Search PubMed⌕ Search

Biomedical subjects

J L Magne

Publications and source records attributed to J L Magne.

At least 37 records · Page 2Linked to original sources
PubMed1996

[Traumatic rupture of the bladder. Apropos of 26 cases].

26 patients were seen with ruptured bladders at Grenoble Hospital during the last 15 years. Pelvic fractures were present in 95% of the cases. Bladder injuries were extraperitoneal (58%), intraperitoneal (27%), intraperitoneal and extraperitoneal (15%). Patients were hospitalised in Urological Department (40%) or General Surgical and Intensive Care (60%). All patients with intraperitoneal bladder injury, 61% with extraperitoneal ruptures were treated by surgical repair. 4 patients died, secondary to visceral associated injuries.

Adult↗
PubMed1996

[Vascular surgery and organ transplantation].

Among the recent advances in organ transplantation, the introduction of cryropreservation fluids in 1989 has allowed routine protection against ischemia over prolonged periods. There remain however several obstacles which can compromise graft survival and consequently lead to second transplantations and increased organ demand. Vascular complications are one of these complications. In many cases, close collaboration between transplantation surgery and the vascular surgery teams could reduce the number of problems. The aim of this work was to study situations in which collaboration could be useful. There are three areas of particular interest: kidney transplantations, liver transplantations and obviously, multiple organ transplantations.

Humans↗
PubMed1996

[Chronic venous insufficiency 7 to 10 years after partial vena cava interruption with a clip].

In order to test the responsibility of inferior vena cava clips in post thrombotic venous disease, we performed a comparative retrospective study 7 to 10 years after vena cava interruption by clip. Patients were compared with patients matched for sex, age, and prior deep vein thrombosis (same period and same localisation) but without inferior vena cava partial interruption. The results show that 1) functional complaints were significantly higher in the vena cava clip group; 2) valvular incompetency, in the initially thrombosed leg, (tested by scanning duplex) was not different in the two groups: 3) inversely, on the other leg, valvular incompetency was greater in the vena cava clip group. Furthermore this valvular incompetency was principally located at a femoral level, suggesting that the vena cava clip may induce backward thrombosis; 4) complications were independent of vena cava thrombosis.

Adult↗
PubMed1995

[Prediction of respiratory complications after surgery of the abdominal aorta].

The most frequent type of complication in patients undergoing aortic surgery is respiratory. Preoperative lung function (PFT) and arterial blood gas measurement (ABG) are often carried out to assess the risk more precisely. The aim of the present retrospective study was to determine which value of lung function test could identify patients who developed such complications. "Receiver Operating Characteristic" (ROC) curves and the area beneath the curve for the diagnosis of respiratory complications were calculated for each variable of PFT and ABG. The greatest Youden index for each variable was chosen as indicative pulmonary function criterion of increased risk of pulmonary complications. One hundred and ninety-five patients (age: 65 +/- 10 years) were included. Respiratory complications occurred in 15% of patients. Respiratory complications increased from 12% if the vital capacity (VC) was > or = 77% of the predicted value to 35% if the VC was < 77% (P = 0.002), and from 10% if the FEV1 was > 76% to 34% if the FEV1 was > or = 76% (P = 0.0005). A decreased PaO2 or increased PaCO2 was not correlated with an increased incidence of respiratory complications. Length of stay in ICU or in hospital were increased when VC or FEV1 were low. Frequency of pulmonary complications was 9% in patients without PFT abnormalities, 16% in patients with either diminished VC or FEV1 and 35% in patients with both lowered VC and FEV1. However, all the areas under the ROC curves were < 0.7 and the sensitivity of the different variables was low. It is concluded that routine preoperative PFT and ABG cannot predict respiratory complications after abdominal aortic surgery.

Aged↗
PubMed1995

[Partial interruption of the inferior vena cava using a Greenfield titanium percutaneous filter. Present indications and evaluation].

We report a prospective study of 39 patients who presented thromboembolic disease (TED) treated by partial interruption of inferior vena cava (PIIVC) with Greenfield Titanium filter. We observed 2 recurrent pulmonary embolisms, 1 symptomatic deep venous thrombosis and 2 asymptomatic filter thrombosis. With 1 year follow up, the survival probability is of 85%. Concerning the 12 last years evolution in our hospital, we note that the approach of TED diagnosis and treatment by a central, specialised team within the hospital care structure has lead to a reduction in the number of severe cases of TED, and consequently of PIIVC. So the use of percutaneous filters has not lead to an increase in the real rate of PIIVC performed but to a decrease (21% of patients with TED in 1982 vs 8% in 1993).

Adult↗
PubMed1995

Partial interruption of the inferior vena cava: ten-year evolution in protocols at Grenoble University Hospital. Study of 621 patients.

