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Biomedical subjects

J Linares Solano

Publications and source records attributed to J Linares Solano.

13 recordsLinked to original sources

Phakomatosis pigmentovascularis and Lisch nodules. Relationship between Von Recklinghausen and phakomatosis pigmentovascularis?

In 1947, Ota described a malformative syndrome associating a vascular component (nevus flammeus) with melanocytic or epidermic nevi, which he named phakomatosis pigmentovascularis (PPV). We will discuss the case of a 10-year-old boy presenting giant nevus flammeus, nevus spillus, asymmetry in the development of both lower limbs, characteristic of PPV, together with interventricular communication and Lisch nodules, representative of Von Recklinghausen's disease. We believe that this case can be classified as PPV type IIb, associated with Lisch nodules and rarely described in Caucasian individuals.

Child↗

Cutaneous extranasal NK/T-cell lymphoma.

Malignant neoplasm from natural killer (NK) cells are characterized by their positivity for CD56 and absence of monoclonal TCR gene rearrangement. We present the case of a 54-year-old man with a fungous mass in his left flank whose histological examination was consistent with cutaneous extranasal T/NK cell lymphoma. We review the literature and also discuss the prognosis and treatment of this variety of lymphoma.

Antineoplastic Combined Chemotherapy Protocols↗

Cutaneous melanoma extirpated with insufficient surgical margins.

A major controversy in the treatment of melanoma is the width of the surgical margin necessary for complete excision. We have reviewed the case histories of 1125 patients at the Melanoma Unit of the Dermatology Department of the San Cecilio Clinical Hospital in Granada from 1988 to 2000. The first aim was to verify whether there is a statistically significant correlation between occupied margins and other prognosis factors. We also analyse the situation after re-excising the scar from the previous extirpation with a minimum margin of 1 cm.

Humans↗

[Angiokeratoma. Apropos of 93 cases].

A description of 93 cases of angiokeratoma [Mibelli (3 cases), Fordyce (13 cases), circumscriptum naeviformis (12 cases) and solitary (65 cases)], confirmed histologically and observed during the last 30 years (1955-1985) in the Department of Medicine and Surgery of the School of Medicine of the University of Granada is presented. We carry out a detailed histological and ultrastructural study.

Angiokeratoma↗