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Biomedical subjects

J Lammer

Publications and source records attributed to J Lammer.

At least 145 records · Page 8Linked to original sources

Congenital bile duct dilatation (Caroli's disease--Grumbach's disease).

Congenital bile duct dilatation is an autosomal recessive inherited disease. Pathologically tortuous dilated, dysplastic intrahepatic bile ducts were found. It may be associated with hepatic fibrosis (Grumbach's disease), or without (Caroli's disease). A common additional finding is an infantile polycystic kidney. Three cases are reported and the radiological and sonographic findings are discussed.

Adult↗

[Pancreas cancer: staging with dynamic computerized tomography].

Carcinoma of the pancreas continues to present a most unfavorable prognosis. 90% of the tumours cannot be operated on and the survival time of these patients is 2-6 months. In a prospective study based on 23 patients it was investigated whether comprehensive staging of the carcinoma of the pancreas can be performed via computed tomography so that operable carcinomas alone must be presented for laparotomy. Results of CT were compared with those of angiography and laparotomy. Differentiation between stage 1 (tumour restricted to organ) and stage 2 (limited lymph node metastasising) is limited if effected via CT. However, it was possible to differentiate between the non-operable stages 3 and 4 with a sensitivity of 88% and a specificity of 78%. CT showed particularly high sensitivity in patients with vascular involvement.

Adult↗

[Radiation-induced vasculopathy of the carotid artery and vertebral artery].

The article reports on a case of radiation-induced vasculopathy of the vessels of the head and neck causing a transitory ischaemic attack 14 years after primary radiation of a squamous cell carcinoma. The correlation of the radiation-induced vasculopathy with regard to applied radiation dose and time latency is discussed on the basis of published references.

Aortography↗

CT diagnosis of thrombosis of dural sinuses in childhood.

This paper describes the CT findings in five cases of cerebral and cerebellar sinovenous occlusion. Characteristic CT findings are the visualisation of the thrombosed sinuses and veins, known as the "filled triangle" and the "cord sign" on the control scan, and the "empty triangle" with tentorial and gyral enhancement after contrast enhancement. The high incidence of thrombosed internal cerebral veins and superior cerebellar veins with sinus thrombosis in children is remarkable. CT with both control and contrast enhanced scans will probably provide the correct diagnosis in the majority of cases.

Child, Preschool↗

[Sonographic image of cholesterolosis of the gallbladder].

Cholesterolosis is the most frequent cause of polypous space-occupying growths of the gall bladder. Cholesterol polyps are visualised in sonography as usually multiple growths of 2-10 mm size, with abundant echoes and without shadows. The disease pattern is discussed on the basis of 8 sonographic images.

Adult↗

[Liver metastases: sonography or scintigraphy? A comparative prospective study].

In 278 patients with known malignancy a sonogram, scintigram and laboratory examination were done on the same day. The comparison of the examinations revealed nearly the same accuracy for both imaging modalities with 90% for sonography and 89% for scintigraphy. Sonography showed the more uniform results, because scintigraphy had a high percentage of false positive results. The value of both methods as the utility of an additional laboratory examination are discussed.

Female↗

[Metastatic involvement of the breast].

The mammographic spectrum of metastases in the breast is illustrated by 43 cases with histologically confirmed findings. Haematogenous metastases appear as sharply demarcated foci, lymphogenous metastases produce thickening of the skin and reticular thickening of the subcutis and of the glandular tissue. Metastases from systemic haematological disease may appear in nodular or diffuse form.

Adolescent↗

[Therapeutic embolization with polyvinyl alcohol (Ivalon). Clinical experiences].

Polyvinyl alcohol is rigid foam used in pressed or unpressed form for the purpose of embolisation. It is suitable for both micro-embolisation in the vascular periphery and for central vascular occlusion. Polyvinyl alcohol will result in permanent vascular occlusion. Basing on the experience collected with 71 embolizations, the article reports on the technique applied and on the results obtained with craniofacial, thoracic, abdominal, pelvic and peripheral embolisation.

Adolescent↗

[Gastroduodenal Crohn disease--a case report].

A case of gastroduodenal Crohn's disease is presented by describing the acute phase and findings after one year. Typical signs are the localisation in the region of the antrum-pylorus-bulbus, as well as the paving-stone relief pattern and the pseudo-post-Billroth-I sign.

Adult↗

[Transcatheteral embolization with polyvinyl alcohol--technic and experimental studies].

The article presents hardened polyvinyl alcohol foam (PVA) as embolisation material. PVA is well tolerated by the tissue and produces permanent vascular sealing. It is possible to achieve peripheral embolisation of arteries having a diameter of approx. 100 microns, as well as sealing of vessels with diameter of up to 8 mm. Pressed PVA is used for occluding larger vessels. This PVA re-assumes its original shape and dimensions in liquids, depending on their osmolarity and molecular size. Depending upon the pressure exercised, compression and re-expansion can be fourfold to tenfold.

Angiography↗

Osteoscintimetry--a method of semiquantitative evaluation of skeletal scintigrams by use of profiles and a macro function for computer processing.

A computer macro-program was developed for standardized, semiquantitative measurement of radiotracer uptake. The method uses profiles of selectable length, width, and inclination according to the anatomical structures of the pathological and the corresponding healthy region. The ratio of the two curves is calculated automatically and shown as an 'uptake curve'. The essential use of osteoscintimetry is in the follow-up examination if small changes of regional uptake have to be identified. The profile-technique rather than the ROI-technique was selected, because the main benefit of the profile-technique is that the results of follow-up examinations are comparable to previous examinations with a standard deviation of +/-5%.

Adolescent↗

[A computer macro-programme for osteoscintimetry and activity profile in Perthe's disease (author's transl)].

A computer macro-programme has been developed which permits quantitative scintigraphy by means of an activity profile. The slope and width of the profile are variable; a view at right angles to the epiphyseal plate of the femoral head is able to determine activity in the plate and in the epiphysis. Measurements of the abnormal and normal hip produce uptake rates. These indicate to what extent the abnormal femoral head and epiphyseal plate differ from the normal side, with respect to their uptake. The method and results are discussed.

Child↗

[5-year scintigraphic study of children with Perthes disease. Diagnostic evaluation and therapeutic consequences].

The value of bone scintigraphy in the diagnosis and follow-up of Perthes disease has been studied in 179 patients. Amongst 63 patients with Perthes' disease, there were 11 in whom the diagnosis could be made by scintigraphy before there were radiological signs. This enables early treatment to be carried out and leads to a shorter course of the disease and improved end-results. Scintigraphy alone makes it possible to judge the actual state of revitalization of the necrotic femoral head. From this, it is possible to derive the indications for a displacement osteotomy before the radiological signs of a "head at risk" appear.

Adolescent↗