Biomedical subjects

J L Gladstone

Publications and source records attributed to J L Gladstone.

12 recordsLinked to original sources

PubMed1981

Rubella exposure in an obstetric clinic.

Despite a massive national rubella immunization program, rubella infection remains a public health problem. When a nurse employed in a hospital-based obstetric clinic became ill with rubella, a crisis was precipitated. The hospital staff implemented a plan to inform the exposed 151 patients and 44 employees of the potential danger to themselves and their fetuses. To identify persons at risk, a program of rubella antibody testing of contacts was instituted. In 3 distinct attempts to obtain blood specimens, patient compliance rates fell progressively from 79 to 14%. One additional infected employee was detected. A list of recommendations designed to prevent or lessen the impact of future rubella exposures in hospitals is presented.

Adolescent↗

PubMed1979

Antibiotic control in a municipal hospital.

The choice of an antibiotic for a patient is often a difficult decision. The clinician must contend with a bewildering variety of bacteria and use a number of expensive and toxic antimicrobial agents judiciously. To deal with the problems of excessive and inappropriate use, the medical staff of Coney Island Hospital established compulsory, prospective antibiotic control. Two years after initiation of this program, we analyzed changes in sensitivity patterns of hospital flora, physicians' prescribing habits and antibiotic use. A trend toward increasing resistance on the part of some Gram-negative isolates to certain beta-lactam antibiotics was noted. Antibiotic costs decreased an average of 38%, while prescribing skills improved.

Anti-Bacterial Agents↗

PubMed1976

Host factors and infectious diseases in the elderly.

Because of declining function of their immunologic and other organ systems, elderly individuals are more susceptible to certain types of infections of their heart valves, meninges, urinary tract, and skin. They may develop serious sepsis with subtle clinical signs and symptoms, which makes accurate diagnosis difficult. The antimicrobial agents of choice for use against the organisms most commonly responsible for these septic symdromes are listed in Tables 2, 3, and 4. Some methods of preventing these infections are discussed, but further studies to verify old techniques and establish new ones are needed.

Adolescent↗

PubMed1976

Treatment of Candida endocarditis and arteritis.

A patient suffering from Candida endocarditis presented with a gangrenous foot. In addition to arterial embolism, occult mycotic aneurysms were found by arteriography. Clinical cure was achieved with a combination of chemotherapy and valvular débridement, but viable Candida persisted in an easily removable embolus. Occult peripheral vascular lesions may be a continuing source of Candida sepsis in some patients.

Adult↗

PubMed1971