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Biomedical subjects

J Kolesár

Publications and source records attributed to J Kolesár.

At least 19 recordsLinked to original sources

[Changes in thermoregulation and age. Hypothermia and hyperthermia].

The author presents a review of changes in thermoregulation in various ages. The changes at infant and older ages are compared in contrast to thermoregulation in healthy adults. Hypothermia occurs in all age groups, especially in the aged. Then it is determined by both low temperature of environment and impairment in production and expenditure of heat despite the normal environment temperature. A special form of hypothermia is represented by intraoperative hypothermia in the course of surgical performance under general anaesthesia. Hyperthermia occurs most frequently as heatstroke in consequence of high environmental temperature. The author presents etiopathogenesis and pathomechanisms, possible treatment and prevention in thermoregulation disturbances. (Tab. 6, Ref. 79.).

Adolescent↗

[Hypertensive disease in the elderly and its treatment].

After presenting the epidemiologic and pathophysiologic pattern, the paper focuses on the evaluation of elderly hypertensives, on nonpharmacological and particularly on pharmacological treatment. Further, possibilities of individualized treatment, resistance to treatment, complications of hypertensive disease in elderly subjects, as well as beneficial effects of management are described.

Age Factors↗

[Combination of a carbon dioxide bath and a diuretic--follow-up study of several days].

A series of 22 men underwent a 30 minute carbon dioxide bath and was simultaneously administered Hydrochlorothiazide SPOFA. Their renal response was studied, and that both separately to the bath or the diuretic and to their combination. Diuresis was increased by 200 l x 10(-3) after the carbon dioxide bath and by 500 l x 10(-3) after hydrochlorothiazide. This increase was even further enhanced after the combination of the two treatments. Sodium excretion showed a similar increase, whereas kaliuresis did not exhibit such a marked rise and the differences between the response to the bath and to the diuretic were small. Repeated combination of the carbon dioxide bath and the diuretic resulted in a slightly increasing diuresis over the days studied. The authors emphasize the necessity to understand the bath--drug interactions particularly in balneological practice and substantiate the advantage and usefulness of the combination studied in indicated cases.

Adult↗

ECG changes and exercise tolerance in patients after myocardial infarction.

The aim of the study was to analyse the type of ECG changes in patients after acute myocardial infarction and to compare them with changes in their physical performance. The authors examined 218 patients with acute myocardial infarction after discharge from hospital. Resting ECG and step-wise graded exercise ECG test on a bicycle ergometer was carried out. The technique of examination was in accordance with WHO recommendations. Statistical evaluation was performed by the Wilcoxon-Mann-Whitney's U-test. The workload in patients showing ECG changes of "transmural" myocardial infarction was not different compared with that of persons with "non-ransmural" lesion (70.00 W versus 71.7 W). When evaluating the relation between the site of ECG changes and the workload, the authors found that the lowest tolerated workload was in cases where ECG changes suggested an extensive damage to the myocardium (53.5 W, p less than 0.05). The authors conclude that the extent of ECG changes after myocardial infarction is a better marker of the level of impairment of physical performance than patient classification to Q or non-Q types.

Electrocardiography↗

[The significance of longitudinal Holter electrocardiogram monitoring in the differential diagnosis of syncope in elderly patients].

Longitudinal monitoring of the electrocardiogram by Holter's method is indicated in particular for the diagnosis of intermittent dysrhythmia which may be related to the symptom of syncope in elderly patients. Transient dysrhythmia with subsequent cerebral ischemia may be the cause of altered consciousness, vertige, presyncopes, or true syncopes. Transient dysrhythmias may be therefore considered after elimination of other causes of syncopes as their aetiology, in particular in elderly patients and old age groups where organic heart disease is already present. In those instances Holter's ECG is a useful non-invasive examination method which makes it possible to start appropriate treatment, and later by using serial monitoring, it makes it possible to follow up the effectiveness of antiarrhytmic treatment, or to follow up the function of an implanted cardiostimulator (pacemaker).

Aged↗