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Biomedical subjects

J L Strife

Publications and source records attributed to J L Strife.

At least 55 records · Page 3Linked to original sources

Nuclear cystography and renal sonography: findings in girls with urinary tract infection.

This retrospective study documents the findings on nuclear cystography and renal sonography of 455 girls who had urologic imaging for a proved urinary tract infection (UTI). Nuclear cystograms were normal in 313 (69%) of 455 patients. Vesicoureteral reflux was seen in 142 patients (31%): six with grade I, 90 with grade II, 43 with grade III, and three with grade IV. Twelve percent of patients with vesicoureteral reflux had renal parenchymal scars. Increasing grades of reflux were associated with an increase in the severity and number of parenchymal scars. Normal renal sonograms were seen in 83% of patients. Abnormalities noted on sonograms included parenchymal scarring in 31 (7%) of the 455 patients, anomalies in 19 patients (4%), mild to moderate dilatation of the renal pelvis and or ureters in 45 patients (10%), and bladder wall thickening in 45 patients (10%).

Adolescent↗

The effects of Le Fort I osteotomy with maxillary movement on articulation, resonance, and velopharyngeal function.

Articulation, resonance, and velopharyngeal function were evaluated before and after Le Fort I maxillary advancement in 16 patients (seven with cleft lip and palate, one with cleft lip only, and eight without clefts). On the postoperative evaluation, seven of 11 patients with preoperative articulation errors showed an improvement in articulation after surgery. Two patients without clefts showed slight changes in nasal resonance, and two patients (one with cleft lip and palate and one with cleft lip only) developed mild nasal emission. Nine patients showed diminished velopharyngeal contact during speech on videofluoroscopic studies. Compensatory changes in velopharyngeal function were also observed, which included velar stretching and lengthening and increased lateral pharyngeal wall movement.

Adolescent↗

Arterial occlusions in neonates: use of fibrinolytic therapy.

For neonates with ischemia of an extremity or extensive thrombosis of the aorta after umbilical artery catheterization, prompt recognition and management decisions are necessary. The cases of eight infants with symptomatic thrombosis who were treated with fibrinolytic agents were retrospectively reviewed to study means of diagnosis and response to therapy. Peripheral thrombosis was seen in two otherwise healthy infants; fibrinolytic therapy produced complete lysis in one and partial lysis in the other. The six infants with central thrombosis presented with low Apgar scores and multiple clinical problems; umbilical catheters were already in place. To assess the clot, real-time sonography was performed in all six patients, and umbilical arteriograms were obtained in five. Fibrinolytic therapy produced complete lysis of clot in five of the six infants. The one death occurred in a premature infant in whom a large intracranial hemorrhage developed 6 hours after institution of therapy.

Aorta, Abdominal↗

Evaluation of a low-dose neonatal chest radiographic system.

A new low-dose chest radiographic system for use in the neonatal nursery was evaluated. This test system, composed of a Du Pont Kevlar fiber-front cassette, Quanta fast-detail screen, Cronex 4L film (wide latitude), and additional yttrium filtration (0.1 mm), reduced the radiation dose in neonatal chest radiography by 69% (0.9 vs 2.9 mrad [0.009 vs 0.029 mGy]) as compared with a conventional system without added yttrium filtration; the thyroid dose was reduced by 76% (0.9 vs 3.7 mrad [0.009 vs 0.037 mGy]). The cumulative dose reduction was achieved through a combination of factors, including (1) beam hardening by the added yttrium filter, (2) increased X-ray transmission through the Kevlar cassette, and (3) a fast film-screen combination. Scatter radiation at distances of 1 and 6 ft. (0.3 and 1.8 m) was negligible for both systems. Image sharpness was compared for the conventional system with and without added yttrium filtration and for the Kevlar system with yttrium. Although sharpness of bony detail was unchanged by adding yttrium filtration to the conventional system, a decrease in sharpness was noted with the Kevlar system. Because image sharpness was affected in the test system, we are not using the Kevlar-Cronex 4L system for mobile chest radiography in the neonatal intensive care unit, despite dose reductions. However, further study is recommended to determine if there is a slower film-screen combination with yttrium filtration that will not degrade image sharpness.

Evaluation Studies as Topic↗

Upper airway and tracheal obstruction in infants and children.

