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Biomedical subjects

J L Beguiristain

Publications and source records attributed to J L Beguiristain.

At least 19 recordsLinked to original sources
PubMed1997

Lumbosacral arthrodesis using pedicular screws and ringed rods.

Sixty-one patients who had lumbar instability and chronic low back pain or deformity from nontraumatic lumbar pathologies were studied. In all of them a posterior lumbosacral fusion with CUN (Clinic of the University of Navarre) pedicle rod fixation was used. The mean follow-up period was 36 months (range 26-46 months). The consolidation rate was evaluated according to plain and functional radiographs, and a clinical evaluation was made using an analogue pain scale. The rate of fusion was 93.5%. Neurological complications occurred in 3.3%. The incidence of screw failure was 2.3% of all the screws. No other implant failure occurred. The patients rated their clinical results as 'excellent' in 33.8% of the cases, 'good' in 42.2%, 'fair' in 16.9% and 'poor' in 6.7%. CUN instrumentation is a versatile internal fixation system that has been shown to provide satisfactory stability. Furthermore, the clinical results are comparable to those reported in studies in which the most common hardwares were used.

Adolescent↗
PubMed1995

Lumbar spine anomalies in a pycnodysostosis case.

We report a case of pycnodysostosis in which several clefts in the laminas, interarticular parts, and pedicles of the whole lumbar spine were revealed for the first time on CT. We review similar findings in the literature, and discuss their pathogenesis.

Adult↗
PubMed1995

Lumbosacral instrumentation in patients with scoliosis in cerebral palsy.

We review our experience in surgical treatment of scoliosis in cerebral palsy (CP) patients to improve the functional status of such patients. The results with two types of instrumentation are reported. The best results with fusion to the sacrum were obtained with ringed rods with sublaminar and basispinous wiring, adding distraction and compression, and pedicular screws.

Adolescent↗
PubMed1994

Lumbosacral arthrodesis with louis technique. Review of 186 cases.

A retrospective study was carried out of 186 patients surgically treated by lumbosacral arthrodesis using Louis plates from 1981 to 1989 with an average follow-up of 7.2 years (range 3-11). The average age of the patients was 42.2 years (range 11-71). The indication for surgery was a herniated disc and segmentary instability in 29% (54 patients), spondylolysis or spondylolisthesis in 26.3% (49 patients), arthrosis in 11.3% (21 patients), instability (narrowing of the disc space and zygapophyseal hypertrophy) and stenosis in 5.9% (11 patients), tumour in 5.4% (10 patients), fractures in 0.5% (1 patient) and combinations of the above in 21.5% (40 patients who mainly had a herniated disc and associated spinal stenosis). Iliac crest autograft was used in 33 cases (17.7%), bank allograft in 5 (2.6%), and in the other 148 patients the graft was obtained from the arthrodesis bed. After follow-up we observed loosening of the screws in 20 patients and screw rupture in 10. We only documented 2 cases of pseudarthrosis using dynamic X-radiography. We conclude that the Louis plate is a simple method that leads to lumbosacral arthrodesis with a low rate of pseudoarthrosis.

Adolescent↗
PubMed1993

Eosinophilic granuloma of the spine with and without vertebra plana: long-term follow-up of six cases.

Vertebral eosinophilic granuloma is a rare condition frequently associated with vertebra plana. In this paper we present six patients with eosinophilic granuloma of the spine; three were without vertebra plana, which represents a diagnostic problem. The mean follow-up was 9 years, (range 2 to 23) and the mean age was 10.8 years at diagnosis. All complained of pain with no neurological deficit. The lesions were located on the vertebral bodies of C4, T9, T10, L1, L2, and L5, respectively. Histologic confirmation of diagnosis was obtained in all patients, two by puncture and four by open biopsy. The patients with vertebra plana (T10, L1, and L5, respectively) were treated conservatively. Long-term follow-up demonstrated total healing of the vertebral body in two and partial rebuilding 8 years after diagnosis in one. Patients without vertebra plana (C4, T9, and L2, respectively) underwent curettage and bone grafting. In the patient with T9 location, a T8-10 anterior arthrodesis with autogenous rib graft was performed. The outcome was satisfactory in all.

Adult↗
PubMed1992

Neurologic complications after sublaminar wiring. An experimental study in lambs.

To study possible neurologic complications, five lambs were operated on by sublaminar wiring at the thoracolumbar spine. Monitoring of the central motor pathway was carried out by percutaneous electrostimulation. A comparative anatomic study was designed to compare the magnitude of the spinal canal and the area occupied by the spinal cord at the low thoracic and lumbar level in 15 lamb, 8 pig, and 8 human spines. The following parameters were measured by slide caliper: the anteroposterior diameter of the spinal canal and the spinal cord, the length and thickness of the laminas, and the distance between each consecutive lamina. All five operated lambs showed major neurologic deficits after surgery. The results of the anatomic study suggest that there exists in humans a sufficiently ample "safety zone" that permits wire insertion without risking injury to neurologic structures. Such a "safety zone" is nonexistent in lambs and pigs unless an extensive laminectomy is performed to decrease the depth of wire penetration.

