Search PubMed⌕ Search

Biomedical subjects

J Laissue

Publications and source records attributed to J Laissue.

At least 55 records · Page 3Linked to original sources
PubMed1979

[Intravascular uterine leiomyomatosis].

Intravascular (intravenous) leiomyomatosis is a rare uterine neoplasm. The unusual growth and extension of histologically benign smooth muscle tumors in vascular channels of uterus and pelvis are cardinal features of the disease. The course of the affection has been benign in the majority of the cases reported in the literature. Clinical and pathologic aspects are briefly evaluated in the context of an example of intravascular leiomyomatosis in a 30-year-old woman.

Adult↗
PubMed1975

Kinetic studies on glial, Schwann and capsular cells labelled with [3H] thymidine in cerebrospinal tissue of young mice.

Neuroglia, capsular and Schwann cell renewal and turnover in the cerebellum, the spinal cord and spinal ganglia have been evaluated in 2-months-old mice. The animals received intraperitoneal injections of [3H] thymidine at 8 hr intervals starting on the 28th day of postnatal life for a period of 30 days and were killed 1 hr after the last injection. Substantial numbers of labelled neuroglial cells but no labelled neurons were observed. Oligodendrocytes of the cerebellum and the spinal cord showed higher labelling indices (19.8% and 18.0%, respectively) than astrocytes (10.0%) and Bergmann's supporting cells (7.2%). The labelling indices of capsular cells in the spinal ganglia and Schwann cells in the spinal roots were 35.8% and 25.8%, respectively. The experiments failed to provide evidence for matrix cell layers in the cerebellum, the spinal cord and spinal ganglia. It may be concluded therefore that glial and Schwann cells in these parts of the nervous system proliferate in situ.

Animals↗
PubMed1975

Hayflick's hypothesis: an approach to in vivo testing.

The experimental evidence relating to the hypothesis of finite cellular life is reviewed. It is emphasized that even if somatic cell production were limited its total potential would have to be vast to provide for extensive cellular regeneration. The actual limit of reproductive cell life would therefore not likely be reached in a normal life-span. It is proposed to test the hypothesis by deliberate exhaustion of stem-cell reserve, and iron-55 cytocide is described as an experimental system that might be applicable.

Animals↗
PubMed1975

Selective damage to erythroblasts by 55-Fe.

The low energy and short range of 55-Fe Auger electrons were utilized in mice to deliver lethal intracellular radiation to iron-incorporating erythropoietic precursors with minimal radiation damage to other bone marrow cells. The ensuing intramedullary, selective erythropoietic death was demonstrated by absolute and differential bone marrow cell counts and by decreased blood uptake of 59-Fe. The decreased number of colony-forming units in spleen colony assay and the decreased ability of tranplanted bone marrow to protect fatally irradiated mice shows that the bone marrow was partially depleted of pluripotent stem cells. These data are interpreted to indicate an increased pluripotent stem cell utilization in response to increased demand for differentiation of stem cells along the erythropoietic pathway.

Animals↗
PubMed1975

Survival of chromium-51-labeled autologous and homologous erythrocytes in goats.

Apparent half-survival time of 51-Cr-tagged caprine erythrocytes after autotransfusion was 8 days. The 51Cr-tagged homologous caprine erythrocytes disappeared from circulation very rapidly, thereby indicating that it is not possible to produce sustained polycythemia in goats by hypertransfusing them with homologous erythrocytes without appropriate matching.

Animals↗