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Biomedical subjects

J L Ferran

Publications and source records attributed to J L Ferran.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Ultrasonography of an aneurysm of the great vein of Galien (author's transl)].

In a 15 day-old infant who presented with heart failure on the 4th day of life, the discovery of a continuous murmur at the level of the cranium led to suspicion of an aneurysm of the vein of Galien. Chest and neck profile X-rays showed an enlargement of the great vessels at the base of the heart and a thickening of the retropharyngeal soft tissues. Cerebral echotomography through the fontanelle showed an anechoic round area located in the posterior part of thalamus. Cerebral angiography confirmed the diagnosis.

Angiography↗
PubMed1981

[Ultrasonography before surgical operation of retroperitoneal malignant tumors in childhood (author's transl)].

Abdominal tumors in childhood are diagnosed almost always by palpation only, the retroperitoneal localization of these are confirmed by I.V.P. The new gray scale ultrasound machine seem to be very useful in the staging of the masses before the surgical operation. For the correct appreciation of the sensibility of gray-scale ultrasound, 6 Wilm's tumors, 6 neuroblastoma and 1 malignant retroperitoneal fibroma were reviewed. These children were echographied just before the surgical procedure and the surgeon's reports were compared with ultrasonics findings. If the sensibility is good to give measurement of the masse and to establish the situation of the tumor toward the midline of the abdominal cavity, the visualisation of the great vessels was not so obvious. However these hepatic structures were well established in all cases. The renal vein was never seen. At the end of this report it's possible to describe differential echographic findings between Wilm's tumor and neuroblastoma. --A Wilm's tumor is a mass well limited in periphery, confused with the kidney and with a frequent sonolucent rim sign. --A Neuroblastoma is a very irregular tumor well separated of the kidney without sonolucent area in its limit. U.S. made after an I.V.P. is in all cases very useful to surgeons. The two methods with their additional findings make almost always arteriography without interest.

Adolescent↗
PubMed1981

[Splenic abscess caused by Ristella fragilis : a case report of a 2 years-old boy (author's transl)].

This is a case report concerning a 2 years-old white boy who suffered sepsis fever with isolation in blood culture of an anaerobic bacteria (Ristella or Bacterioïdes fragilis). Despite continued specific therapy with clindamycine, a mass rapidly developed in the upper left portion of the abdomen which was investigated by plain film, barium enema, upper G.I. series and ultrasound study. The diagnosis of splenic abscess was only made at laparotomy. Splenectomy was a difficult procedure and needed an extension to the chest because of diaphragmatic adhesions. Culture of pus from the excised spleen grew bacteroides fragilis also, and metronidazole was added for therapy. Recover was uneventful with a 3 years follow-up. The authors emphasized the difficulty of clinical diagnosis of splenic abscess, the difficulty of bacteriological study of anaerobic bacteria and the scarceness of such cases, especially in pediatric literature. They ask the question about the legitimacy of splenectomy.

Abscess↗
PubMed1980

[Pyloric duplication with pancreatic heterotopia (author's transl)].

This is a case report concerning an 11 month old young boy with a pyloric duplication resulting in an acute gastric outlet obstruction. Pyloric duplications are rare anomalies of the gastro intestinal tract, usually cystic and few have been reported with pancreatic heterotopia and cytosteatonecrosis. Pathogenesis is quite uncertain. Most of them are discovered in the first year of life, mimicking an hypertrophic pyloric stenosis or resulting in an emergency like our case. The treatment is surgical and must choose between radical excision with sometimes partial gastrectomy or antro-pylorectomy, and incomplete resection because of its benign condition.

Choristoma↗
PubMed1979

[Juvenile polyposis. A report on two cases (author's transl)].

The discovery of multiple polypi in a small child does not necessarily indicate that this is a case of familial adenomatosis. Two cases of juvenile polyposis were confirmed by histological examinations, and their clinical and, more particularly, their radiological characteristics were studied. The only way to explore the full extent of the lesions in a satisfactory manner is by double-contrast examination of the whole colon. The authors stress the value of radiological examinations, though the frequency with which they should be carried out is open to discussion. Review of the published literature reveals that the association of true familial polyposis or adenocarcinomatosis exists in the same family or even in the same patient. Diagnostic difficulties are usually due to the fortuitons co-existence of a lymphoid hyperplasia, the significance of which is still not known.

Adenocarcinoma↗
PubMed1979

[Bronchial atresia of a segment (author's transl)].

Bronchial atresia of a segment in the lung is a very uncommon cause of pulmonary disorder. The diagnosis is very easy. The plain film is sufficient. Distension of a segment with air trapping during the inspiratory phase with one or more tumor in the hile due to the impaction of mucous secretion of the bronchi above the obstruction. Frequently asymptomatic the revelation is accidental during the evolution of a communal upper respiratory tract infection. The treatment is surgical.

Bronchi↗
PubMed1979

[Eosinophilic gastroenteritis in 2 child].

A boy aged 12 years is described who had eosinophilic gastroenteritis, a rare condition in childhood and one that is difficult to diagnose. Eosinophilia in the peripheral blood is a useful diagnostic clue. Although the histological appearances suggest an allergic process, the aetiology is unknown.

Child↗
PubMed1979

[Discitis in small children (author's transl)].

Discitis was diagnosed in 5 children under 3 years of age, the initial clinical manifestations being difficulty in walking and abdominal pains in one case. Diagnosis was not made before periods varying from 8 days to 3 months, and no etiological basis for the disease was discovered. Pinching of the disc was always present in the first radiographic image, and the vertebral plate was ill-defined in 3 cases. Repeat radiological examinations were carried out in 3 children after 6 months, 2 and 5 years respectively. There was partial restauration of the disc space in 2 cases; the last one presented signs of late collapse after early recuperation. Early perilesional bone sclerosis was noted in 2 cases, while it was posterior and late in one child. There were no sequelae (fusion, vertebra plana, scoliosis). Two investigations are essential if a disc lesion is suspected: -- radiography of the spinal column, even if there are no disturbances in walking or abdominal pains. -- scintigraphy with technitium 99, which is the only means of establishing an early diagnosis.

Child, Preschool↗
PubMed1978

[Acceleration of bone maturation in the newborn with facial dysmorphia: Marshall-Smith's syndrome (author's transl)].

The authors describe a case of Marshall-Smith's syndrome in which there was a facial dysmorphic syndrome and considerable acceleration of bone maturation (24 months to 15 days). The infant had chronic respiratory distress and the aetiology of this condition is discussed, one possibility being a pneumopathy from repeated deglutition provoked by the micro-retrognathism. Hormonal investigations were normal. Contrary to the data in the first published reports, there was a pathological increase in size, as noted in subsequent observations by Weaver. Differential diagnosis is discussed in relation to patients with non-endocrine constitutional bony diseases. The cause of this syndrome is unknown.

Bone Diseases, Developmental↗