Biomedical subjects

J Lilja

Publications and source records attributed to J Lilja.

At least 19 recordsLinked to original sources

PubMed1995

A longitudinal study of speech in 15 children with cleft lip and palate treated by late repair of the hard palate.

Since 1975, children with cleft lip and palate living in the western part of Sweden have been treated according to a regimen of early repair of the soft palate (at the age of 6-8 months) and late hard palate closure (at about 8-9 years of age). The present paper is a longitudinal study of 15 consecutive patients whose speech development was analysed at the mean ages (years:months) of 5:3, 7:0, 8:5, and 9:7 years. Hypernasality gradually decreased over the years whereas nasal escape almost completely ceased after closure of the residual cleft. There was no glottal articulation at any age. Despite the fact that retraction of apicodental consonants decreased in frequency with age and presumably with speech therapy, it was the main problem throughout the observation period. It was presumably caused by the residual cleft in the hard palate compensating for subnormal pressure in front of the opening to the nasal cavity.

Age Factors↗

PubMed1991

Craniofacial and occlusal characteristics in unilateral cleft lip and palate patients from four Scandinavian centres.

Craniofacial morphology and dental occlusion were studied at early school age in 15 consecutive patients with unilateral cleft lip and palate from each of four Scandinavian cleft centres. Treatment differed mainly in the techniques of palatal repair. Push-back closure of the palate particularly impaired maxillary development, which resulted in an increased incidence of crossbite and reduced intercanine distance when compared with patients who had been operated on by the von Langenbeck method or in whom the anterior palate had not yet been closed.

Cephalometry↗

PubMed1991

Repositioning of craniofacial tumorous bone after autoclaving.

Thirteen bone tumours that were invading the craniofacial skeleton were operated on by intracranial procedures. The resected tumorous bone was autoclaved and put back. Follow up of no less than one year included 122mTc scanning, computed tomography, radiography, bone biopsy and clinical examination. In every case, when rigidly fixed, most of the autoclaved bone was gradually revitalised by invading new and normal bone. We conclude that autoclaved bone will be replaced by normal bone, and that the present technique is justified for reconstruction of complicated structures or large areas of bone after operations for tumours invading the craniofacial skeleton.

Adolescent↗

PubMed1990

Trigonocephaly: clinical and cephalometric assessment of craniofacial morphology in operated and nontreated patients.

Craniofacial parameters were studied clinically and by cephalometry in 11 trigonocephalic patients from infancy to 4 years of age. Six of the most severe patients had surgery between 6 and 18 months of age. Analysis of morphology indicated that bony interorbital distance was reduced in patients selected for surgery and hypotelorism persisted at final examination. All patients demonstrated orbital width measurements above the mean for the norm, while orbital height was essentially normal. All but one of the patients had a variably prominent forehead bony ridge that was eliminated or reduced as a result of surgery and/or growth. However, the forehead of most patients, whether operated or not, was too narrow when compared to normal skulls. Thus, although some of the striking features of trigonocephaly are eliminated, minor characteristics of the anomaly still persevere at 4 years of age.

Cephalometry↗

PubMed1990

Posterior repositioning of the entire maxilla without postoperative intermaxillary fixation. A clinical and cephalometric study.

In 30 patients posterior repositioning of the entire maxilla has been performed. No postoperative intermaxillary fixation (IMF) has been applied. The surgical procedure is described and data given on the distance of repositioning. Results of cephalometric analysis indicate good long-term stability after surgery. We concluded that omitting IMF not only enhances patient comfort, but has no deleterious effect on postoperative stability of the maxilla.

Adolescent↗

PubMed1990

Cleft lip and palate patients prior to delayed closure of the hard palate: evaluation of maxillary morphology and the effect of early stimulation on pre-school speech.

Speech and maxillary development were analysed in two groups of patients with unilateral cleft lip and palate; both groups had early jaw orthopaedic treatment and a surgical regimen that included two-stage lip surgery (mean ages of 2 and 19 months) and soft palate repair (8 months). Closure of the hard palate was postponed until the children were 8 to 10 years of age. The first group comprised 10 consecutive patients who were analysed at 5 and 7 years of age, and the second group seven patients who were studied at the age of 5. Both groups were thus investigated before the repair of the cleft in the hard palate. In addition to surgical and jaw orthopaedic treatment, the second group of patients received early stimulation of lip and tongue tip movements. Our results indicated that hypernasality was less a problem than was retracted palatal or velar articulation of dental consonants. These deviations tended to be reduced, however, after early stimulation. There seemed to be no clear association between the size of the residual cleft in the hard palate and the extent of speech development. The average size of the residual cleft in our patients was comparatively small, and decreased further during follow up. We conclude that preschool children with unilateral cleft lip and palate may develop good speech, in spite of the residual cleft, if they use an intraoral plate and are given extra lip and tongue tip stimulation, together with early speech therapy if necessary.