Animals↗
PubMed1989

The neurocentral vertebral cartilage: anatomy, physiology and physiopathology.

The neurocentral cartilage (NCC) described by Schmorl was an intermediate cartilage has aroused discussion among numerous authors as to its role, its age of closure and its possible involvment in the genesis of scoliosis. The authors have attempted to define these problems on the basis of a histologic study of 20 vertebral specimens of different ages and a scanographic study of 25 children. The NCC remains open until adolescence and even beyond, but its maximal activity is probably around 5-6 years. Part of its function is to ensure growth of the posterior arch. Finally, the scanograms of scoliosis show the NCC to be more widely open on the concave side, as if this remained active for a longer period.

Adolescent↗
PubMed1987

Scoliosis induced by medullary damage: an experimental study in rabbits.

To date, there have been no reports of experiments designed to induce scoliosis by direct damage of different areas of the spinal cord. In a series of rabbits with medullary damage, the authors attempted selectively to interrupt the pathways that mediate proprioceptive input. Unilateral lesion of the dorsal column and posterior horn of the spinal cord was performed using three different techniques: coagulation with laser, stereotaxic microcoagulation, and longitudinal electrocoagulation. Of 32 operated rabbits, 17 developed scoliosis, exhibiting clear pathologic damage of the spinal cord. Electrophysiologic study, including EMG and analysis of the tonic -- vibratory reflex, was performed on 10 rabbits with medullary damage (scoliotic and non-scoliotic) and 12 matched controls. The data suggest disturbance of the sensory afferences that control the postural tone and consequent muscular imbalance, expressed as reduced activity in the muscles of the convex side. This work supports the view that loss of proprioceptive neural impulses caused by medullary damage can induce scoliosis.

Animals↗
PubMed1986

Discitis due to Clostridium perfringens.

Diagnosis of the infectious process of the intervertebral disc is often delayed due to the lack of specifity of the clinical picture. This delay in diagnosis and consequently in treatment can lead to severe neurologic sequela. In these cases, punction biopsy of the intervertebral disc is of special value. The authors found no mention in the literature concerning Chlostridium perfringens discitis verified by aspiration and fluid culture extracted by intervertebral disc puncture.

Adult↗
PubMed1983

Surgical treatment of metatarsalgia. Long-term evaluation of 105 cases.

The authors present a long-term evaluation of a special treatment of metatarsalgia. The results are based on clinical findings, footprints and radiographs. The postoperative results provide a satisfactory evaluation of our technique and understanding of the biomechanics in the foot.

Adult↗
PubMed1980

The production of experimental scoliosis by selective arterial ablation.

Through a lateral thoracotomy, microcoagulation of the proximal segment of the intercostal artery and of its principal posterior collateral was carried out at four consecutive levels in rabbits. Subsequently, structural scoliosis developed in 67.5% of animals. Histological examination of the spinal cord in all animals showed that characteristic changes were found in the animals with scoliosis. It is suggested that these changes were ischaemic in origin and caused abnormal neuromuscular responses in the paravertebral muscles, resulting in scoliosis.

Animals↗
PubMed1980

Experimental scoliosis by epiphysiodesis in pigs.

Using two-month-old pigs selective epiphysiodesis of the neurocentral cartilage was performed using cancellous screws inserted to achieve effective compression. The operation was performed on eight experimental animals, on the right side, involving four or five vertebrae at the mid thoracic level. The procedure consistently caused structural scoliosis, convex on the side of operation. The radiographic, macroscopic and microscopic findings in the experimental animals are described. In other animals so treated at ages when the neurocentral cartilage is not active rotational deformity did not occur.

Animals↗
PubMedDate not supplied

[Surgical treatment of vertebral metastasis].

Spinal metastases may cause pain and neurologic dysfunction secondary to bone destruction and spinal cord compression. The new oncology therapy have prolonged life expectancy of many patients with different primary tumors. The treatment of metastases is frequently necessary to enhance quality of life. We reviewed 121 patients with spinal metastases of different primary tumors operated between 1982 and 1995. We employed different approach and instrumentation depending on particular case, metastases location and life expectancy. We analysed primary tumor location, spinal pain, neurologic function, pre and post surgical treatment, complications and development. Spinal stabilization and cord decompression gives excellent results for pain relief, neurological improvement and quality of life, always helping to medical treatment of a patient with metastatic disease.

Adolescent↗