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Biomedical subjects

J Kozak

Publications and source records attributed to J Kozak.

At least 19 recordsLinked to original sources

Video-assisted thoracoscopy for closure of a bronchial stump fistula.

It is thought that thoracoscopic closure of a bronchial stump fistula is beyond the capabilities of current thoracoscopic techniques. We describe the successful use of thoracoscopy in the therapy of a late right main bronchial stump dehiscence after pneumonectomy and chemotherapy of a stage IIIA adenocarcinoma. We clipped the fistula with a Multifire Endo Hernia Stapler (Auto Suture) and we obtained intraoperative airtight closure of the fistula.

Bronchial Fistula

The frequency of antisperm antibodies in the cervical mucus of women with poor postcoital tests and their effect on pregnancy rates.

PROBLEM: To determine the impact of the presence of antisperm antibodies (ASAs) in the cervical mucus of female partners in couples with unexplained poor postcoital tests (PCT). Furthermore, the efficacy of intrauterine insemination (IUI) in these same patients was determined by pregnancy rates (PRs). METHOD: Pregnancy rates following IUI in patients with infertility and poor postcoital tests, whether the cervical mucus was positive or negative for ASAs, were evaluated. RESULTS: The 6-month PRs were similar in the ASA negative (40.5%) versus the positive (42.4%) group. CONCLUSIONS: It appears that the antifertility effect of ASA may be mainly the immobilization of sperm in the cervical mucus, and thus, performing IUI may effectively correct the problem.

Antibodies

[Modular cemented knee prosthesis Kinemax--is manual mobilization during extended contraction justified?].

Early results of 12 total Kinemax knee replacements have been presented. Maximal active flexion has been recorded on 8th, 15th day and half a year after operation. Standard rehabilitation of the operated joint has been conducted. No manual mobilisation was employed despite of the only one case of knee flexion close to 90 degrees 2 weeks after surgery. Half a year later flexion has reached or exceeded the right angle in all cases.

Adult

Effect of swim-up, Percoll and Sephadex sperm separation methods on the hypo-osmotic swelling test.

The separation of spermatozoa from the seminal plasma is required to prepare the spermatozoa for intrauterine insemination, in-vitro fertilization and sex selection. This study evaluated the effects of sperm preparation techniques on the functional integrity of the sperm membrane, as measured by the hypo-osmotic swelling test (HOS). Thirty-four semen specimens obtained from the male partner of infertile couples were evaluated. A semen analysis and HOS test were performed on each specimen. The remainder of the specimen was divided into three equal aliquots, the first prepared using Percoll, the second using a swim-up method and the third using a Sephadex column. After the preparation, a semen analysis and HOS test was performed on each aliquot. The mean and standard deviation for the HOS test was 72.9 +/- 8.5% initially, 71.2 +/- 13.1 after Percoll, 75.2 +/- 15.1 after swim-up and 62.4 +/- 14.5 after Sephadex. Analysis of variance showed that the mean HOS score was the same after Percoll and swim-up as it was initially but significantly lower after preparation with Sephadex. There was also a higher proportion of abnormal semen specimens (HOS less than 50%) after preparation with Sephadex than after the other preparation methods. We recommend the use of the HOS test as part of a screening panel for sperm separation.

Cell Membrane

[The influence of geometry of the total hip endoprosthesis on late functional results].

The influence of some parameters of incorrect position of elements of an endoprosthesis of the hip on the late functional result of 61 endoprosthetic arthroplasties have been analyzed. The authors believe that the group of several factors of incorrect mounting of elements of an endoprosthesis is usually the cause of deterioration of treatment results due to occurrence of clinical and radiological symptoms of loosening of the endoprosthesis.

Adult

[Functional result and telemetric evaluation of gait after total endoprosthetic arthroplasty of the hip].

The late functional results of one-side endoprosthetic arthroplasty in 35 patients, supplemented with telemetric examination of temporal parameters of gait, have been presented. The marked correlation of the obtained results of telemetric examination with clinical and radiological state of the operated on hip has been found. The authors stress the favorable and rational effect of the cane in unloading of the inefficient lower extremity.

