Conversion of sorbitol to mannitol was shown by the unexpected discovery of the urinary excretion of mannitol when urinary levels were being measured in connection with the surveillance of patients suffering from malnutrition or head injury and receiving total parenteral nutrition: glucose, sorbitol, amino acids and soya oil. The presence of mannitol in thr urine would appear to result from a secondary catabolism through a physiological pathway for the fructose produced by the metabolism of sorbitol not broken down during glycolysis.

Chromatography, Gas↗

PubMed1975

[The utilization of EB 51 in parenteral feeding. Clinical, biological and anatomopathological control. Statistical study on 30 patients].

Two groups of patients (comas of central origin and serious digestive undernourished) were submitted to an exclusive or a supplementary parenteral feeding for a short or a long period of time totaling over 500 days. The catheter was placed (in 80 p. cent of the cases) in a deep vein and was tunnellized. EB 51 (Trivemil) used in those 30 patients gives amino-acids, lipids and glucides. The caloric intake was completed by 30 p. cent glucose solutes. If the average caloric intake was 3.000 calories per day, it was often above that figure since the feeding was combined with a nutri-pump enteral feeding for 60 p. cent of the days. The clinical tolerance was quite good. On a biological level, in addition to classic investigations, 40 analytic graphic records of lipid levels were made, as well as a quantitative analysis of serous triglycerides and lipurias, a study of sorbitol and 500 nitrogen balances combined with 150 chromatographies on the acidaminuria column. An hepatic biological control was also made (amnoniemia, transaminases) as well as a quantitative analysis of lactates, pyruvates and minerals: iron-phosphorus-magnesium. Some of the results were checked by statistical studies. No serious anomaly was detected. Lung and hepatic biopsies carried out upon 9 patients did not apparently reveal any lipidic overloading. The clinical and the biological investigation show that this complete nutriment is perfectly tolerated and assimilated.

Amino Acids↗

PubMedDate not supplied

[Transformation of sorbitol to mannitol when used in parenteral administration].

This was shown by the unexpected discovery of the urinary excretion of mannitol when urinary sorbitol levels were being measured in connection with the surveillance of patients suffering from malnutrition and head injury and receiving total parenteral nutrition: glucose, sorbitol, amino-acids, soya oil. The presence of mannitol in the urine would appear to result from a secondary catabolic through physiological pathway for the fructose produced by the metabolism of sortibol not metabolised during glycolysis.

Adolescent↗

PubMedDate not supplied

[Diffusion of gentamicin and tobramycin in the plasma and ascitic fluid of cirrhotic patients. Influence of the route of administration].

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Aged↗

PubMedDate not supplied

[Severe pneumopathy due to Legionella pneumophila: report on two cases].

Two patients with severe forms of legionnaires' disease presented similar manifestations of a confusional syndrome, a major infectious syndrome resistant to cyclines, beta-lactams, and aminoglycosides, altered hepatic and renal functions, and a fulminating course with the need for assisted ventilation in one case. Indirect immunofluorescence serology gave very positive results in both patients and changes in serum levels were reported 6 and 8 months after the onset of the disease. A serotype I strain of Legionella pneumophila was isolated by direct immunofluorescence from bronchial aspiration products in the second case. These cases are discussed in relation to reports in the published literature.

Humans↗