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Biomedical subjects

J Luna

Publications and source records attributed to J Luna.

48 records · Page 3Linked to original sources
PubMed1984

Role of pineal gland in kidney-adrenal homeostasis.

The effects of pineal gland on kidney-adrenal axis have been studied in male rats. Rats were pinealectomized and exposed to a photoperiod of 12 h light: 12 h dark. Plasma renin activity (PRA), corticosterone and corticotropin (ACTH) levels were measured at 10, 20 and 35 days postpinealectomy. Pinealectomy increased corticosterone and ACTH levels and decreased PRA in all age groups. A significant negative correlation was found between corticosterone and PRA, which suggest that changes in PRA were due to changes in circulating corticosterone, via feedback mechanism on renin secretion. On the other hand, melatonin administration prevents these effects of pinealectomy. It is suggested that the lack of this pineal indol is responsible for the pinealectomy-induced alterations in male rats.

Adrenal Glands↗
PubMed1979

[Liver disease associated with hypernephroma. A case report (author's transl)].

The observation of a non-metastatic reactive hepatopathy associated with a hypernephroma in a 39-year-old man who had had fever for 4 months led to a review of the literature and an analysis of basically three aspects of the disorder: a) The various manifestations of carcinoma of the kidney, which include a large number of paraneoplastic clinical symptoms (polycythemia, anemia, prolonged fever, hypercalcemia, hypertension, nefropathy, loss of salt, peripheral neuropathy, and amyloidosis); b) an alteracion of hepatic function known since 1961 which is characterized by an abnormal retention of sulfobromophthalein, increase of alkaline phosphatase, prothrombin decrease, dysproteinemia with hypoalbuminemia, and alpha2-globulin increase. It may or may not be accompanied by enlargement of the liver. c) Criteria of operability of the primary tumor.

Adenocarcinoma↗
PubMed1978

[Hypophyso-gonadal function in infancy. From newborn to puberty (author's transl)].

Serum levels of testosterone, follicle stimulating hormone and luteinizing hormone have been measured in 216 healthy children (104 boys and 102 girls) divided in 9 groups from newborn to puberty. Testosterone serum concentrations were significantly higher in boys than in girls during the first 4 months after birth. Testosterone values were highest in 1 to 2 month old boys. Serum concentrations of both FSH and LH changed in different patterns in both sexes. During the first 4 years FSH concentrations were significantly higher in girls than in boys. During the first 4 months, however, LH concentrations were higher in boys than in girls.

Adolescent↗
PubMedDate not supplied

Percutaneous mitral commissurotomy.

Rheumatic fever is the most common cause of acquired heart disease in children and young adults worldwide, mainly in developing countries, and is the reason that a large number of patients with mitral stenosis will require some modality of treatment during their life span. The early therapeutic approach for this condition was solely surgical, but since the early 1960s, several balloon catheter interventional techniques have emerged as alternatives to surgical treatment. In 1976 Inoue described a novel single-balloon device designed specifically for percutaneous transvenous mitral commissurotomy (PMC), and in 1982 the first clinical application of Inoue's technique was successfully accomplished. Ever since several clinical trials established PMC as an effective and safe procedure for severe mitral stenosis in more than 30,000 patients worldwide, percutaneous balloon techniques have been considered the method of choice in selected patients (functional class >II, mitral valve area <1.5 cm2, and Wilkins' score <8) for several reasons. PMC is a nonsurgical method with results similar to those of surgical intervention, but without the unnecessary risks and complications of general anesthesia and extracorporeal circulation pump. Both PMC and surgical commissurotomy yield comparable acute and long-term results and similar restenosis rates. Moreover, PMC is the strategy of choice in symptomatic pregnant women with mitral stenosis, as well as in some cases with restenosis after a previous PMC. Patient selection and procedural technique are reviewed in detail.

Adolescent↗
PubMedDate not supplied

[Comparative analysis of reperfusion time in primary angioplasty vs thrombolysis. Success vs time].

UNLABELLED: We studied 398 patients with diagnosis of acute myocardial infarction who arrived within the first six hours of symptom onset that were treated with thrombolysis or primary angioplasty, they were divided in two groups: Group 1 (n = 198), those treated with 1.5 million U of streptokinase over 60 min and Group 2 (n = 200), those treated with primary angioplasty. In Group 1 the "pain-door" time was 3.7 +/- 1.7 hs vs 3.8 +/- 2.4 hs in group 2 (p = NS). The "door-needle" time was 48 +/- 12 min. compared with the "door-balloon" time of 84 +/- 30 min (p < 0.001). In Group 1, 154 (77.6%) of the patients had clinical of reperfusion after thrombolysis, 58 of them underwent coronary angiography and had an infarct related artery (IRA) patency rate of 45.3%. In Group 2 the IRA patency rate was 85.5% (p < 0.005). CONCLUSION: Thrombolysis was achieved in a lesser period of time but our findings showed that primary angioplasty was more effective obtaining a TIMI 3 flow.

Acute Disease↗