Intramolecular cross-linking of single-stranded copolymers of 4-thiouridine and cytidine.
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Binding Sites↗
Biomedical subjects
J L Fourrey
Publications and source records attributed to J L Fourrey.
Synthesis, chemistry, and biological activity of 5-thiocyanatopyrimidine nucleosides as potential masked thiols.
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Animals↗
Alkali sensitikvity of 3-methylpyrimidine nucleosides.
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Alkalies↗
Synthesis and photochemical behaviour of a T-T dimer containing an amide linkage.
A T-T dimer characterized by an amide linkage to replace the phosphodiester backbone has been synthesized using a modified radical strategy. The new synthetic approach makes use of a thymidin-3'-yl phosphorodithioate derivative as a precursor of 3'-allyl-3'-deoxythymidine. Standard chemical transformations of this derivative led to the desired T-T dimer incorporating an amide bond. The latter was irradiated with 254 nm wavelength light to yield mainly cyclobutane and [6-4] photoadducts.
Amides↗