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Biomedical subjects

J Lang

Publications and source records attributed to J Lang.

At least 523 records · Page 29Linked to original sources
PubMed1976

[Peculiar capillary convolution of the parietal pleura. III. Electron microscopy studies].

By means of electron microscopy and ultrahistochemical research it has been attempted to detail the structure and explain the function of the pleural tufts of the parietal pleura present in the ventral mediastinum of dogs. This led to the discovery that the varions forms present for the surface-enlarging pleura protusions in actuality exhibit corresponding morphological characteristics. As a special formation of the serous lamina of parietal pleura, they are covered by an occasionally incomplete mesothel unit. The parenchyma of these organs is compinsed of a macrophage-rich outer border zone and of a vessel-canying central zone. The experimental in vivo application of cationized ferritin in the pleura-space clearly indicated a high resorptive metabolism of the mesothel and of the pluripotential mesenchym cells. The higher incidence of lymphoplasmatic cell-forms in the proximity of the central vessels along with leucocytic cell infiltrations fulfill an immunocellular and phagocytic function. The structure of the cell population of the pleural tufts partaking on the resorption of matter out of the pleural space has been discussed in detail. The in vivo application of a cationized ferritin solution for the purpose of studying these resorptive processes has been critically judged.

Animals↗
PubMed1976

[The origin and ramifications of the intracavernous section of the internal carotid artery].

The fine ramifications of the internal carotid artery arising in the cavernous sinus were minutely prepared and investigated on 23 heads: 1) Origins, branchings and their variations have been systematically traced. 2) The areas supplied by the carotico-cavernous ramifications of the internal carotid artery their anastomoses and positioning to one another have been analysed and classified. 3) Three schematic illustrations prepared from the specimens dissected summarize and annotate the findings. 4) The diagrams have also been included which summa iza and compare the results of earlier investigators. The newly discovered and heretofore unpublished variations have been included along with a comparison to these of the already varying terminology extant for the origins, branchings, final destinations and relationships.

Aged↗
PubMed1975

Isolation and characterization of three phospholipases A from the crotoxin complex.

1. Three phospholipases A (phosphatide acyl-hydrolase, EC 3.1.1.4) have been isolated from the crotoxin complex, the main toxic compound of the Crotalus durissus terrificus venom. 2. Two basic phospholipases A were highly purified from the crotoxin complex by single chromatography on carboxymethyl cellulose. The yields were 10% and 38% (w/w), respectively. They showed no differences with regard to isoelectric point, enzymatic activity, immunological properties, and toxicity. One acidic phospholipase A, purified to a final yield of 1-3% by chromatography on carboxymethyl cellulose, gel filtration on Sephadex G-50, and chromatography on DEAE-cellulose, was found to have one third of the specific enzymatic activity of the basic enzymes. The acidic phospholipase A was nontoxic and antigenically different from the basic enzymes. 3. Crotapotin, an acidic peptide of the crotoxin complex (31% yield, w/w), potentiated the toxicity and inhibited the enzymatic activity of the basic phospholipase A isoenzymes, but did not interact with the acidic phospholipase A. 4. The purified enzymes were homogeneous with respect to cellogel electrophoresis, polyacrylamide gel electrophoresis, dodecyl sulfate-gel electrophoresis, immunoelectrophoresis, and isoelectric focusing. 5. The molecular weights of the three phospholipases were found to be in the same range as determined by gel filtration in 6 M guanidine - HCl (14 500) and dodecyl sulfate-gel electrophoresis (15 800). The isoelectric points of these enzymes were at 9.7 and 4.8 for the first two and the third, respectivlar. The acidic enzyme contained more acidic instead of basic amino acid residues. The two methionine residues of each phospholipase were found to be positioned nearby the NH2 - and the C-terminal of the protein chains. A third methionine residue was demonstrated in the acidic phospholipase A. Fingerprint maps of the basic enzymes showed only slight differences. 7. NH2 - and C-terminal sequence analyses indicated a striking homology between the three Crotalus phospholipase A isoenzymes and several phospholipases from other sources.

Amino Acid Sequence↗
PubMed1975

Preliminary evaluation of di-iodo-triglucosyl benzene. An approach to the design of nonionic water-soluble radiographic contrast media.

A new compound, di-iodo-triglucosyl benzene (DTB), was synthesized and tested for contrast medium potential. It is stable and soluble in water, with a molecular weight of 864 and a viscosity of 33.3 cps at 40degrees C for a 66.6% w/v solution. It is rapidly excreted unchanged by the kidneys. Its estimated LD50 in mice at an intravenous injection rate of 330 mg l/min is 34.0 g/kg. It is highly hydrophilic and not epileptogenic, but its low iodine content (29.4%) makes it unfavorable for clinical use.

Animals↗
PubMed1975

[Fixation devices for the cover-test (author's transl)].

A special fixation device for distance consisting of a music box and a fixation light with changing colour is described. For near examination a fixation bar with a vertical row of pictures and numbers, and a fixation cube with pictures are recommanded.

Child↗
PubMed1975

[The vascularisation of the periorbita].

1. The periorbita is extensively vascularised from the side of the bone and the orbita. The vessels are interconnected so that the periost is not vascular boder area. 2. In the periorbita of the adult there is a dense capillary plexus which is less close-meshed on the inside. 3. Meandrian arteries and vascular loops exceptionally as long as 6 mm were found in the inner layers of the periorbita and in the adjacent layers of the fat connective tissue. 4. Flat membranes of fat connective tissue which are connected with the inner layer of the periorbita by long vascular streaks about on the inner surfaces of the periorbita. 5. On the outer surface of the periorbita venules 40 to 60 mum wide were found entering the periorbital bone. In the fissures area further meandering venules and venes were found which open in the cavernous sinus (in addition to the Vv. ophthalmicae) or enter the bordering bone. 6. N. and A. infraorbitalis run outside of the periorbita. 7. The nerves leave the periorbita by special channels and run through near and husk-like processes of the periorbita which accompany them up to the outer periost. In the bone they five off bone vessels.

Adipose Tissue↗