Biomedical subjects
J Lang
Publications and source records attributed to J Lang.
Variations in herpes simplex virus isolated from human ganglia and a study of clonal variation in HSV-1.
Growth of human sensory ganglia in culture has led to the reactivation of herpes simplex virus from over 50% of cases studied. Infected cell polypeptide and restriction enzyme analysis has led to the conclusion that each individual has one unique latent strain of HSV-1 that can be present in more than one ganglion in the body. Analysis of 91 isolates has shown that the long region of the genome is variable in terms of DNA restriction sites, DNA sequences, and in coding for the majority of variable polypeptides. The short region is stable with only polypeptides Vmw 21 and 22, restriction sites HindIII-(M-N) and BglII-(G-H) and the DNA sequence BamHI-1' having been found to vary. The insertion and deletion of small DNA sequences at specific locations allows individual reactivation events to be distinguished. Detection of information able to complement and produce ts+ virus on superinfection of otherwise negative ganglia with ts mutants, has led to the conclusion that ganglion cells may harbor herpes virus-related information that is only detectable by use of such genetic probes.
Reading capacity in cases of 'cured' strabismic amblyopia.
Fifty cases of cured amblyopia were examined in relation to distance vision, near vision, and reading capacity. Occlusion had been abandoned at age 8; the examination was made at age 12. Although linear vision for distance and near was full, reading capacity was markedly impaired. In order to prevent this 'reading amblyopia', sneaking-out or tapering-off occlusion with alternating calibrated filters is continued until the child can read fluently with each eye.
[External eye muscles and their attachment zones].
There were examined in situ the length, the diameter and the insertions of the 4 recti and the levator on 59 orbits, furthermore the mm. obliqui in the same way. The M. levator palpebrae superioris has an average length of 42.13 mm on the right (r) and 40,24 mm on the left (l). It is at the origin 3,93/3,54 (r/l)1 mm wide and 15.23/4.89 mm on the transitional area to its aponeurosis. The M. rectus superior is (mean) 37.31/37.02 mm long, in the middle area 8.59/7.83 mm wide and 2.32/2.20 mm thick. Its tendon in 4.29/4.26 mm long and 10.43/9.84 mm wide. The M. rectus medialis has an averaged length of 37.68/37.33 mm, a width of 9.41/9.73 mm and a thickness of 3.80/3.70 mm. Its tendon is 3.04/3.90 mm long and 10.39/9.92 mm wide. The M. rectus inferior is (mean) 36.95/37.70 mm long, 4.73/4.50 mm wide and 3.87/3.92 mm thick. Its tendon is 4.70/4.66 mm long and 8.50/8.68 mm wide. The M. lateralis has an average length of 36.36/35.94 mm, a width of 10.87/10.32 mm and a thickness of 2.87/2.54 mm. Its tendon is 7.19/7.82 mm long and 9.57/9.22 mm wide. Its longitudinal part is (mean) 37.59 mm (right) and 38.54 mm (left) long and 5.74/5.63 mm wide and 2.30/1.94 mm thick. Its oblique tendinous part has an average length of 22.12/22.93 mm, a width of 9.85/9.55 mm and a thickness of 1.50 mm (r/l). The M. obliques inferior is 31.46/30.92 mm long, 7.56/7.13 mm wide and 2.54/2.50 mm thick. The bulbus oculi has a longitudinal outer diameter of 24.57/24.8 mm and transversal diameter of 23.63/23.56 mm (mean). Its vertical diameter is 23.29/23.18 mm. The transversal diameter of the cornea is 11.70/12.08 mm, the vertical diameter 10.80/11,06 mm. Besides of these measurements the distances were estimated between the muscle-tendons and the cornea as well as the optic nerve.
[Shape and size of the corpus callosum and the septum pellucidum].