Aged

[Partial patellectomy in treatment of fresh fractures of the patella].

The late results of partial patellectomy in treatment of fracture of the apex or the 1/3 of the peripheral patella have been presented. Fourteen patients were evaluated. Attention was paid to the dependence of the result on the correct surgical technique. Full painless range of movements in the operated on knee was achieved in 7 persons. In the other 7 patients, extension of the knee was full but flexion was moderately limited. Periodical pain occurs in 3 persons.

Adult

[Resection of the patella and plasty of the knee by the de la Caffiniere method].

The surgical technique of patellectomy with preservation of continuity of the extension apparatus of the knee by the de la Caffinière method and the early results of treatment in 8 operated on patients have been presented. The indications for surgery were: posttraumatic stiffness of the knee in extension in 4 patients, patello-femoral arthrosis with preserved wide range of movement in 3 patients, fresh multi-fragmented fracture of the patella without rupture of the extension apparatus in one patient. The good treatment result was obtained in 6 patients (3 treated for patello-femoral arthrosis, 1 for fresh fracture of the patella, and 2 for stiffness of the knee in extension). The poor results in the other 2 patients operated on or stiffness of the knee in extension were due to large damage of the cartilaginous surface of the condyles and extensive intra- and periarticular adhesions.

Adult

Neuropsychological performance in psychiatric patients with or without documented brain dysfunction.

The current study examined neuropsychological performance of schizophrenic and depressed patients with and without structural or EEG signs of brain dysfunctioning. The neuropsychological test battery was designed to sample intellectual functioning, psychomotor skills, nonverbal memory, and novel problem solving ability. Patients were classified into four groups: schizophrenics without signs of brain dysfunctioning, schizophrenics with signs of brain dysfunctioning, depressed without signs of brain dysfunctioning, and depressed with signs of brain dysfunctioning. The Trail Making Test--Parts A & B, the difference between these two components of the Trail Making Test, the World Fluency Test and a Laterality Index based on the age scale scores of the WAIS significantly discriminated between patients with and without brain dysfunction. Using these variables and a Linear Discriminant Function Analysis, we found that 84.5% of our subjects could be correctly classified. Substantially fewer patients could be correctly classified with respect to their psychiatric diagnosis (i.e., 66.7% correct classification). In fact, only the PIQ from the WAIS-R showed significant differences between the depressed and schizophrenic subjects. Poor neuropsychological performance was interpreted as showing more than the behavioral disorganization associated with psychiatric states and was felt to be related to the presence of objective signs of brain dysfunctioning.

Adolescent

Impaired interns and residents.

In 1981 a study was undertaken to determine intern and resident psychological well-being and identify those house staff who were psychologically impaired. Fourteen percent of house staff were found to be impaired. Single females and house staff who were chronically fatigued or socially isolated were at highest risk for impairment. Impairment arose out of the interaction between sleep and social deprivation and individual vulnerability. Minor tranquilizers, but not alcohol, were used as a coping response to impairment.

British Columbia

Clinical utility of three measures of frontal lobe dysfunction in neuropsychiatric samples.

The utility of the Word Fluency Test, Wisconsin Card-Sorting Test, and a shorter form of the Categories Test as screening instruments for detecting frontal lobe dysfunction in a neuropsychiatric setting was examined. On the basis of clinical and neurological examination, patients were assigned to one of three groups: frontal lobe injured, brain impaired excluding the frontal areas, and psychiatric with no evidence of brain dysfunctioning. It was possible to assign correctly 66.3% of the patients to their respective groups. The Word Fluency Test made the strongest contribution to the prediction of the presence of frontal lobe pathology, even when the effects of age and postmorbid intellectual functioning were controlled. The results were consistent with the interpretation of lowered verbal fluency and deficits in the capacity to suppress habitual behaviour as a major feature of frontal lobe dysfunctioning.

Brain Damage, Chronic