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Biomedical subjects

J Landmann

Publications and source records attributed to J Landmann.

87 records · Page 5Linked to original sources
PubMed1981

The anatomic evolution of coronary artery disease demonstrated by coronary arteriography in 256 nonoperated patients.

Coronary arteriography was performed twice in 256 nonoperated patients, including 92 surgical candidates who were recatheterized because of the long wait for surgery. Criteria to define progression and regression were established in advance. Analysis of separate segments, reflecting separate lesions, revealed that progression percentages increased proportionally with the degree of initial narrowing and the interval between catherizations, ranging from 1.2% to more than 20%. The highest progression percentages were shown by the proximal right coronary artery, the left anterior descending artery distal to the first septal and first diagonal branches, and the obtuse marginal branch of the circumflex artery. In 56.3% of the patients, progression was found in at least one segment, ranging from 40% in patients who were recatheterized within 1 year to 92% in patients who were recatheterized after 5 years or longer (p less than 0.025). In 12 patients (4.7%), regression had occurred; in two cases obstructions had reverted to less than 50% narrowing. Regression was associated with progression in other branches in three cases. Indications for recatheterization did not correlate significantly with progression, but a higher progression percentage was found in patients who had sustained a myocardial infarction during follow-up than in those who had not (p less than 0.05). Comparison of potential surgical procedures based on the first and second angiogram revealed that at the second catheterization more distal anastomoses were required to achieve complete revascularization in 29.3% of the patients and that left ventricular contractions had deteriorated markedly in 15.6%. These fractions correlated with the duration of the interval between catheterizations.

Acute Disease↗
PubMed1980

[Results following Trillat's surgery in habitual shoulder dislocation].

Following a review of the surgical methods to correct habitual dislocation of the shoulder we report on the method and the results of the Trillat procedure. The first 13 patients operated upon have been investigated 1 1/2 to 3 1/2 years postoperatively. All remained free of recurrence; the mean loss of external rotation was 13 degrees. Subjective results showed that 11 out of 13 patients were satisfied or highly satisfied.

Bone Screws↗
PubMed1976

Regression of coronary artery obstructions demonstrated by coronary arteriography.

To determine the incidence and clinical features of regression of coronary artery obstructions we reviewed the angiograms of 93 nonoperated and 201 operated patients who had repeated coronary arteriographic studies. Regression of obstructions was found in 4 nonoperated cases (4.3%), all involving the left anterior descending artery. This was associated with improvement of the patient's clinical condition in only 1 case. No regressions were found in the surgical cases. Our data demonstrate that regression of coronary artery obstructions is rare and unrelated to clinical parameters.

Adult↗
PubMedDate not supplied

Demonstration of albumin receptors on isolated human hepatocytes by light and scanning electron microscopy.

The presence of albumin receptors on the plasma membrane of isolated human hepatocytes was investigated employing albumin-coupled latex minibeads. Hepatocyte-latex reaction was visualized by phase contrast and scanning electron microscopy. The experiments demonstrate that hepatocytes exhibit binding activity for polymeric and monomeric forms of glutaraldehyde-treated albumin. Additionally, the reaction was shown to be species-nonspecific. These findings support the hypothesis that polymerized albumin may act as a bridge between receptors on hepatitis B virus and human hepatocytes.

Cell Membrane↗
PubMedDate not supplied

Giant mitochondria in "zero-hour" transplant biopsies.

Giant mitochondria in kidneys have increasingly been observed since the introduction of Cyclosporin A (CSA) as immunosuppressant in kidney transplants and in patients with autoimmune disorders. In animals treated with CSA, giant mitochondria were also described. In a study of "zero-hour" biopsies taken immediately before or after reperfusion of the renal transplant, giant mitochondria were often unexpectedly found. Retrospective analysis revealed that a significant increase in the number of giant mitochondria is more often associated with CSA therapy than ischemia. Giant mitochondria with sparse cristae seem to prevail in ischemia, whereas those with dense matrix and crystalloid structures predominate in CSA therapy.

Adolescent↗
PubMedDate not supplied

[The course of varicose disease. Parallel retrospective study of 2 ethnic groups (Catania-Basel)].

Authors presents a retrospective study with two different ethnic groups, one of them from Catania and the other from Basilea, with varicose veins and subjected to a saphenectomy. They studies the following parameters: age at the entrance, and when varicose veins appeared; correlation between varix appearance date and subjective symptomatology; and rapport between varix complications and its duration. The possible incidence of "ambiental factor" and contrasts between the two groups are considered.

Adult↗