An evolution in protocols regarding indications and modalities for Partial Interruption of the Inferior Vena Cava (PIIVC) on 621 patients at Grenoble University Hospital is reported and the influence of new methods in diagnosis (vascular sonography) and therapy (percutaneous filters) is assessed. This comparative study covers the intervals from 1982-1984 (Period A - 333 patients), and 1989-1991 (Period B - 288 patients). The percentage of patients with venous thromboembolic disease who underwent PIIVC clearly decreased (21.8% in period A vs. 13% in period B, p < 0.01). The incidence of what are currently miscalled "prophylactic", but are in fact adjunctive indications also diminished (115 patients in period A, or 34.5% of the PIIVC cases vs. 60 patients in period B, or 20.8% of the PIIVC cases, p < 0.05). There was a reduction in the use of Miles caval clips (59 patients or 17.7% for period A vs. 34 patients or 11.8% for period B, p < 0.05). Although there has been an increase in the use of percutaneous caval filters, the use of percutaneous filters has not lead to an increase in the real rate of PIIVC performed by an Angiology Unit with a large experience in the diagnosis and follow-up of patients with venous thromboembolic disease.

Combined Modality Therapy↗
PubMed1994

[Sub-adventitial arterial cysts of the popliteal artery. Results from the vascular group of AURC].

A retrospective multicentric study conducted by the vascular group of the AURC (University association of surgical research) included 36 sub-adventitial cysts of the popliteal artery. This is a rare cause of claudication in the young male and usually involves the adventitia of the arterial wall. There is usually only one localization. Echography of the cyst may wrongly suggest partial thrombosis of a popliteal aneurysm. Angiography and CT scan provide the correct diagnosis. The results of surgical treatment were analyzed after a follow-up ranging form 3 months to 20 years (mean 9 years). The reports in the literature confirm that these are rare lesion of a poorly understood origin (congenital or acquired?). Simple complete surgical excision gives excellent results with the exception of initially complicated forms which require resection and grafting.

Adolescent↗
PubMed1994

[Popliteal aneurysm and leg ischemia: surgery first].

The treatment of symptomatic popliteal aneurysms is debated should local fibrinolysis or surgery first be used first? The authors report their experience in the treatment of 90 popliteal aneurysms in 66 patients. In this series were only examined those aneurysms with either acute ischaemia 12 (27%) or sub-acute ischaemia 21 (45%). The treatment of those cases with acute ischaemia was surgical for all, allowing salvage in all cases. Sub-acute ischaemia was treated with either: a surgical bypass with exclusion of the aneurysm in 7 cases, or lumbar sympathectomy in 7 cases, or medical treatment in 6 cases or local fibrinolysis for distal ischaemia in one case only. There was no peri-operative mortality, only one amputation was required (5%) (J Mal Vasc 1994; 19, Suppl. A: pages 150-153).

Adult↗
PubMed1994

[Ostial stenosis of the renal arteries: results of surgery].

Surgery and percutaneous balloon are two contrasting methods for the treatment of renal artery stenosis. Surgical revascularizations offer excellent long term results with a 70% to 90% five year patency rate wherever the location of the lesion on the renal artery. Long term results of transluminal angioplasty are strongly correlated with the anatomo-radiological features of the lesions. From their own experience and after a literature review, the authors conclude that: For lesions located on the trunks of the renal artery, results of surgery and transluminal angioplasty are equivalent. For lesions involving the ostium of the renal artery, the failure rate is high and restenosis are frequent with angioplasty. In that case, surgery is a proper choice which offers better immediate and long term results.

Arteriosclerosis↗
PubMed1992

[Diffuse bronchomalacia after double lung transplantation. Thoughts apropos of a case].

A 40 year old woman suffered from respiratory insufficiency (arterial PaO2 = 47 mmHg) because of a chronic beryllium intoxication. On 6th June 1990, she underwent double lung transplantation with cardio-pulmonary bypass. Each lung was separately implanted via an extra-pericardial approach, and both bronchi were anastomosed at the hilum. On the seventh post operative day, a severe bilateral bronchial ischemia was noticed (black mucosa). Few weeks later, a diffuse bronchomalacia was noticed in the proximal and distal parts of both bronchial trees. To our knowledge, such a bronchial post-ischemic complication has never been reported. The explantation could be several added causes: imperfect preservation of the lung during harvesting, post operative pulmonary oedema, and operative use of an antifibrinolytic agent (aprotinin).

Adult↗
PubMed1990

[Acute aortic dissection and peripheral ischemia. Diagnostic and therapeutic problems. Remote control using nuclear magnetic resonance].

This study concerns 7 cases of acute aortic dissection associated with visceral and/or lower limb ischemia. Only those cases are included which raised diagnostic and therapeutic problems. Patients were excluded who had purely angiographic involvement of an aortic branch and minor rapidly resolving ischemic syndromes. Five of the 7 patients presented type B (type III or distal) and 2 type A (type I or proximal) dissection. All patients received anti-hypertensor medical treatment. All but one had undergone surgery at least once at the acute stage. Five had been followed up and monitored by magnetic resonance imaging (MRI). One type A and 4 type B dissections were thus reviewed between the 15th month and the 9th year. Diagnostically, aortography was found to be inaccurate twice because of incomplete exploration of the thoracoabdominal aorta. Therapeutically, a case of intraoperative death occurred during replacement of the ascending aorta. Thus, out of the 6 patients who survived the acute stage, 4 are alive and asymptomatic, one has been lost sight of and the other died in year 5 after surgery for chronic dissecting aneurysm of the aortic arch. Among the 5 patients examined by MRI, 4 presented aortic ectasia, chronic dissecting aneurysm of the aortic arch and/or a descending aorta with a diameter between 45 and 65 mm. The patient with subnormal aortic diameter had his ascending aorta replaced (the follow-up period at this writing is only 27 months). Among 3 patients who were examined twice, one showed improvement after a year's interval, with a 5-mm increase in the caliber of the dissected aorta.(ABSTRACT TRUNCATED AT 250 WORDS)

Acute Disease↗
PubMed1989

The femoral artery and flexion of the hip joint.

