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Biomedical subjects

J L Quinn

Publications and source records attributed to J L Quinn.

14 recordsLinked to original sources

Unusual bone scan presentation in osteomalacia: symmetrical uptake--a suggestive sign.

Osteomalacia presents radiographically as deossification, coarsening of the trabecular pattern, and pseudofractures. Contrary to the usual bone scan manifestation of osteomalacia, consisting of a generalized increase in periarticular radionuclide accumulation and pronounced costochondral junctional uptake, this report describes an unusual bone scan presentation with negative radiographic studies showing only some deossification. Symmetric distribution of the focal lesions is considered a suggestive sign of osteomalacia.

Aged

Improved dynamic and static imaging of abdominal aortic aneurysms.

The authors describe a technique for rapid, convenient in vivo labeling of circulating erythrocytes with 99mTc and the application of this technique to the evaluation of abdominal aortic aneurysms. Dynamic perfusion images and equilibrium blood pool images were obtained in 9 patients with documented aneurysm, and 7 of them indicated an aneurysm on the radionuclide study.

Aorta, Abdominal

"Hot spot" on hepatic scintigraphy and radionuclide venacavography.

Seven patients showing a localized area of increased uptake (hot spot) on 99mTc sulfur colloid liver scans are described. Four also had dynamic studies. In five patients the hot spot was associated with superior vena caval obstruction, in one it was associated with inferior vena caval obstruction, and in one with a hepatoma. Although a hot spot on static liver images usually indicates superior vena caval obstruction, the addition of radionuclide venacavography is recommended to confirm the diagnosis. A hot spot in the liver area in a radionuclide venogram of the lower limbs suggests inferior vena caval obstruction with collaterals via the liver.

Carcinoma, Hepatocellular

Myocardial uptake of thallium-201 augmented with bicarbonate: concise communication.

Sodium bicarbonate was used to enhance the myocardial concentration of Tl-201 in rabbits and dogs. Organ distribution studies in rabbits and in vivo imaging in dogs showed a 1.5-2 fold increase in myocardial Tl-201 concentration in bicarbonate-treated animals as compared with matched controls. Image improvement was noted, with threefold enhancement of myocardium-to-liver ratios. The results suggest that a similar improvement may be possible for clinical myocardial imaging.

Animals

Scanning techniques to assess thyroid nodules.

Despite its nonspecificity, the thyroid scan remains an important diagnostic aid in the evaluation of the patient with a solitary thyroid nodule. Dual radionuclide thyroid imaging using 99m-Tc pertechnetate and 123-I offers useful information than either alone. The role of complementary diagnostic modalities using ultransonography and thermography looks promising but is as yet unclear.

Adult

An animal model of radionuclide venography.

Experimental venous thrombi were created in 19 dogs, using either thrombin or sodium morrhuate. Eighteen thrombi (95%) were identified by radionuclide venography; however, an 85% false-positive rate was found when nonoperated limbs were studied. The models employed were considered unsuitable for studying the accuracy of labeled particles in diagnosing deep venous thrombosis for the reasons discussed in the text.

Albumins

Rebuttal to TV show: "coffee, tea or radiation".

On 22 October 1974, CBS News presented a segment "Coffee, Tea or Radiation" on its program "Magazine". The program focused on the hazards of transporting radioactive materials by common carrier, especially by air. The presentation provoked strong reaction among some knowlegeable individuals. The text o this article is a letter sent by the author to Perry Wolf, CBS News, New York. A copy was made available to the American Society of Non destructive Testing through Walter P. Peeples, Jr., president, Nuclear Environmental Engineering, Inc., Houston, Texas.

Humans