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Biomedical subjects

J Kosowicz

Publications and source records attributed to J Kosowicz.

At least 55 records · Page 3Linked to original sources
PubMed1981

Elevation of maternal serum myoglobin concentrations during delivery.

Serum myoglobin was determined by radioimmunoassay in 32 women immediately after delivery, in the umbilical cord blood of 30 newborn infants, in 18 women in the third trimester of pregnancy and in 24 healthy non-pregnant women. In maternal blood following delivery there was a 3 to 10 fold rise in serum myoglobin concentration (mean +/- SD = 117.2 +/- 82.5 ng/ml). On the other hand, in umbilical cord blood and in late pregnancy, serum myoglobin concentrations did not differ from those in healthy non-pregnant women (mean +/- SD = 23.6 ng/ml).

Female↗
PubMed1980

Serum reverse triiodothyronine (3,3',5'-L-triiodothyronine) in chronic renal failure.

Serum reverse triiodothyronine (reverse T3), triiodothyronine (T3), thyroxine (T4) and thyrotropin (TSH) concentrations were determined by radioimmunoassay in end-stage chronic renal failure, hypothyroidism and control subjects. In advanced chronic renal failure serum reverse T3 was normal or elevated and serum T3 concentrations were frequently, and serum T4 occasionally, lowered. Serum TSH was normal even where serum T3 and T4 concentrations were low. Normal or elevated serum reverse T3 associated with normal serum TSH in chronic renal failure clearly differentiates this disease from primary hypothyroidism in which low serum reverse T3 and high serum TSH are constantly found.

Adult↗
PubMed1977

Abnormalities of tooth development in pituitary dwarfism.

Roentgenographic studies of the jaws and teeth in a group of forty-eight pituitary dwarfs showed the following abnormalities in the development of the teeth: 1. Delayed shedding of the deciduous teeth. 2. Absence of resorption of the roots of the deciduous teeth at the usual time. 3. Marked delay in eruption of the permanent teeth. 4. Retention of permanent teeth in the maxillary and mandibular shafts. 5. Development of the apical parts of roots of the retained permanent teeth and their growth toward the lower mandibular edge. 6. Displacement of the first molars from the mandibular shaft to rami. 7. Tilting of some of the retained teeth. 8. Small size of the maxilla and mandible with overcrowding of the teeth in these bones. 9. Complete absence of buds of the wisdom teeth, even in patients in the fourth decade of life. 10. Stimulation of development and eruption of the teeth after administration of anabolic drugs. These abnormalities when present in combination depend on growth hormone deficiency since they do not occur in other types of dwarfism.

Adolescent↗
PubMed1976

Abnormal basal angle of the skull in sex chromosome aberrations.

The basal angle was measured on skull films in 252 patients with hormonal disorders and sex chromosome aberrations. In cases of hormonal disturbance the basal angle was normal. In patients with Turner's syndrome (45,X chromosomes) the basal angle was enlarged while in patients with Klinefelter's syndrome (47,XXY chromosomes) and in those with extra X or Y chromosomes it was definitely reduced. A close relationship exists between the sex chromosome number and the size of the basal angle.

Adolescent↗
PubMed1975

Radiological features of the skull in Klinefelter's syndrome and male hypogonadism.

Skull radiographs were performed in 21 cases of Klinefelter's syndrome and in 30 cases of eunuchoidism. The radiographic changes of the skull in Klinefelter's syndrome are: temporal flattening, decreased width of the vault, narrowing of the mandible, decreased length of the skull, shortening of the anterior fossa cranii, decrease in the angle of the base, thinning of the vault bones at the major fontanelle, premature and excessive calcification of the coronal suture, deepening of the posterior fossa and shortening of the mandibular rami. In hypogonadotropic eunuchoidism the skull radiographs show: small mastoid processes, fine bones of the vault, small sella turcica, club-shaped clinoid processes, excessive development of sphenoidal sinuses and in the fourth and later decades of life a diminished bone density (osteoporosis).

Adolescent↗
PubMed1975

The skull in gonadal dysgenesis. A roentgenometric study.

Skull radiographs of 54 patients with Turner's syndrome have been studied. The following characteristic findings were frequently noted: mastoid processes of definitely decreased dimensions, small facial bones which were proportional to the stunted growth of the patients, enlargement and increased thickness of the mandible, extensive calcification of the petro-clinoid ligaments, excessive pneumatisation of the paranasal sinuses and increased angle of the base of the skull.

Adolescent↗