Child↗

PubMed1989

Sagittal split osteotomy of the mandible without postoperative intermaxillary fixation. A clinical and cephalometric study.

A modified sagittal split technique has been evaluated in 42 dentate patients, in whom no postoperative intermaxillary fixation was used. Twenty-three patients had mandible set-back performed and 19 patients mandibular advancement. The method makes possible a safe split osteotomy under controlled conditions. The design of the osteotomy and screw osteosynthesis counteracts relapse. Omitting intermaxillary fixation facilitates postoperative handling of the patient and promotes rehabilitation.

Adolescent↗

PubMed1989

Maxillary osteotomies without postoperative intermaxillary fixation (anterior, superior and inferior repositioning of entire maxilla). A clinical and cephalometric study.

Surgical correction of maxillary anomalies with anterior-superior or anterior-inferior repositioning of the segment was performed in 50 patients. The maxillary segment was stabilized by means of steel wires as horizontal mattress sutures, which, in all cases, gave very good primary stability. In case of insufficient bone contact miniplates were used. Postoperatively no rigid intermaxillary fixation (IMF) was applied. There are several advantages to not using intermaxillary fixation: 1) It is possible to carry out immediate postoperative inspection of the location of the condyles and thereby confirm that the segments are in the expected position. 2) Segment fixation is not disturbed by mandibular movements during recovery from general anaesthesia. 3) Manipulations by the anaesthesiologist immediately after surgery are not interfered with. 4) For the patient there is better postoperative comfort with no breathing, talking or feeding problems. 5) Minor corrections of intercuspation by means of orthodontic elastics are possible. These can act in the required direction and will not disturb the masticatory function. Masticatory function was resumed immediately after surgery and was usually normalized within 2-3 weeks. Cephalometric analysis revealed no significant relapse subsequent to surgery. Thus we conclude that omitting IMF, among other advantages, enhances patient comfort and has no negative effect on the postoperative stability of the maxilla.

Adolescent↗

PubMed1988

Simultaneous correction of maxillary and mandibular dentofacial deformities without the use of postoperative intermaxillary fixation. A clinical and cephalometric study.

Simultaneous correction of maxillary and mandibular anomalies was performed in 23 patients. The maxillary segment was stabilized by means of steel wires as horizontal mattress sutures, which, in all cases, gave good stability. A modified sagittal split has been applied in all cases. The method makes a safe split osteotomy possible under controlled conditions. The design of the osteotomy and the screw osteosynthesis counteract relapse. Postoperatively, no rigid intermaxillary fixation (IMF) was used. Masticatory function was started from the 1st postoperative day and in most cases was normalized 2-3 weeks after surgery according to the patients own judgement. Cephalometric analysis was performed on 15 patients by a superimposition technique. There was an overall good postoperative stability of the maxilla and mandible in the horizontal and vertical planes. We conclude that omitting IMF has no negative effect on the postoperative stability of the fragments.

Adolescent↗

PubMed1988

Features of maxillary arch and nasal cavity in infancy and their influence on deciduous occlusion in unilateral cleft lip and palate.

The purpose of this study was to test the statistical relationship between certain preoperative characteristics of the maxilla and nasal cavity and later occlusal development in patients born with complete unilateral cleft lip and palate. The sample consisted of 51 patients and 22 of them had undergone surgical treatment which included vomer flap and pushback palatal repair, while the remaining 29 patients were treated with a routine characterized by delayed closure of the hard palate. Twelve variables related to 4 different maxillary and nasal areas were recorded from maxillary casts and frontal cephalograms obtained in infancy. Crossbite scores and maxillary intercanine width were determined from dental casts taken at 3 years of age. Multiple linear regression analysis showed that the preoperative variables selected as predictors of maxillary development at the age of 3 did not explain more than half of the variation found in our subjects. Also, the predictors were not the same in the two surgical subgroups. To improve our ability to predict, further variables should be tested and, if possible, added to the regression formulae.

Child, Preschool↗

PubMed1988

The step technique for the reconstruction of lower lip defects after cancer resection. A follow-up study of 165 cases.

One hundred and sixty-five patients with localized cancer of the lower lip were excised and reconstructed over a 25-year period using Bengt Johanson's step technique. Eight-eight percent of the tumors were less than 2 cm in size and 65% were of high histopathological differentiation. Fifty-six percent were reconstructed with bilateral step flaps. Nine local recurrences appeared in 5 patients, none of whom died of lip cancer. Eight patients later developed regional metastases and 3 of these patients died of lip cancer. The 5-year survival rate was 98%. The step technique is recommended for reconstruction of lip defects of up to 2/3 of the lower lip and may, in larger resections, be combined with either a fan flap or an Estlander flap. The outstanding functional results are due to the use of adjacent tissue for the reconstruction which preserves the normal arrangement of muscles, vessels and nerves.

