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Biomedical subjects

J Lam

Publications and source records attributed to J Lam.

110 records · Page 7Linked to original sources

Mesoblastic nephroma metastatic to the lungs and heart--another face of this peculiar lesion: case report and review of the literature.

A case of mesoblastic nephroma in a 14-month-old girl who developed consecutive metastases in the lung and the heart is presented. This tumor is considered to be benign and cured by surgery only. Recurrent cases are extremely rare and usually related to unclear surgical margins. Metastatic mesoblastic nephroma has been previously described in only two cases. The present case highlights a new, previously undescribed feature--the ability to metastasize to sites other than lung.

Combined Modality Therapy↗

Ultraviolet-mediated antibiotic activity of species of Compositae caused by polyacetylenic compounds.

A survey of North, Central, and South American composites, and of certain polyacetylenic compounds occurring in them, confirmed that the ultraviolet-mediated antibiotic activity against Candida albicans can be ascribed to the presence of particular polyacetylenes and their thiophene derivatives. Leaves, stems, roots, and achenes were assayed separately. An attempt was made to relate the phototoxic activity of specific compounds to their chemical structures. Most composites tested were not phototoxic against Candida, but many were antibiotic. The antibiotic activity also appears to be caused by polyacetylenes. Of 65 sequiterpene lactones assayed, only a few were found to be antibiotic, and only one, glaucolide G, was phototoxic.

Alkynes↗