[The consultant's activity in hospitals. The work of a specialist in chest surgery outside the special department].
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Biomedical subjects
Publications and source records attributed to J L Hansen.
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Pneumothorax, persisting in spite of efficient drainage, may in some cases be caused by discrepancy between lung volume and size of the pleural cavity. The logical treatment is reduction of the pleural cavity simultaneously with a traditional surgical procedure on the pulmonary tissue. An increasing number of refractory pneumothoraces--both spontaneous and istrogenic--is probably due to the fact that more people are living with and suffer the sequelae of pulmonary disease. During a 15-year survey a parietal pleurolysis, tailored to fit the size and shape of the lung, was performed in 10 patients as the main surgical procedure in 100 thoracotomies for 1130 cases of spontaneous and 62 cases of iatrogenic pneumothorax. The results were encouraging.
On suspicion of tumour, thoracotomy was performed in 91 patients, who proved to have pulmonary tuberculosis. Short-term antituberculous chemotherapy was given pre-operatively in 66 cases. The 89 surviving patients received antituberculous chemotherapy after operation, and were examined one year after its termination. No signs of dissemination or other tuberculous manifestations were found, whether pre-operative therapy had been given or not.
Thoracotomy was performed in 91 patients who proved to have pulmonary tuberculosis. A short course of antituberculous chemotherapy was given preoperatively in 66 cases. The surviving 89 patients received antituberculous chemotherapy postoperatively, and were-re-examined from 1 to 14 years after the operation. No signs of dissemination or other tuberculous manifestations were found 1 year after termination of chemotherapy, even if preoperative treatment had not been given. One recurrence was seen 7 years after operation despite 9 months postoperative antituberculous chemotherapy. This was the only tuberculous manifestation. The survival rate was normal in the first 3 years compared with a corresponding Danish population, but became slightly reduced 10 years after operation. The quality of life did not seem to be significantly changed as estimated by the degree of disablement which could be correlated to the operation.
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We compared two methods for serum thyroxine measurement by competitive protein binding - the Murphy and Pattee and the Seligson and Seligson methods. We found the Seligson and Seligson method, which requires less sample volume and analysis time, to be the method of choice on the basis of sensitivity, extraction efficiency, precision, and accuracy. Standard plots of time/10,000 counts versus thyroxine concentration are linear to 20 ug/dl, extraction efficiency is 99.6 per cent, within-day S.D. plus or minus 0.28 ug/dl, and 98.3 per cent of added thyroxine is recovered in the Seligson and Seligson method. The Seligson and Seligson method is superior to the Murphy and Pattee method with respect to all these parameters. The methods were also compared with correlation and normal value studies.
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