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Biomedical subjects

J L Mijan Ortiz

Publications and source records attributed to J L Mijan Ortiz.

3 recordsLinked to original sources

[Oxalate: its role in lithogenesis and composition of calcium oxalate lithiasis].

UNLABELLED: A prospective study was conducted on 374 patients with urinary lithiasis, aiming to analyze the participation of oxalate in the lithogenesis and composition of the calcium oxalate calculi, alone or associated to other factors. METHODOLOGY: Metabolic urinary study of the patient and analysis of calculi with infrared spectrography and optical microscopy. RESULTS: 26.3% patients had hyperoxaluria and 77.5% of the calculi contain calcium oxalate; these are 167 cases of calcium oxalate, 110 of oxalate and calcium phosphate and 13 cases of mixed calcium oxalate and uric acid lithiasis. 43.4% patients with pure monohydrate calcium oxalate calculi have hypercalciuria, 22.6% hyperoxaluria and 19% hyperuricosuria. Dihydrated calcium oxalate calculi are related to high hypercalciuria in 65% cases and to significant hyperoxaluria in 35% cases. 45% patients present a single lithogenic factor, either hypercalciuria (49.6%), hyperoxaluria (20.6%), hyperuricosuria (13.74%), hypocitraturia (9%), urinary infection (1.5%), A.T.R. (2.25%) or acid oliguria (3%).

Calcium Oxalate↗

[Examination of Doppler color ultrasound in patients with ESWL].

Although treatment by shock waves has been proven useful in destroying calculi, it is not free from complications and may cause lesions to the kidney whose importance has not been completely elucidated. The present study utilized color Doppler US to determine the changes produced by ESWL on the kidney and its vessels in particular. The results achieved by Doppler evaluation of 25 patients immediately before ESWL, 2, 7 and 30 days post-ESWL show an increased resistance index 2 days after treatment which tended to return to normal at 30 days. We discuss the different results obtained depending on stone location and the complications.

Adult↗

[Experimental oxalic lithiasis. Crystallographic study].

An intense oxalo-calcium nephrocalcinosis can be produced in rats, by the experimental use of substances such as glyoxylic acid and ethylene-glycol which can be transformed into oxalic acid within the organism. So can it be possible to make the crystallographic study of the crystal precipitations induced after administering those substances. For that purpose we have used a total number of 24 rats to which the above mentioned substances were administered, at different doses and by different methods. Thus, an intense parenchymatous crystalline precipitation was obtained, which allowed us to study the structure of those crystals by means of C. Zeiss photomicroscope. The results obtained in the different groups studied were similar. A much higher presence of crystals of monohydrate calcium oxalate was observed, although crystals of dihydrate were also found, although some of them under clear process of transformation into monohydrate form.

Animals↗