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Biomedical subjects

J Leborgne

Publications and source records attributed to J Leborgne.

At least 109 records · Page 6Linked to original sources

[Cecum perforation, complication of an acute idiopathic dilatation of the colon, or Ogilvie's syndrome. Practical interest of various pathogenic data. Apropos of one case].

The authors report a new case of caecal perforation complicating acute dilatation of the colon without organic obstruction (Ogilvie's syndrome). They recall the two characteristics of this syndrome : abdominal distension due to colonic ileus, without any organic cause, and the constant coexistence of an associated pathological condition (traumatic, post-operative, infective, cardio-vascular, respiratory or neurological). The major complication is caecal perforation, announced by a clinical and radiological preperforative syndrome. The pathogenesis of Ogilvie's syndrome remains mysterious. Two facts are worth attention : the role of the sympathetic nerve in intestinal paralysis and the direct intervention of an extra-intestinal pathological factor in the onset of this syndrome. Hence two therapeutic consequences : the favourable effect of splanchnic infiltrations on intestinal motility, and the parallel course of acute colonic dilatation and the extra-intestinal disease.

Cecal Diseases↗

[Endométriosis of the small intestine. Report of 4 new cases of stenosis of the small intestine (author's transl)].

The authors report 4 new cases of stenosis of the small intestine of endometrial origin. They emphasize the rareness of these stenosing forms which in most recent series intervened in 1 case of endometriosis out of 1,000 (Martinbeau). They consider the various clinical presentations encountered, asymptomatic forms discovered by chance, forms associated with suggestive gynecological disorders, chronic stenosis of the small intestine or presentation with intestinal obstruction. They consider the diagnostic difficulty in the isolated forms (2 cases) in the absence of pelvi-genital lesions. Among the positive factors, they consider the recrudescence during theperiods of the digestive signs, the macroscopic appearance of the lesions and, above all, the mucosal integrity noted on opening the specimen after intestinal resection. Finally, they consider certain special problems, that of bi-polar intestinal involvement with double localisation, involving the ileum and the recto-sigmoid areas.

Adult↗

[Multinodular hepatic angioma: a rare cause of neonatal asystole. A case and review of the literature].

The clinical findings in a case with a diffuse multinodular type of angioma of the liver are reported. The clinical picture was typical: the appearance after the first week of a severe congestive failure mimicking a congenital heart disorder, of the left to right shunt type, with gross hepatomegaly of the "vascular" type with a systolo-diastolic murmur, but with no cutaneous evidence of angioma. The very severe prognosis during the first months of life of patients with this malformation, as illustrated by the 58 deaths out of the 78 cases reported in the literature, indicated ligature of the hepatic artery before the age of one month. The satisfactory outcome (with a nine months follow-up) for this case, as for the three other operated cases in the literature, leads us to conclude that this operation is indicated after a detailed arteriographic examination has been made, and provided that the other anatomical conditions are favourable.

Arrhythmias, Cardiac↗

[Post-traumatic sequestra of the liver].

The authors report 92 cases of trauma of the liver which survived initial operation and study the special problems linked to hepatic sequestration. They analyse the factors which favour the appearance of these sequestra and the methods of diagnosis using clinical, laboratory, arteriographic and scintigraphic data. Relatively frequent (8,4 p. 100), these complications require fairly early surgical treatment. They are commonly localised to the dome of the liver and this renders their approach difficult. A low postero-lateral thoracotomy with resection of the 10 th or 11 th rib, followed by sequestrectomy and drainage, seems to them ideal approach. The pleuropulmonary sequelae are minimal.

Adolescent↗

[The azygos system].

The great variety of anatomical dispositions of the azygos system explains its facility of adaptation. The second lumbar vein is able to play a buffer role between the caval systems or, conversely, is able to direct venous flow to a preferential system. In case of portal hypertension, an inferior omphalo-azygos flow by the right ascending lumbar vein was noticed. Finally, the left venous system may either be the major element of the azygos system (mainly by a big ascending lumbar vein) or be divided in 2 distinct streams to the azygos venous trunc. The final disposition of the azygos system seems to correlate well with a progressive evolution towards an unique trunc, linking directly the two caval systems (this being confirmed by foetal data). Practically, the study of the arterial and venous relations of the azygos crossing have interesting applications in surgery.

Azygos Vein↗

Solid tumors of the liver. Diagnostic and therapeutic problems.

The diagnostic and therapeutic problems involved in 29 cases of isolated hepatic tumors have been presented. In nine cases the hepatoma was discovered during emergency treatment for complications. Selective arteriography was the most accurate method of establishing the etiologic diagnosis. Suprahepatic phlebography indicated the possibilities for surgical treatment. These possibilities are not influenced by the volume of the tumor, but are closely dependent on damage to the suprahepatic vascular system. Effective surgery was performed in 22 cases, of which 14 were excisions.

Adolescent↗

[Familial cancer of the parathyroid glands. Importance of angiography in the diagnosis of regional recurrences. Considerations on 2 cases].

The authors report two new cases of functional parathyroid carcinoma, the course of which varied between 5 and 7 years. The main fact was their familial character, as the disease affected two siblings. No similar case was found in the world literature. These two cases were characterised by symptoms in the bones or pancreatic symptoms which dominated the whole clinical course. Finally, the second case was studied by angiography which permitted the authors to localise a lymphnode metastasis on the opposite side. As far as treatment was concerned, the frequency and severity of local and regional spread justifies wide removal at an early stage. This attitude is necessary in any case of parathyroid tumor with an infiltrating character.

Adult↗