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Biomedical subjects

J Kumate

Publications and source records attributed to J Kumate.

At least 109 records · Page 6Linked to original sources

[Optimal age for vaccination against measles].

A review of the general aspects of the transmission dynamics of measles is presented. Similarities and differences in the patterns of transmission of measles in developed and developing countries are pointed out. Epidemiological, demographic and nutritional variables relevant to the design of an immunization program are briefly discussed. Since there is no cohort in developing countries in which most individuals are susceptible, it is concluded that there is no single optimum age at which to vaccinate against measles. Finally, a simple method based upon case notification records, for calculating the force and average age of infection as well as the optimum age for vaccination against measles is illustrated.

Adolescent↗

[Primary health care as an instrument of development in Mexico].

A Primary Health Care (PHC) score is obtained by averaging thirteen indicators of PHC of each state of Mexico with data of 1985. Some correlations between the PHC score with other indicators of development, such as education and urbanism, are analyzed. The socioeconomic and educational status of women impinge directly in the processes of PHC. Based upon results of basic research some features of coverage and selectivity of PHC strategies are analyzed.

Developing Countries↗

[Induction of protective antiamebic immunity in hamsters with heterologous antigens].

Two hundred and twenty-five Syrian golden hamsters were used. Twenty five of them served as the control group. All other hamsters were intradermal immunized, once a week for four weeks, with a mixture of amebic proteins, mixed with complete Freund adjuvant, obtained from 5 x 10(5) homogenized dead amebic trophozoites from five different strains. Each group of hamsters (five groups of 40 animals each) were immunized with one of the following strains: E. histolytica HM-531, HJ-1, HM1-IMSS, E. chattoni PM-4 and PM-5. All hamsters, including those from the control group, were later inoculated with 0.2 mL equivalent to 1 x 10(5) live trophozoites from the different strains grown in axenic TYI-S-33 medium. Inoculation was performed by direct injection into the liver. The hamsters were sacrificed eight days later and their livers examined. All non-immunized animals showed extensive gross hepatic nodular abscesses. The liver of immunized hamsters showed mild to moderate lesions: the histopathological striking feature was non-specific granulomata. It is concluded that the immunized animals inoculated with homologous stock showed protective immunity to amebic infections. In other cases, immunity was seen though they were inoculated with a heterologous stock.

Animals↗