The mean are of the Corpus callosum at median sagittal sections of 100 brains of adults comes to 622 (330 to 900) mm2. The Corpus callosum has a mean length of 73.7 (62 to 86) mm and a mean height of 23.06 (16 to 31) mm. The Genu corporis callosi has a mean thickness of 11.68 mm and the Splenium of 11.98 mm. The Truncus has a greatest thickness of 6.68 and a smallest thickness of 4.49 mm on an average. In the rostral third the Truncus has a mean thickness of 6.11 mm, the middle of the Corpus callosum of 5.66 mm and the support of the Fornix 5.75 mm. The Corpus fornicis supports in the mean of 48.45 mm behind the rostal end of the Genu corporis of the underneath area of the Corpus callosum. This is observed in 77% in the third, in 19% in the fourth and in 4% in the second quarter of the Corpus callosum. The Septum pellucidum has a mean surface area of 292 (100 to 700) mm2 at median sagittal sections.
[Vessel architecture of cortical arteries of the human cerebrum].
The typical vascular patterns of cortical and medullar arterial vessels of the human brain in the subarachnoidal space are described. In compact arrangements and by bundles they penetrate the cortex, always in vertical direction to the cortex surface. From the top of gyri the medullar arteries run rectilinear through the cortical and medullar tissue. Medullar arteries which entrance the slope of the gyri turn in the direction of the medullar fibres after penetration the grey matter. Often glomerular-loop formations of medullar arteries are found in senile brain in the zone of fibrae arcuatae longae et breves.
[Arteriae cerebri media, region of origin and width of their cortical branches].
Origin, diameter and right-left differences of the cortical rami of the middle cerebral artery were examined in 101 hemispheres. Included are also the length, diameter and the types of furcation (bifurcatio, trifurcatio, quadrofurcatio).
[New findings on the course of the anterior cerebral artery, (pars post-communicalis), on their regions of origin and the width of their cortical branches].
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[A. laminae tecti (quadrigemina) and rami thalamogeniculati (author's transl)].
Origin, course and ramification of the "A. laminae tecti" (quadrigeminal artery) and the Rr. thalamogeniculati were examined on 115 Hemispheres by microdissections. The A. lamina tecti arises from the posterior cerebral artery in the area between 12 mm proximal and 10 mm distal of the junction with the posterior communicating artery. This vessel is doubled in 18% and has an outer diameter from 0.37 mm (Mean). It leaves Rr. interpedunculares, pedunculares and R. colliculi craniales which origins, number, courses and anastomoses were determined. The R. thalamogeniculati were estimated in similar manner.
Excretion of carbimazole and propylthiouracil in breast milk.
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The maximum activities of enzymes that are involved in substrate cycles in liver and muscle of obese mice.
The maximum activities of some dehydrogenases and enzymes involved in substrate cycles are increased in both liver and muscle of obese mice. This suggests that endocrine control rather than maximum capacity of the activities of enzymes constituting such cycles is impaired in obese mice.
Linen conservation.
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[Ethmoidal arteries: origin, course, regions supplied and anastomoses].
The origin, course and regions supplied by the ethmoidal arteries were studied on 30 injected adult heads. After branching off, the anterior ethmoidal artery normally makes a single smooth loop by first coursing forwards and then, reversing itself towards the anterior ethmoidal foramen, it goes into the canal portion, likewise without bend or angularity. Occasionally, a common ethmoidal artery or a common source for the ethmoidal arteries is present. Very rarely does the artery fail entirely. As a rule, the posterior ethmoidal artery arises from the ophthalmic artery. Occasionally, however, it is missing or can even very rarely arise from the A. meningea media. The artery usually crosses over the superior oblique muscle while the anterior ethmoidal artery usually goes under the same muscle. In the fossa olfactoria, the ethmoidal arteries give off their most important dura and bone branches in the anterior cranial fossa and then continue into the walls of the cavum nasi. The courses and variations along with ipsi- and contralateral anastomoses are likewise demonstrated.
[Strabismological terminology (author's transl)].
Differences and confusion in strabismological terminology are pointed out, i.e. in fixation behaviour, in classification of strabismuc angle, in naming of scotomas. On the whole about 20 differences in different languages are discussed.
[Round table discussion on early childhood convergent squint].
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Ultrasonic absorption in the human breast cyst liquids.
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[The incorporation of the trigeminal ganglion].
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[Nystagmus (author's transl)].
In 37,500 patients 291 cases of nystagmus were found. Jerky nystagmus of latent typ was the most frequent form, pendular nystagmus the next. Jerky nystagmus of gaze paretic type, micronystagmus, nystagmus amblyopicus and endpoint nystagmus are compared and contrasted.