Biomedical subjects

J Kwiatkowski

Publications and source records attributed to J Kwiatkowski.

At least 37 records · Page 2Linked to original sources

PubMed1985

Continuous speech sampling for phonologic analyses of speech-delayed children.

Five conditions for sampling the continuous speech of speech-delayed children were defined and compared. Conditions differed on variables associated with examiner behavior and stimulus materials. All sampling conditions were administered in randomized order by two examiners who each tested 6 children. The obtained speech samples were compared for productivity, intelligibility, representativeness, and reactivity. The general findings of few significant differences associated with sampling conditions support the validity of continuous speech sampling for phonologic analyses of speech-delayed children. Protocols for the five conditions are provided, and guidelines for efficient speech sampling are suggested.

Child, Preschool↗

PubMed1984

A procedure for phonetic transcription by consensus.

A consensus transcription procedure is presented, and representative data are reported. The procedure includes explicit response definitions for mapping narrow phonetic transcription onto dichotomous, nonerror/error scores and 17 rules for obtaining consensus between two transcribers. The data include descriptive statistics for consensus rule use based on over 18,000 sounds transcribed during a normative study of speech sound acquisition in children aged 3-6 years. Validity and reliability issues in phonetic transcription are discussed.

Child↗

PubMed1982

Phonological disorders I: a diagnostic classification system.

Data are presented to support the validity and utility of a diagnostic classification system for persons with phonological disorders. Rationale for the classification system is developed from current reviews of issues and concepts in phonology and classification systems. The system proceeds from a worksheet for reduction of phonological and other assessment data, through five hierarchical levels of classification entries. The system will accommodate lower-level elaboration of etiological subgrouping, pending appropriate research. A retrospective classification study of 43 children with delayed speech is described. Procedural details relating classification procedures to two companion papers (Shriberg & Kwiatkowski, 1982a, 1982b) are provided.

Adolescent↗

PubMed1982

Phonological disorders II: a conceptual framework for management.

A conceptual framework for management of phonological disorders is proposed. The framework includes a 10-element system for describing the structure of management programs and invokes a diagnostic classification system for determining appropriate management content. Data from three serial studies of management structure describe the effectiveness, efficiency, and clinician acceptance of four modes of management: Drill, Drill Play, Structured Play and Play. Review of past, present, and future content of management programs emphasizes the central role of individual differences among persons with phonological disorders.

Child↗

PubMed1982

Phonological disorders III: a procedure for assessing severity of involvement.

Data are presented to support the reliability, validity, and utility of a severity metric for phonological disorders. The metric, percentage of consonants correct (PCC), is readily derived from a continuous speech sample. PCC values are shown to reflect an ordinal severity scale that embraces the constructs of disability, intelligibility, and handicap. PCC values index four levels of "severity of involvement": Mild, mild-moderate, moderate-severe, and severe. The metric provides a means by which instructors, researchers, and speech-language pathologists working in different settings can specify subject descriptions, gauge the effects of intervention programs, and undertake cross-institutional projects. The metric is used as one component of a diagnostic classification system for phonological disorders (Shriberg & Kwiatkowski, 1982a) and within a framework for management of persons with phonological disorders (Shriberg & Kwiatkowski, 1982b), the first and second papers in this series.

Child↗

PubMed1980

Changes in blood flow and permeability of vessels to protein preceding the development of cutaneous ulcers in the hind limb of the rabbit.

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Animals↗

PubMed1980

[Morphological changes in the bypass transplant of autologous reversed vein in patients with femoral arteriosclerosis].

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Arteriosclerosis↗

PubMed1979

Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast.

Activities of some enzymes associated with carbohydrate and lipid metabolism were determined in 48 human breast carcinomas and compared with those found in 35 nonmalignant breast tumours and also in 13 normal breast tissues. In fibrocystic disease only the activity of citrate lyase was markedly higher (14-fold) than in normal tissue. The activities of the remaining enzymes did not differ significantly from those in normal tissue. Enzyme activities in breast carcinoma were 4--160 x those determined in normal tissue according to the following sequence : phosphofructokinase less than malate NADP dehydrogenase less than hexokinase less than lactate dehydrogenase less than isocitrate NADP dehydrogenase less than ATP citrate lyase. Activity of citrate lyase, very low in normal breast (0.0017 mumol/min/g of tissue) rose gradually to 0.039, 0.072 and 0.258 mumol/min/g of tissue in localized fibrocystic disease, fibroadenomas and carcinomas respectively. These data support the idea that citrate lyase may play an important role in lipogenesis in hyperplastic human breast tissues.

Breast↗

PubMed1977