The radiologist plays a key role in the diagnosis of airway obstruction in children. Most diagnoses are made on the basis of plain films. In more complicated or complex entities, CT and MRI give excellent anatomic detail in defining the airway, associated soft tissues, and vascular relationships.

Airway Obstruction↗

Urography and voiding cystourethrography: findings in girls with urinary tract infection.

The voiding cystourethrogram and excretory urogram have been considered essential parts of the evaluation of girls with urinary tract infections. To evaluate the usefulness of these procedures, 523 examinations in girls with urinary tract infections were reviewed retrospectively. The major finding on voiding cystourethrograms was vesicoureteral reflux, occurring in 36% of the children. Of the total group, 8% had excretory urographic evidence of parenchymal scarring. Higher grades of reflux were associated with an increase in parenchymal scarring. All urethras were normal, and only one paraureteral diverticulum was identified. Bladder emptying was incomplete in 46% of the patients. Ovarian radiation doses were measured with "low-dose" and standard systems. On the basis of this study, traditional approaches to the standard workup are questioned.

Adolescent↗

The duplex collecting system in girls with urinary tract infection: prevalence and significance.

The association between vesicoureteral reflux, parenchymal scarring, and urinary tract infection in children with nonduplicated collecting systems is well known, but similar data for children with duplex systems are sparse. The purpose of this study was to determine the prevalence of duplex anomalies in girls with a history of urinary tract infection and to compare the prevalence of associated reflux and parenchymal scarring to that found in girls with nonduplex systems. Voiding cystourethrograms and excretory urograms of 560 girls referred for evaluation of urinary tract infections were reviewed retrospectively. Duplex collecting systems (complete and partial) were found in 8%. Vesicoureteral reflux was seen in 69% of complete duplex systems and in 22% of partial duplex systems. Parenchymal scarring was evident in 17% of those girls with complete duplication and in 6% of those with incomplete duplication. The statistics for girls with partial duplication were very similar to those for girls with urinary tract infection and nonduplex systems. These data indicated that girls with partial duplex systems clinically appear similar to those girls with anatomically normal systems. Girls with complete duplex systems had a higher prevalence of vesicoureteral reflux and associated anomalies, indicating a need for closer follow-up and/or surgical intervention.

Child↗

Vascular rings: MR imaging.

The purpose of this study was to assess the utility of MR imaging in identifying anatomic features of vascular rings. MR imaging of the thorax was performed in five consecutive children with symptoms and findings of vascular rings on barium esophagography. The diagnoses were subsequently proved at surgery and/or angiography. Preoperative definition of the anatomy was adequate and accurate in each case. Our preliminary experience with MR imaging in five patients with vascular rings suggests that this technique is an excellent alternative to angiography when further anatomic delineation of the abnormality is required.

Aorta, Thoracic↗

Multiple enteric duplications in an infant.

Duplications of the alimentary tract are an uncommon entity in children. The occurrence of multiple duplications in different segments of the gastrointestinal tract has been reported, but it is unusual. This is a report of an infant who had esophageal, gastric, and duodenal duplications.

Abnormalities, Multiple↗

Normal left atrium: appearance in children on frontal chest radiographs.

The right lateral border of the left atrium can be seen in the anteroposterior radiographs of healthy children. Five hundred forty-three frontal radiographs, mostly of children, were reviewed, and the right lateral border of the left atrium was visualized in 30%, although it was very prominent in only 2.5% of cases. In a comparison of frontal angiocardiograms with plain chest radiographs, the shadow was demonstrated to be the lateral or inferior wall of the left atrium. Entities that simulate the left atrial shadow are presented, and ways to distinguish normal appearance from abnormalities are discussed.

Adolescent↗

Interventional genitourinary radiology in children: a review of 61 procedures.

Forty-nine children underwent 61 interventional uroradiologic procedures. These included percutaneous nephrostomy, internal ureteral stenting, ureteral stricture dilatation, perirenal abscess drainage, and percutaneous removal of renal calculi. Of the 61 procedures, 60 (98%) were technically successful. Of the 60 successful procedures, 24 (40%) were considered "definitive," 33 (55%) favorably "altered the course," and 3 (5%) "failed" to have any beneficial effect. Technical success at minimal risk can be achieved in even the smallest patients by modifying equipment and by attending to the special needs of the pediatric patient.

Adolescent↗