Deactivation of immobilized beef liver catalase by hydrogen peroxide.
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Aluminum Silicates↗
Biomedical subjects
J Kohler
Publications and source records attributed to J Kohler.
[Surgical treatment of uncomplicated duodenal ulcer. Development of ideas and current views].
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Duodenal Ulcer↗
[Tried and newly expanded local therapy of mycoses].
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Administration, Topical↗
High-dose intravenous penicillin G does not prevent further progression in early neurological manifestation of Lyme borreliosis.
We report two cases of Lyme borreliosis (LB) with erythema migrans (EM) and simultaneous meningopolyneuritis with radicular pain and lymphocytic pleocytosis in the cerebrospinal fluid (CSF). EM and pain disappeared completely under high-dose penicillin G therapy within few a days. Pathological findings in CSF improved. Nevertheless, during and after therapy, neurological signs of LB developed: cranial nerve palsies as well as paresis of extremity muscles with radicular distribution.
Abducens Nerve↗
Listeria brainstem encephalitis: two own cases and literature review.
We analysed two of our own and 21 patients described in the literature with listeria brainstem encephalitis. The disease was characterised by a prodromal state with fever, nausea and headache followed by severe brainstem dysfunction with multiple cranial nerve palsies, ataxia, respiratory insufficiency and coma. The diagnosis was established by isolation of Listeria monocytogenes from CSF and/or serum. Serological tests are without diagnostic evidence. Cerebrospinal fluid examination may not initially point to a bacterial infection. Computed tomography and magnetic resonance imaging technique might supply evidence of brainstem involvement and contribute to an early diagnosis. There is a high percentage of lethal outcome without early antibiotic therapy.
Adult↗
Renal autotransplantation--a kidney saving procedure before spinal radiotherapy.
Renal damage is a well-known consequence of radiation therapy to adjacent tumors. We describe a child requiring spinal irradiation in whom autotransplantation of a kidney to a site outside the radiation field was performed and the renal function preserved.
Child↗
A randomized study of ondansetron syrup in children: evaluation of taste acceptability and tolerance.
Ondansetron, a highly selective 5-HT3 receptor antagonist, is available in an intravenous (IV) formulation and tables, but syrup would be particularly useful in children. As chemotherapy can affect taste perceptions, this study was undertaken to determine the preference between two flavors of ondansetron syrup in children undergoing chemotherapy. Fifty-nine children, randomized into a multicenter, double-blind, crossover study, each received 5 mg/m2 of IV ondansetron daily before chemotherapy. The syrup was then randomly given in two doses, one of each flavor, strawberry and grape, 30 minutes apart. The preference was assessed 30 minutes after the second dose of syrup had been administered. Taste was assessed by the child against a panel of five faces. Of those children expressing any preference, 70% preferred the strawberry flavor. Overall, 59% of children preferred the strawberry flavor, whilst 25% preferred grape (P = 0.005) and 15% expressed no preference. The only adverse event assessed as drug related by the investigator was constipation, which occurred in one patient. In conclusion, a strong preference was found for the strawberry formulation. The ondansetron syrup was safe and well tolerated.
Antiemetics↗