Adult↗

PubMed1987

The nationalization of the Swedish pharmacies.

The first Swedish parliamentary bill suggesting government-owned pharmacies was introduced in 1907 and was rejected. A number of official proposals were put forward until 1970 when the government decided to nationalize the Swedish pharmacies. The process leading to nationalization was influenced by background and by more specific 'release' factors operating in the 1960s. The opposition in parliament to nationalization was only minor. The new organization formed, Apoteksbolaget AB, was given a drug selling monopoly and was organized as a limited company regulated by an agreement between the government and Apoteksbolaget.

History, 19th Century↗

PubMed1987

Orthognathic surgery with no postoperative intermaxillary fixation.

In 113 patients orthognathic surgery was performed. Both maxillary, mandibular and combined procedures were used. Intermaxillary fixation was avoided in all cases. It was found that the procedures presented offer a safe correction of the jaw with minimal complications during surgery and in the postoperative period. Preliminary data suggest that the stability of the segment is in good accordance with procedures with intermaxillar fixation.

Adolescent↗

PubMed1987

Facial morphology and occlusion at the stage of early mixed dentition in cleft lip and palate patients treated with delayed closure of the hard palate.

Cephalometric radiographs and dental study casts were analyzed in a group of 23 seven-year-old cleft lip and palate patients, 16 with unilateral and 7 with bilateral cleft. The patients' primary surgical procedures had been completed except for closure of the cleft in the hard palate. For comparison, similar records from another group of patients, 18 with unilateral and 8 with bilateral cleft lip and palate, were studied. In these cases the cleft of the hard palate had been repaired in infancy, using a vomer flap procedure. The results indicated that midfacial growth and dental occlusion of the unilateral cleft sample was significantly better in patients whose closure of the hard palatal cleft had been delayed to the stage of mixed dentition than where repair had been performed with a vomer flap in infancy. No differences were found, however, between similar subgroups with bilateral cleft lip and palate.

Cephalometry↗

PubMed1987

Bone grafting at the stage of mixed dentition in cleft lip and palate patients.

Our results of bone grafting to the alveolar process during the mixed dentition were investigated in 55 consecutively treated patients (66 clefts). The amount of remaining bone and gingival retraction at the tooth mesial to the cleft after 3 and 12 months was measured and correlated with the following anatomical conditions present during surgery: width of the cleft, rotation of the adjacent incisor, stage of eruption of the tooth distal to the cleft. It was also considered if any deciduous lateral incisor or canine was extracted during surgery and if any flap dehiscence took place postoperatively. It was found that flap dehiscence resulted in significantly less bone at 3 months and at 1 year after surgery. Furthermore, extraction of a deciduous tooth was found to be significantly correlated to less bone 1 year after surgery, in which cases there were also persisting gingival retractions. The other factors had no significant influence on the outcome of surgery.

Alveolar Process↗

PubMed1986

Craniofacial surgery for trauma.

Craniofacial surgical techniques have yielded as an important spin-off better methods of treating severe craniofacial trauma. In this paper surgical techniques are discussed. It was concluded that the most important factors for successful reconstruction after craniofacial trauma is to do as much as possible the first time, to obtain wide exposure, ensure rigid fixation of bone pieces and grafts and to make use of a work bench procedure where bone fragments are assembled on a side table for subsequent reattachment to the head.

Adult↗

PubMed1986

The craniofacial approach to trauma.

Craniofacial surgical techniques have yielded better methods of treating severe craniofacial trauma. In this paper surgical techniques are discussed in principle and specifically presented through case reports. We conclude that the most important factors for successful reconstruction after craniofacial trauma are to do as much as possible the first time, to obtain wide exposure, to ensure rigid fixation of bone pieces and grafts, and to make use of a workbench procedure where bone fragments are assembled on a side table for subsequent reattachment to the head.

Adult↗

PubMed1986

Airway obstruction and sleep apnea in children with craniofacial anomalies.

Children with severe craniofacial anomalies and breathing problems are rare, and the accumulated experience of their treatment is limited. LeFort III midface advancements have been tried by many craniofacial teams, but no consensus has yet been reached as to the effectiveness of this procedure. In this report of seven patients with craniofacial malformations and severe breathing problems, three had a LeFort II midface advancement, one had release of bilateral temporomandibular joint ankylosis, and two had tonsillectomies. Two patients without a tracheostomy suffocated, four had a long-term tracheostomy, and one was cured by a unilateral tonsillectomy. It was concluded that LeFort III midface advancement is ineffective in these types of cases without a very stable postoperative retention, and it was suggested that all patients with severe craniofacial anomalies and breathing problems, regardless of their planned subsequent treatment, should have a tracheostomy as an initial measure.

Acrocephalosyndactylia↗