The behavior of the femoral a. when the hip joint passes from the position of extension to the position of flexion at 90 degrees was studied in 13 cadavers, using several methods: anatomic sections, arteriographies or vascular casts. The modifications of the direction and shape of the femoral a. were assessed in the frontal and sagittal planes. They result from a movement combining flexion and torsion of the femoral a. on its axis at 2 different points in its course. The change of direction of the artery in the sagittal plane is the most obvious modification. It corresponds to the displacement and to the inversion of an angle of 45 degrees on the course of the artery. This angle is situated below the level of the inguinal ligament when the hip joint is in extension and above the sartorius m. when it is flexed to 90 degrees. If these modifications are produced in a similar manner in the living subject, they would seem to correspond to the best possible functional adaptation of the femoral a. They may be involved in the genesis of prosthetic aneurysms.

Blood Vessel Prosthesis↗
PubMed1989

[Intraoperative nitroglycerin: value of determining individual doses: (surgery of the abdominal aorta)].

Thirteen patients requiring infrarenal aortic clamping were studied during flunitrazepam, fentanyl, pancuronium and nitrous oxide anaesthesia. Each awake patient was submitted to a volume loading test to determine the haemodynamic status and his optimal left pre-load. Anesthetic induction was well tolerated. Nitroglycerin was administered by continuous infusion before aortic clamping and we determined the dose necessary to decrease the systemic vascular resistance by 20 per cent. This dose was very variable and needed to be increased in five of 13 patients at the time of clamping. With nitroglycerin, we noticed no significant alteration of MVO2 at clamping. Volume loading allowed good stability at declamping.

Aged↗
PubMed1989

[Heterotopic hepatic transplantation in fulminating hepatitis].

Based on a rare case of heterotopic hepatic transplantation (HHT) carried out in a 24 year old woman for fulminant hepatitis of viral origin, the authors present the technique used and the principal post-operative events (rejection, resistant large volume ascites and the clinical course for the liver itself). They discuss the rarity of success in this type of graft, where the causes of failure in man have not been entirely elucidated: the venous pre-existing portal hypertension is probably a very unfavorable factor. The place of this particular type of HHT in cases of acute severe hepatic failure is then proposed: this may produce a smaller operative insult than orthotopic transplantation and, in this respect, deserves consideration when advanced hepatic encephalopathy is present, notably due to delay in finding a suitable graft.

Adult↗
PubMed1988

Stability of performances of vascular prostheses retrospective study of 22 cases of human implanted prostheses.

Twenty-two cases of vascular graft failures (thrombosis, pseudoaneurysm, dilation, infection) were investigated by means of physicochemical, histological, and ultrastructural studies. A general decrease of mechanical resistance to stress of the prostheses was observed. Its magnitude ranged from 2 to 75% of the values of identical virgin prostheses and there was no relation with the duration of implantation. In addition to the breakage of yarn filaments (SEM), migration of fiber debris (histology) was observed in 7 cases. The structure of the polyester molecule had evolved after implantation. A decrease of crystallinity (x-ray diffraction and differential scanning calorimetry) was noted. These observations raise the question of the established stability of vascular prostheses and emphasize the need for further investigations in human graft retrieval programs.

Biocompatible Materials↗
PubMed1987

[Chronic venous insufficiency and microcirculation. Physiopathologic and therapeutic reflections].

In patients with chronic venous insufficiency, tissular damage occurs as a consequence of microcirculatory disturbances. Venular distension, venulo-arteriolar reflex and probably valves in collecting venules are the only microcirculatory protective mechanisms against venous pressure overload. Edema is primarily a consequence of increased capillary hydrostatic pressure. However, the increase of endothelial macromolecular transport and a true lymphatic microangiopathy are important contributive factors. Venous ulceration is hypoxic although the amount of total blood flow is normal in the surrounding tissue. Several hypothesis were proposed for explaining this nutritional steal: arterio-venous shunt vessels have never been shown consistently, peri-capillary fibrin deposition might block oxygen diffusion, and last but not least, the abnormal geometrical arrangement of the capillary bed is facilitating functional shunting. On a therapeutic point of view, behind the classical hemodynamic therapy, the microvascular approach to chronic venous insufficiency supports the use of lymphatic manual drainage for controlling edema and rheologic therapy for improving skin capillary perfusion.

Humans↗