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Biomedical subjects

J M ASKEY

Publications and source records attributed to J M ASKEY.

15 recordsLinked to original sources

Anticoagulant drug treatment of coronary artery disease.

Anticoagulant therapy of arteriosclerotic heart disease may prove to be most valuable when applied on a long-term basis for prevention of recurrent myocardial infarction. While its prophylactic value in impending infarction has not been established, at least the accepted treatment for the acute stage is already begun if an anticoagulant has been administered before an inevitable infarction occurs. The chief value of the anticoagulant, though, seems to lie in preventing cardiac mural thrombosis and extracardiac thromboembolism. It is by this effect, apparently, that mortality has been reduced by 50 per cent among survivors of myocardial infarction who receive continuous dicoumarin therapy. While the danger of hemorrhage is still present, it is being steadily reduced by increasing skill in the management of anticoagulant therapy, and for a long time the risk has been far outweighed by the reduction in coronary occlusion. Physicians have a duty to learn the use of anticoagulant therapy, obtain the facilities necessary for it, and apply it to patients who are able and willing to cooperate in prolonging their useful lives.

Anticoagulants↗

Dental extraction during dicumarol therapy.

Extraction of 14 teeth in six patients taking dicumarol caused no unusual bleeding. Discontinuance of dicumarol prior to dental extraction should not necessarily be a routine procedure; in certain persons with a demonstrated strong tendency to recurrent thrombosis, dicumarol should be continued, based on the decision that the danger of clotting without the drug is greater than the danger of bleeding with the drug.

Coumarins↗

Alcoholism.

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Alcoholism↗