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Biomedical subjects

J L Herzberg

Publications and source records attributed to J L Herzberg.

5 recordsLinked to original sources

The aetiology of aggression in temporal-lobe epilepsy.

A retrospective case-note survey was carried out on 31 subjects admitted with temporal-lobe epilepsy to the Maudsley hospital from 1974-1983 inclusive. Fourteen aggressive subjects were compared with the non-aggressive patients on 95 organic, developmental, and social variables. Aggressive behaviour was associated with male sex, early onset of seizures, and a history of long-standing behavioural problems. Aggressive subjects had lower mean IQ scores and poorer occupational records than controls. No relationship was found between aggression and the presence of specific EEG or CAT scan findings, or a history of psychosis. The results demonstrate the complex interplay between organic and socially mediated factors underlying aggressive behaviour in temporal-lobe epilepsy.

Adolescent↗

No fixed abode. A comparison of men and women admitted to an East London psychiatric hospital.

There is little information available on psychiatric disorder in homeless women. This study compares clinical casenote information of all homeless women admitted to an East London psychiatric hospital from 1971-1980 inclusive, with information on a cohort of homeless men admitted during the same period. The results show that the women appear to have been socially more stable than the men prior to admission and yet they have less satisfactory admissions to hospital. Possible reasons for these apparent inconsistencies are discussed.

Adult↗

No fixed abode.

The mentally ill homeless tend to fall into three broad diagnostic groups: the functionally ill who suffer predominantly from schizophrenia, alcoholics, and the personality disordered. Mentally ill patients may avoid medical services completely and if hospitalized are often discharged to inadequate accommodation and unsuitable aftercare. There is evidence that small numbers of both chronic alcoholics and those with personality disorders can benefit from care given by highly trained workers in small community-based units. The problems of all destitute people are worsened by a lack of accommodation for the single poor.

Adult↗

Has sodium valproate hypnotic effects?

Eight fasting normal subjects were given a single dose of sodium valproate, 400 mg, phenobarbital, 60 mg, or the two drugs in combination, in a double-blind placebo-controlled study. The effects were assessed behaviorally and by a standard 30-min EEG, begun 1 hr after the treatments had been given. The recording was rated for the amount of drowsiness and sleep, independent of which drug had been given. The scores obtained indicated that valproate intself has hypnotic action, and there is a tendency for this to be increased by the simultaneous administration of phenobarbital.

Adult↗