 19 p. 100 of patients without clinical or electric sign of coronary heart disease. Lateral aortogram in 125 patients showed atheromatous lesions in 39 cases (31 p.cent). These were often multiple and involved the coeliac and superior mesenteric arteries in 13 cases. These investigations are of great importance in making the therapeutic decision, indications related with risk and resulting priorities. Alarming coronary or carotid lesions may indeed require treatment before arterial disease of the lower limbs.

Aortography↗

[Partial occlusion of the inferior vena cava by clips. Indications and results about 95 cases (author's transl)].

Vena cava clips were applied in 95 patients between October 1975 and October 1979, without mortality directly related to the surgical intervention. One patients died early after operation due to an associated thoracic aorta aneurysm. The 10 deaths occurring at a later stage were not related to the insertion of the clips or its consequences. One patient developed a pulmonary embolism during operation, as a result of a concomitant juxtarenal thrombectomy. Postoperative extension of a femoropopliteal thrombosis or bilateralization of an iliac phlebitis was observed in 31 p.cent (30 out of 95) of cases. Permeability of the inferior vena cava was confirmed in 32 patients, 65 p. cent of the clips remained patent. Lower limb venous sequelae, related to the insertion of the clip or its consequences, were noted in 34 p.cent (24 of 69) but caused little inconvenience. Severe venous disorders, due to the thrombo-embolic disease, were always present before the insertion of the clips. Postoperative morbidity was low, the clip causing extension of previously existing venous thrombosis, without significant distal sequelae. The absence of recurrence of pulmonary embolism demonstrates the efficacy of this method. The employ of a caval filter to preserve improved permeability of the inferior vena cava (IVC) is discussed.

Adolescent↗

[Transposition of the common iliac artery onto the contralateral hypogastric artery (author's transl)].

On fourteen occasions the authors have used an original technique of anastomosis between the common iliac artery and the contralateral hypogastric artery. This technique can be applied to the surgical treatment of Cockett's syndrome. But it is also useful in some emergency situations, such as traumatisms or surgery in septic environment, as it restores the arterial blood flow without prosthetic bypass when the common iliac artery is sacrificed.

Aneurysm↗

Local urokinase in arterial thromboembolism.

Selective intra-arterial urokinase (UK) is effective in treating recent arterial thromboembolism. However, usually only partials lysis is achieved and this treatment seems less effective than intravenous streptokinase. At a dose of 37,500 UCTA/hour it does not produce systemic fibrinolysis. This protocol substantially reduces the risk of systemic bleeding and embolism and extends its applicability to operative patients. The combination of surgery and UK seems particularly promising in patients with atherosclerotic arterial thrombosis.

Adult↗

[Extrinsic compression of the popliteal artery (author's transl)].

Popliteal artery compression may be due to trapping of the artery, a tumor, or a subadventricial cyst. Diagnosis is suggested by the discovery of ischemia in a subject who is often young, this being an unusual finding. It is confirmed by dynamic doppler tests, ultrasonography, and vascular opacification. Eight cases of trapped popliteal, three of osteochondroma, and seven cases due to cysts were observed. Surgical treatment is regularly effective and can prevent complications of embolism and acute thrombosis.

Connective Tissue Diseases↗

[Vascular complications after the treatment of carcinoma of the cervix (author's transl)].

Vascular complications after this treatment are rare. Artery stenosis or occlusions, more often iliac, are well recognized complications of postoperative radiotherapy. These segmental lesions, sometimes, are pathological lesions similar to arteriosclerotic changes. These lesions may be corrected later on after the treatment of carcinoma of the cervix. The venous complications often present later and tall within the context of post thrombotic syndrome. Conservative treatment is indicated alone. A well recognized complication, lymphedema is usually mild; a superimposed iliofemoral thrombophlebitis often may be suspected.

Adult↗