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Biomedical subjects

J L Lamarque

Publications and source records attributed to J L Lamarque.

At least 37 records · Page 2Linked to original sources

[New techniques of thyroid medical imaging. Value and limitations in the exploration of isolated thyroid nodules].

The exploration of thyroid nodules deals mainly with the problem of detection of malignancy. Except in the cases of characteristic clinical situations which suggest at once malignancy, classical investigations offer mostly an insufficient approach including erroneous conclusions. Scintigraphy, whose morphological definition remains limited, can miss non- or hypofixing lesions. Pharmacological tests of nodule reduction by suppression of thyreostimulin do not provide specific informations. Fine needle- biopsy cannot absolutely exclude malignancy, depending too much of the sites of punction and of the difficulties of cytological analysis. Echography brings an important progress in the precision of thyroid volume, nodules counting and gross connections. The liquid or solid characterization is an important echographic information as well. Tomodensitometry provides useful data in the retrosternal and retrotracheal areas. The connections with aerodigestive tract are more clearly pointed out and the presence of metastatic nodes as well. Magnetic resonance imaging gives further information because of the ability of multiple longitudinal slices, and of the trial of a tissular characterization from signal analysis and ultrastructural macroanatomic study. Additive precisions will be likely in the future by a more accurate determination of criteria of malignancy. The complementarity of magnetic resonance imagery and fine needle-biopsy should lead to a more frequent use of these investigations before the decision of surgical removal.

Diagnostic Imaging↗

[Role of imaging in the exploration of the adrenal glands].

Currently, the major method of adrenal gland imaging is computed tomography. This method allows demonstration of normal adrenals and the diagnosis of adrenal masses (if these are greater than 1 cm in diameter). The examination should be directed by clinical signs and known laboratory investigations. Computed tomography is therefore the first line investigation to perform. Certain lesions may be better demonstrated by other methods: MRI and MIBG scintigraphy offer a greater specificity in the investigation of pheochromocytomas. In addition, scintigraphy can identify possible ectopic tumours or recurrences. Selective catheterisation of the adrenal veins allows aldosterone and cortisone secretions to be assayed. There remains the problem of the incidental finding of adrenal masses in either an asymptomatic patient or in the context of investigation of spread of a know cancer. These lesions may benefit from diagnostic percutaneous guided biopsy.

Adrenal Gland Neoplasms↗

[Calcifying muscular metastases of colonic origin. Apropos of a case localized in the psoas muscle].

A case is reported of calcifying metastases of colon origin localized to psoas muscle. Emphasis is placed on the effectiveness of CT scan and MR imaging and the rarity of this localization. The presence of intra-lesional calcifications as described in hepatic metastases raises the question of the etiopathogenic mechanism and the predictive value of the detection of a calcified mass during the course of colon adenocarcinoma.

Adenocarcinoma↗

[Pseudotumoral retroperitoneal tuberculosis. Apropos of a case].

A case is reported of pseudotumoral retroperitoneal tuberculosis with invasion of left supraclavicular glands. Relative diagnostic efficacy of ultrasound and CT scan imaging is discussed as well as the differential diagnosis of this exceptional lesion. Exploratory procedures suggested with this type of picture are ultrasonography. CT scanning and possibly guided needle puncture biopsy to avoid surgical exploration. The value of the scanner for follow up review of results of antituberculosis treatment is emphasized.

Antitubercular Agents↗

[Muscular metastases. Uncommon manifestation of cystadenocarcinoma of the pancreas].

The authors report the detection of a cystadenocarcinoma of the caudal pancreas developed by muscular metastasis. They insist on the rarity of that type of localization to distinguish from the lesions of steatonecrosis. In the check-up of the developing metastasis, this observation bears out the interest of the C.T. of first meaning which allows an approach of lesional characterization owing to the analogies of structure existing between the causal pancreatic lesion and its muscular and hepatic metastasis.

Aged↗

Breast pathology in MRI. First results.

The authors present the first results of the assessment of MRI (0.35 T) with adapted surface reel in the exploration of mammary pathology in 90 cases. On a morphological level, MRI permits a new analysis of signs of dystrophy. As far as MRI is concerned, no specific sign of mammary neoplasia seems to exist. A classification is suggested, taking into account morphology and parameters of relaxation.

Adenofibroma↗