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Biomedical subjects

J L Jost

Publications and source records attributed to J L Jost.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Adrenal-posterior pituitary imbalance in digestive cancer patients].

In a group of 10 patients with a cancer of the digestive tract, some investigations, performed before the surgical intervention, showed the evidence of an adrenal-postpituitary imbalance in favour of the second term. During a water loading, the plasmatic cortisol rates stayed more higher by cancerous subjects than by controls (but not the plasmatic aldosterone rates); nevertheless, the vasopressin secretion rates could be considered as more higher yet in cancerous subjects because the free water clearances were significantly lowered by these patients. Such results have to be put in relation with the opposite effects of vasopressin and corticoids on the cell mitosis, as well as with some therapeutical attempts that end to check this type of endocrine imbalance.

Adenocarcinoma↗
PubMed1986

[New data on the adrenal-post-pituitary system of cancer patients].

A water loading test was performed in 10 patients with a cancer of the digestive tract without hyponatremia and in 10 controls. A lowering of the CfH2O was observed in the patients during the test, as well as an increase in the cortisol plasmatic rates, while aldosterone rates remained normal. To valid the hypothesis of a hypervasopressinic state in these patients, 15 cancerous patients and 12 controls had a plasmatic ADH dosage, which pointed indicated higher hormonal level in the first group.

Aldosterone↗
PubMed1986

[Enteropathy caused by clofazimine].

A case of Clofazimine enteropathy is reported, diagnosed on the demonstration of red brown birefringent crystals in the small bowel mucosa and submucosa as well as in the mesenteric lymph nodes whereas the clinical and radiological signs appear to be non specific. After the withdrawal of the drug, a clear improvement of the symptoms was achieved only under a gluten free diet. The possibility of such accidents, sometimes lethal, suggests the restriction of clofazimine to leprosy.

Clofazimine↗
PubMed1985

[Hemorrhoidectomy by surgical excision with anoplasty by mucocutaneous suture].

The technique suggested here consists of radical excision of the haemorrhoids with preservation of skin flaps which are sutured to the healthy rectal mucosa inside the anus. There is no traction nor sphincteral damage. This simple procedure, derived from the Whitehead's technique, is suitable for large haemorrhoids, notably when they are prolapsed and associated with lesions of the mucosa Resections "as required", with preservation of healthy mucocutaneous bridges, avoids the development of stenosis. Rectal palpation by the patients themselves twice a day from the 8th to the 30th post-operative days is essential. In a series of 150 cases evaluated 5 to 15 years after surgery, 9 out of 10 patients showed evidence of persistent success without functional sequelae.

Anal Canal↗
PubMed1985

[Cystadenoma and cystadenocarcinoma of the pancreas. Apropos of 7 new cases].

Cystadenomas and cystadenocarcinomas of the pancreas are tumours which remain poorly known because of their relative rarity. They are seen essentially in women aged between 40 and 60 and involve the left half of the pancreas more often than the right. The symptomatology remains latent for a fairly long time, which explains the fact that they are most often discovered only at the stage of a palpable tumour. Recent methods of investigation--echotomography and computed tomography--are of very great value in preoperative diagnosis. It is extremely important to draw the distinction within the group of benign cystadenomas between microcystic forms and macrocystic forms or mucinous cystadenomas, the latter having a definite potential for malignant change, possibly explaining the link with certain cystadenocarcinomas. As a result, excision surgery is always preferable, when possible, to bypass surgery, at least in caudal or corporeo-caudal lesions, since excision surgery is usually easy. For cephalic lesions, if excision surgery seems difficult, it may be conceivable, using modern techniques of investigation, to adopt a conservative attitude when there are no features suggestive of potential malignant change.

Adult↗
PubMed1981

[Radiomanometric studies of bile flow during surgery on extrahepatic biliary ducts: effects on postoperative course in 1600 patients after follow-up for more than 5 years (author's transl)].

The use of a simple, rapid, and reliable method for studying the anatomy and physiopathology of the main biliary pathway during operation by means of radiomanometry is described. This procedure enables a rational and precise therapeutic decision to be taken, as shown by comparing the results obtained in 1600 cases after a period of 5 years, with the interpretation of the initial radiomanometric findings and the type of operation performed. The overall rate of error based on the radiomanometric results, and leading to erroneous therapy, was 2 p. cent (0.43 p. cent excessive and 1.57 p. cent insufficient). No complications due to the method were observed. The main points noted were the absence of wounds to the main biliary pathway and of external bile tract fistulae, and a considerable reduction in the number of repeat operations and postcholecystectomy syndromes (1.5 p. cent).

Bile Ducts↗
PubMed1981

[Reflections concerning the fixation of the small intestine or of mesentery in the adult (author's transl)].

On the basis of their own observations as well as those collected during a round table meeting of the Association Française de Chirurgie, the authors attempt to give an objective review of the value of these operations in relations to the technique used, the operative circumstances and the indications. A detailed analytical study shows that mortality and morbidity have a relatively low prevalence. Long term results are favourable in 73% of cases. The risk of recurrent obstruction is of 5 to 10%. Emphasising contraindications on a so-called "prophylactic basis" and in certain pathological states, the authors conclude that such procedures are valuable in recurrent obstructions and deperitonisations after extensive viscerolysis.

Humans↗