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Biomedical subjects

J Kronenberg

Publications and source records attributed to J Kronenberg.

14 recordsLinked to original sources

[Cochlear implantation].

Since the Israeli cochlear implant program was started in June 1989, 74 candidates have been evaluated for implantation. The main causes for hearing loss were meningitis (16 patients), aminoglycoside toxicity (9), congenital (6), viral (e.g. mumps) (6), and middle ear infection. Candidates were rejected mainly due to psychosocial factors (40%) and audiological parameters (30%). 16 postlingual deaf were implanted. In 7 of them (43.7%) the results were excellent, in 4 (25.0%) good, in 3 (18.7%) fair; 1 case is currently in a training program and 1 is a failure. There were 2 major complications: facial nerve palsy which necessitated surgical decompression, and insertion of the electrodes into the hypotympanic air cells, corrected by reoperation.

Cochlear Implants

Nasal ciliary motility in retinitis pigmentosa.

Normal in-vitro ciliary beat frequency is reported in a patient with retinitis pigmentosa. The significance of electromicroscopic ciliary defects in this condition is appraised.

Ciliary Motility Disorders

Vasoactive therapy versus placebo in the treatment of sudden hearing loss: a double-blind clinical study.

Twenty-seven patients suffering from sudden sensorineural hearing loss (SHL) were randomly assigned to one of two groups: a treatment group (n = 13) receiving intravenous procaine and low-molecular-weight dextran, and a placebo control group (n = 14). The effect of treatment was analyzed by means of an analysis of variance and covariance procedures. Results indicated nonsignificant differences between the groups on all outcome indices measured. Sex, age, time since the onset of symptoms to the initiation of therapy, audiogram configuration, and initial severity of hearing loss did not significantly affect the results. These findings suggest that the therapeutic effects of this vasodilator are not superior to a placebo.

Adult

Severe hypophosphataemia during binge eating in anorexia nervosa.

A patient presented with severe hypophosphataemia that had been precipitated during binge eating. It was corrected by restricting the binges, and by hyperalimentation through a duodenal tube together with intravenous supplementation with sodium phosphate for a short period. Phosphate concentrations should be monitored in patients with severe anorexia complicated by bulimic episodes.

Adolescent

Blast injury of the ear.

The course of middle ear injuries secondary to blast effect was evaluated in 147 soldier-patients (210 ears) during the years 1967-1986. All perforations were in the pars tensa of the tympanic membrane. Ossicular chain interruption (11 ears) was associated mainly with dislocation of the incudo-stapedial joint. Mixed-type hearing loss was most prevalent (37%). Spontaneous closure occurred in 155 ears (73.8%), most of them (65.5%) within a 3-month period. Seven ears (3.3%) developed simple chronic suppurative otitis media; in 10 (4.8%), an invasive cholesteatoma developed, and in 6 others (2.8%), epithelial pearls were encountered behind an intact eardrum. Thirty-two patients were treated by immediate patching of the perforated drum, with an 84% rate of spontaneous closure; no cholesteatoma developed among this group, emphasizing the need for immediate patching. Tympanoplasty is recommended 1 year following the injury, and a 4-year follow-up period for detection of late complications is also recommended.

Adolescent

[Decompression of the endolymphatic sac].

Preliminary results in 8 patients with Meniere's disease who underwent decompression of the endolymphatic sac in the past 3 years were good. There was improvement in general disability, and tinnitus control in 87.5% and stabilization of hearing in 62%. The single complication was dead ear in 1 patient. These results are in the acceptable range and encourage continuation of this operation.

Adult

Conservative management of adult epiglottitis.

A 10-year retrospective study of 30 adults suffering from acute epiglottitis is reported. Two clinical forms of onset were noted: gradual and accelerated. Abscess formation was present in 27% of cases. None of the patients required intubation or tracheotomy. In contrast to the accepted interventionist approach in children, conservative management in adults is recommended.

Abscess