[Articular manifestations in primary hemochromatosis: their diagnostic significance at the previsceral stage of the disease].
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Biomedical subjects
Publications and source records attributed to J Lefebvre.
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Total body water (T.B.W), extra-cellular fluid volume (E.C.F.), exchangeable sodium (NaE) and potassium (KE) were measured in one typical case of Bartter's syndrome with growth retardation. Intracellular potassium depletion was associated with a slight impaired carbohydrate tolerance and with decreased growth hormone response to arginine infusion and insulin-induced hypoglycemia. These observations demonstrate that impairement of growth hormone responses to stimulation occur in Bartter's syndrome with potassium depletion.
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The exceptional nature of compact, extensive calcifications in a giant pituitary adenoma points to the possibility of immunological, histological and chemical mechanisms in the calcification process.
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In a sibship, 4 out of 5 children featured pseudo-hypoparathyroidism. The following points were verified: hypocalcaemia; increase of the serum level of PTH; normal response of bone and gut effectors to endegenous PTH; contrast between normal bone X-rays and lesions detected by histological studies.
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