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Biomedical subjects

J Lapides

Publications and source records attributed to J Lapides.

At least 37 records · Page 2Linked to original sources

New approach to myelodysplasia.

Data from 60 patients with myelodysplasia are presented. Electromyography of the periurethral striated muscle in conjunction with simultaneous cystometry allows prediction of those patients at risk from urinary tract infection in 100 per cent of the cases. Intermittent self-catheterization is an effective form of therapy for bladder dysfunction in patients with myelodysplasia. An orderly approach to the evaluation and management of bladder dysfunction is outlined.

Adolescent↗

Prostatitis.

Explore the source record for details and available documents.

Adult↗

Comparison of rapid versus slow decompression of the distended urinary bladder.

Experiments are described showing that urinary retention with its associated increased intravesical pressure and overstretching of the bladder wall can lead to loss of capillary and tissue integrity. Our findings indicate that the severity of damage to the bladder wall prior to catheterization determines the degree of hemorrhage after bladder decompression and not the rate of emptying.

Animals↗

Observations on interstitial cystitis.

Interstitial cystitis is more common in young women than previously believed. Findings typical of the disease are a history of diurnal and nocturnal pollakiuria, pelvic discomfort increases with bladder distention, marked bladder tenderness on gentle palpation of the anterior later vaginal fornices, less than normal bladder capacity, and a negative urinalysis except for many epithelial cells.

Cystitis↗

Cutaneous everted nipple ureterostomy.

Normal dog ureter transplanted to the skin by the everted nipple ureterostomy technique was found to be far superior to the skin flap ureterostomy in nevovascularization and healing of the stoma. The results suggest a possibility of successful application in the human; recent clinical experience supports animal data.

Abscess↗

Therapy questionably infarcted testis.

Observations made upon dogs and humans with apparent infarction of the testis secondary to torsion of the spermatic cord suggest that the treatment of choice for questionably viable testis is detorsion of the cord, replacement of the testis in its hemiscrotum, and fixation of the opposite testis. This form of therapy may be applicable to all "torsed testes" regardless of viability.

Animals↗

Urecholine test for denervated bladder-.

In the dog the denervation supersensitivity response of the detrusor appears within 7 to 21 days after bilateral pelvic nerve transection. Unilateral denervation cannot be detected by the standard Urecholine test.

Animals↗

Further observations on self-catheterization.

A non-sterile technique of intermittent self-catheterization was used for 218 patients with an inability to void in a normal fashion because of obstructive uropathy, decompensated detrusor or neurogenic bladder. Marked improvement was not in urinary continence, urinary infection, renal function, bladder emptying and, perhaps most important, the mental and emotional status of the patient and/or parents. The extremely low incidence of complications and its therapeutic efficacy clearly make clean, intermittent self-catheterization an outstanding weapon in the urological armamentarium and a most persuasive reminder that host resistance is still the primary factor in the occurrence of infection.

Adolescent↗