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Biomedical subjects

J L Doyle

Publications and source records attributed to J L Doyle.

At least 37 records · Page 2Linked to original sources
PubMed1990

Multiple origins of polyploids in the Glycine tabacina complex inferred from chloroplast DNA polymorphism.

The Glycine tabacina polyploid complex has been shown to include a minimum of two morphological and crossing groups, which also differ in chloroplast DNA (cpDNA) restriction map and nuclear ribosomal gene repeat phenotype. These AAB2B2 and BBB2B2 G. tabacina polyploids contain plastomes referable to the A and B diploid plastome groups of subgenus Glycine, respectively. Eight different cpDNA variants were observed among the 65 B-type polyploids studied, six of which were identical for numerous restriction site characters to plastome types found among the highly polymorphic B genome diploid species. It is hypothesized that there have been numerous independent origins of polyploid G. tabacina: at least one AA x B2B2 event and a minimum of five BB x B2B2 events involving different BB types as female progenitor. Low amounts of cpDNA divergence between diploid and polyploid plastomes and among the plastomes of geographically disjunct polyploids suggest that the origin and dispersal of polyploids are relatively recent events. All hypothesized diploid progenitors are native to Australia, while both A- and B-type G. tabacina polyploids occur on islands of the Pacific outside the range of diploids. The presence of several different plastome types of polyploid G. tabacina in the Pacific islands suggests that several colonization events have occurred.

Journal Article↗
PubMed1989

Eosinophilic ulcer.

A 10-year review of biopsy accessions revealed 15 cases of eosinophilic ulcer. Six manifested recurrent or multiple lesions, and two exhibited histologic atypia. The possible relationships to other oral and systemic diseases are discussed.

Adult↗
PubMed1987

Odontogenic ghost cell carcinoma.

An unusual malignant odontogenic tumor containing large numbers of ghost cells is described. A 46-year-old white man had an aggressive lesion of the right maxilla, multiple pulmonary nodules developed, and he died 1 year after initial diagnosis. Histologic features included columnar odontogenic epithelium, malignant epithelium, microcysts, masses of ghost cells with focal calcification, and small areas of "dentinoid." The relationship is explored between this tumor and calcifying odontogenic cysts, particularly the "dentinogenic ghost cell tumor" variant.

Cytoplasm↗
PubMed1983

Chronic pemphigus vulgaris of the gingiva. A case report with a 6-year follow-up.

Since the initial lesions of pemphigus vulgaris often appear in the oral cavity, dentists have a major role in the recognition and diagnosis of this condition. The patient reported here was seen with a mild gingival form of the disease and has been managed successfully for the past 6 years without systemic steroids and with minimal topical steroid therapy. For most of that period he was managed without medication. Various aspects of the disease, including diagnosis, the significance of pemphigus antibodies and therapy are reviewed to provide a better perspective on this case.

Chronic Disease↗
PubMed1981

Aggressive fibrous histiocytoma of perioral soft tissues: report of case.

A rare case of aggressive fibrous histiocytoma is presented to alert the clinician to the existence of such a lesion and its ability to develop as a perioral soft tissue tumor. The research on these lesions clearly demonstrates the lability of their biologic potential. The clinical characteristics, symptoms, and histiologic makeup are reviewed and further reinforce the conclusion that careful microscopic study and thorough longterm followup to adequate surgical treatment are currently the only effective means in the management of these tumors. Continued reports from clinicians and researchers will perhaps satisfy many questions concerning this curious and potentially destructive and lethal group of lesions.

Adult↗
PubMed1980

Visceral Kaposi's sarcoma presenting with gingival lesions.

This is the first reported case of fatal visceral Kaposi's sarcoma which presented with oral lesions and in which skin lesions were absent throughout the course of the disease. Both clinical and histologic recognition may be difficult because of the similarity of the lesions to pyogenic granuloma.

Diagnosis, Differential↗
PubMed1978

Soft tissue responses to high frequency use of experimental and commercial mouthwashes.

A recent study reported that regular use of commercial mouthwashes produced a significant incidence of oral reactions, including epithelial peeling, inflammation, ulceration and geographic tongue-like lesions. In view of the widespread use of these preparations, without apparent deleterious effects, an investigation of two commercial preparations (Scope, Listerine) and an experimental mouthwash containing cetyl pyridinium chloride was undertaken to assess the possible irritant effects on the oral soft tissue under stringent test conditions. A double blind design was used and soft tissue effects were measured over a two week period. Rinses were used full strength, 20 cc 3 times daily. Examinations were conducted by an oral pathologist at the start and conclusion of the test period, and a record was made of the occurrence of erythema, hyperemia/prominent vasculature, inflammation, petechia, keratosis, tongue coating, and ulceration. These observations did not reveal any soft tissue conditions beyond those which would be expected in the normal population.

Adolescent↗
PubMed1976

Intraoral papillary cystadenoma lymphomatosum.

The literature related to intraoral papillary cystadenoma lymphomatosum is critically reviewed and the reported cases analyzed to determine the average age, sex, and race of patients, and the site distribution of this curious lesion. Two new cases are reported. The histogenesis and differential diagnosis from cystadenocarcinoma are briefly discussed.

Adenolymphoma↗