Search PubMed⌕ Search

Biomedical subjects

J Lapierre

Publications and source records attributed to J Lapierre.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[Changes in fluorescent antibodies in experimental bilharziasis with S. mansoni and S. haematobium in mice. Comparison of the results obtained using homologous and heterologous antigens].

Fluorescent antischistosomiasis antibodies appear earlier in mice infected by 150/200 cercariae than in those who only received 20. The use of a homologous antigen in mice infected by S. mansoni or S. haematobium allows earlier and more important responses. The infections by S. haematobium seem to determinate in mice a more important immune responsiveness. Is it a specific parasitic manifestation (S. mansoni being better adapted to rodents?).

Animals↗
PubMedDate not supplied

[Schistosoma mansoni and haematobium antisera tested by homologous and heterologous antigens. Comparison of the results obtained by indirect immunofluorescence technic].

The study of anti Schistosoma mansoni and anti Schistosoma haematobium sera by homologous and heterologous antigen shows that Schistosoma haematobium has an immunogenic strength as good as that of Schistosoma mansoni. The joint use of the two antigens can be useful in epidemiologic investigations in Africa so as to track down seats of Schistosoma mansoni and Schistosoma haematobium and the prevalence of the infection.

Animals↗
PubMedDate not supplied

[Comparative study of the value of Schistosoma mansoni and Schistosoma haematobium antigens in the indirect immunofluorescent reaction applied to the diagnosis of rectal S. intercalatum bilharziasis].

A comparative study of the value of antigenic sections of S. mansoni and S. haematobium in indirect immunofluorescence applied to the diagnosis of S. intercalatum rectal bilharziosis (in 66 cases) shows that far better results are obtained with S. haematobium antigen (83,3 0/0 positive reactions with higher titers dilution) than with S. mansoni (33,3 0/0 positive reactions).

Adolescent↗
PubMedDate not supplied

[Malaria].

Explore the source record for details and available documents.

Antimalarials↗
PubMedDate not supplied

[Often unrecognized cutaneous manifestations of strongyloidosis: linear dermatitis or larva currens (author's transl)].

The linear dermatitis of "larva currens" is a typical manifestation of strongyliasis, however is generally too unrecognized. It is observed in about 7% of cases, more frequent in white race. Due to the migration of Strongyloides larvae in epidermis of sensitized person, it appears in form of rectilinear urticaria from 10--30 cm, developed from 12--48 hours and disappeared without leaving any trace. It can appear at any place of the body, sometimes in many places simultaneously. The total duration of the evolution similiar to that of strongyliasis can be developed during a many tenth of years. In reality the differential diagnosis is easy with filariasis (loa-loa) and specially with cutaneous larva migrans (ankylostomiasis, creeping eruption, larbish). The thiabendazole cures the strongyliasis nad its cutaneous manifestations in 85% of cases with a single oral dose of 6 tablets 6 x 250 mg).

Adolescent↗
PubMedDate not supplied

[Wuchereria bancrofti and asthmatic pulmonary signs in Upper Egypt].

A biological and clinical survey was conducted in 25 patients with bancroftian filariasis, consulting the El Nikhela Health Centre, Assiout Governorate, Upper Egypt. Eleven patients showed asthmatic bronchitis. According to parasitological and serological data (specific antibodies level, total IgE), those clinical manifestations cannot be considered as a part of the "eosinophilic lung" syndrome. In this area, where Wuchereria bancrofti has been recently introduced and where there is an increasing degree of infection, bancroftian filariasis seems to predispose to allergic manifestations.

Adolescent↗
PubMedDate not supplied

[Drug resistance of Plasmodium falciparum and Plasmodium vivax strains in Cambodia (Cardamone Massif). Morphological characteristics of Plasmodium vivax].

The authors report some failures of chemoprophylaxis and curative treatment of Plasmodium falciparum and Plasmodium vivax malaria. These infections were contracted in the area of the cambodian-thaï border by 8 Europeans treated by various regimens and 34 Cambodians treated by quinine. In the latter group, the quinine failure rate in Plasmodium falciparum infections was about 47% (RII or RIII?) and 17,5% in Plasmodium vivax. Total cure of vivax malaria with usual doses of Primaquine among the Europeans, failed in 3 out of the 6 treated patients. Morphological particularities (abnormal pigment, lack of Schüffner dots) were noticed in these Primaquine resistant vivax strains. A possible relation is considered between Primaquine resistance and these morphological particularities.

Antimalarials↗
PubMedDate not supplied

[Epidemiologic study of 2 foci of Schistosoma mansoni bilharziasis in Togo (Lama Kara and Kpalimé). Comparative efficacy of oltipraz (RP 35972)].

The authors note a very high prevalence of schistosomiasis mansoni in the two foci studied in Togo (Lama Kara in the North and Kpalimé in the South-West); however, the prevalence is significantly higher in Lama Kara (79.5%) than in Klonou (54.7%); this was calculated on both coprological and serological basis. The parasite burden is identical in the two foci; but, the GMRT is higher in Lama Kara than in Klonou (31.7 and 8) which might be explained by a different immunogenicity of the two strains. It is noticed schistosomiasis mansoni might be responsible for hepatosplenomegaly found in the two foci, especially in Lama Kara, which might be explained by a higher virulence in this location. The treatment by oltipraz (RP 35972) had a 91.9% success rate in Klonou (similar to our results in Paris). However, in Lama Kara, even though the drug was taken with some food--increasing its biodisponibility--, the treatment was less effective at day 180 (76.5%). The authors wonder whether the difference of oltipraz efficiency between the two foci is based on a difference of biology between the two strains of Schistosoma mansoni in Lama Kara and in Klonou.

Adolescent↗