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Biomedical subjects

J L Moreno

Publications and source records attributed to J L Moreno.

At least 37 records · Page 2Linked to original sources

[Migration from Southern Italy to Argentina: Calabrians and Sicilians (1880-1930)].

"The study analyzes Italian emigration to Argentina from Sicily and Calabria between 1880-1930, compared with out-migration flows from Piedmont. The concepts of cultural patrimony and of migratory strategy are used to measure the different potentials and job opportunities in the Argentinean labor market as well as in the Italian context for those returning home. Considering the high proportion of returnees, a positive or negative correlation between region of origin and of destination can be proposed. Southern Italians indicate a more permanent settlement. The authors conclude that the Argentinean society in its Italian component is the result of Southern rather than Northern influences." (SUMMARY IN ENG AND FRE)

Americas↗

[Placental transfer of tetanus antibodies and protection of newborn infants].

Total IgG and tetanus antibodies were evaluated in 2 series of mother-child pairs: 50 in Paris and 134 in Africa. All pregnancies had been normal and birth weights greater than 3 kg. Cord blood mothers tetanus antibodies ratios were 1.5 in Paris and 0.98 in Libreville (p less than 0.01) respectively. Some African children were not protected, either due to the lack of response of their mothers to immunization (2.2%) or to an insufficient antibodies transplacental transport (2.9%), or to the lack of immunization of mothers (5.9%). On the contrary, all European children were protected, in spite of low maternal antibody levels. Likewise, in Paris cord blood IgG level was 12.24 g/l vs 9.42 in mothers (cord blood/mother ratio: 1.34) and in Africa 18.4 g/l in cord blood and 22.3 g/l in mothers (cord blood/mother ratio: 0.88; p less than 0.01). The correlations between maternal IgG levels and placental transfer rates indicate that the transplacental active transfer is limited by common high IgG levels in Africa, thus contributing to a decrease in protection of neonates, especially against tetanus in which humoral responses predominate.

Adolescent↗

[A case of entomophthoromycosis caused by Conidiobolus coronatus].

The authors report a case of entomophthoromicosis caused by Conidiobolus coronatus, a saprophytic fungus that belongs to the class Zygomycetes (Phycomycetes in the past). Our patient was from a rural area. The paranasal sinuses had been drained surgically and a polyp was removed from his nasal cavity. He had a deformity in the face and nasal obstruction. His general condition and immunological status were normal except for epistaxis since childhood. The diagnosis was made clinically by the appearance of the lesion and confirmed by the mycological and histopathological findings. The therapeutic response was slow but with total resolution of the lesion.

Adult↗

[The first isolation of Mycoplasma pneumoniae in Panama].

Mycoplasma pneumoniae was isolated for first time in Panama and identified from a nine years old girl with pneumonia. SP4 medium was used to isolate the bacteria. Confirmatory serological results were obtained by indirect immunofluorescence and were also suggested by the presence of cryoagglutinins in the sera of this patient. DNA hybridization tests (Gen--Probe) were carried out.

Child↗

[Perinatal mortality at the Hospital Center of Libreville (Gabon)].

A study of the work carried out in the obstetrical department during the years 1985, 1986 and 1987 shows there was a corrected perinatal mortality of 32.61 per 1,000. This involved 776 deaths out of 23,980 births of babies weighing 1,000 g. or more. Research as to the causes showed that the largest reasons for these deaths were maternal and fetal infections (28.9% of the aetiology of perinatal mortality). In 35.1% of cases there was obstetrical trauma leading to intrapartum anoxia and prematurity was responsible for 63.7% of deaths associated with other causes. These figures can be reduced if there is better antenatal care in Maternity and Paediatric Centres with teams that are competent and that are properly trained, and on the other hand the delivery rooms are rebuilt in such a way as to make it possible to supervise labours and deliveries and to look after the newborn children immediately problems involving newborn care are found.

Cause of Death↗

Hereditary branchial myoclonus with spastic paraparesis and cerebellar ataxia: a new autosomal dominant disorder.

We report a family with branchial myoclonus, spastic paraparesis, and cerebellar ataxia in which six members were affected in two generations and the inheritance appeared to be autosomal dominant. Age at onset ranged from 40 to 50 years. Rhythmic myoclonus involving the palate, pharynx, larynx, and face was followed by truncal ataxia and spastic paraparesis in most patients. CT and MRI revealed mild atrophy of the cerebral and cerebellar cortex and severe atrophy of the medulla and spinal cord. The pons appeared normal and the olives not hypertrophic. CSF studies revealed severe reduction of the serotonin metabolite 5-hydroxyindoleacetic acid. Treatment with 5-hydroxytryptophan and carbidopa at highest tolerated dose mildly improved ataxia but did not modify the myoclonus. Treatment with anticholinergics, benzodiazepines, phenytoin, valproate, carbamazepine, and baclofen was unsuccessful. The clinical symptoms were progressive, leading to death or severe disability 5 to 10 years after the onset of the disease.

Adult↗

[Interaction between Salmonella and Schistosoma intercalatum].

Close interactions between salmonellae and Schistosoma intercalatum were demonstrated by a study of 118 children conducted at Libreville, Gabon. Bilharziasis, confirmed by rectal biopsy, was present in 76% of children hospitalized for typhoid-like salmonella septicaemia, as against 38% of controls of the same age living in the same district (P less than 0.001). Although the clinical symptoms were typical of typhoid fever, with stupor, myocarditis or leucopenia depending on the cases, the germs responsible in 26 out of 42 cases were salmonella species regarded as minor. Finally, the salmonella infection was clinically prolonged by bilharziasis in 1 out of 3 patients. It would therefore appear that salmonella adheres to the wall of S. intercalatum as to that of other schistosoma species, and that both infections must be treated concomitantly.

Adolescent↗

[Incurable keratitis and chronic palmoplantar hyperkeratosis with hypertyrosinemia. Cure using a tyrosine-restricted diet. Type II tyrosinemia].

One should henceforth systematically search for hypertyrosinemia which, too often, goes unrecognized for years, in patients presenting chronic keratitis associated with palmar and plantar hyperkeratosis. As a matter of fact, this highly crippling disease may be cured with an appropriate diet and the diagnosis, once suspected, is easily confirmed by simple investigations.

Adolescent↗

[Palmoplantar keratosis associated with keratitis: hereditary hypertyrosinemia treated by diet].

The authors report the cases of two unrelated children 16 and 5 years of age respectively, affected with hypertyrosinaemia type II. This condition is characterized by palmo-plantar hyperkeratosis associated with a herpetiform keratitis. The diagnosis is based on the finding of hypertyrosinaemia and hypertyrosyluria, and may be confirmed by their biopsy findings of a cytoplasmic tyrosine amino-transferase deficiency. It is a hereditary autosomal recessive disease. A low phenylalanine and tyrosine diet produced a spectacular improvement but the ocular complications could have been avoided by an earlier diagnosis.

Adolescent↗