The purpose of the study was the determination of correlations between the results of electronystagmographic (ENG) investigations and the blood flow velocity in the vertebrobasilar arterial system measured by Doppler ultrasonography in patients with vertigo. The studied material comprised 68 patients (39 women and 29 men) aged 34-68 years (mean 52.4 years). ENG findings included unilateral hyporeflexia in 25 cases (37.7%), bilateral hyporeflexia in 15 (22.0%) and unilateral canal failure in 8 (11.9%). Doppler USG with neck rotation test showed normal flow velocity in 15 cases (22.0%) and pathological velocity in the remaining 53 cases (78.0%). These results showed that bilateral hyporeflexia is found usually in bilateral failure of vertebral arteries and unilateral hyporeflexia and unilateral canal failure were found with unilateral vertebral artery failure on the same side.

Adult↗

PubMedDate not supplied

Derivatives of the L-lysine-peptides with antibacterial activity.

A number of derivatives of the L-lysine peptides has been obtained and their antibacterial properties were evaluated and compared with those of the ethyl ester of Nalpha-palmitoyl-L-lysyl-L-lysine dihydrochloride. Some correlations have been found between the chemical structure and antibacterial activity of the compounds.

Anti-Bacterial Agents↗

PubMedDate not supplied

[The heart in scleroderma].

Explore the source record for details and available documents.

Cardiomyopathies↗

PubMedDate not supplied

[Inositol in the cerebrospinal fluid in various nervous system diseases].

The authors studied the changes of inositol concentration in the cerebrospinal fluid in 97 neurological patients. The highest values were found in cases of chronic ischalgia or brachial plexus painful syndromes and in multiple sclerosis, and the lowest ones in patients with generalized epileptic seizures. Intermediate values were observed in cases of headaches of different aetiology, in painful spinal syndromes without radiological changes, epidemic vertigo and craniocerebral injuries with brain commotion.

Adolescent↗

PubMedDate not supplied

[The effect of the neck rotation test on auditory evoked brainstem potentials in healthy subjects].

The purpose of the study was to assess the effect of neck rotation test on the pattern of brainstem auditory evoked potentials in healthy subjects. The study was carried out on 40 healthy subjects aged 19-26 years using a Neuromatic 2000 C device of Dantec, by the generally accepted method. The records were taken with the patient in lying position with head in neutral position and during head rotation through 60 degrees to the right and then to the left side. A click stimulus was fed into the tested ear, its frequency was 10 Hz and it was repeated 2000 times. The filters used were 100 Hz-2 kHz. The records obtained during neck rotation showed that the latency times of various waves were slightly prolonged on the side of the rotation (but were still within normal limits), while on the contralateral side they were similar to those in normal position. Moreover, neck rotation to the right or to the left side caused a bilateral slight shortening of the latency time (in absolute values) between waves I-III, at the expense of slight prolongation of this time between waves III-V which was still within the variability range of the normal values.

Acoustic Stimulation↗

PubMedDate not supplied

[The effect of neck rotation on auditory evoked brainstem potentials in patients with degenerative cervical spine changes].

Using the neck rotation test during recording of auditory brainstem evoked potentials the authors examined 60 subjects aged 16-60 years, including 20 healthy ones and 40 with cervical spondylarthrosis. The Neuromatic 2000 C Dantec device was used. Half the patients with cervical spine changes had also receptive hearing damage of low degree. The study demonstrated that neck rotation affected the latency time of the analysed waves I and II. The time was significantly prolonged in the patients with spondylarthrosis. The authors believe that simultaneous prolongation of the mean latency between waves I-III suggests worse compensation of circulation in patients, especially in the initial part of the auditory pathway. The authors think that the neck rotation test could be used in the study of brainstem auditory evoked potentials as a challenge test.

Acoustic Stimulation↗

PubMedDate not supplied

[Diagnosis of the upper thoracic outlet syndrome].

Basing on a review of literature and own experience the authors present the aetiology and various diagnostic methods of thoracic outlet syndrome (t.o.s.), especially electrodiagnostic and Doppler studies. Provocative tests like Wright, Adson or hyperabduction manouvers are discussed and their role in modern diagnosis of t.o.s. is presented.

Electromyography↗

PubMedDate not supplied

[Somatosensory evoked potentials in the assessment of preserved function of long spinal cord pathways versus decisions of operation].

In the light of several presented clinical cases the authors point out the usefulness of somatosensory evoked potentials for the objective determination of the continuity of long pathways in the spinal cord, which in correlation with the clinical findings and results of imaging methods helps in making the decision of surgical intervention. The non-invasiveness of this method makes possible repeated safe control examinations for assessment of the dynamic of lesions in the cord and objective assessment of the neurological condition after operations on the cord.

Adult↗

PubMedDate not supplied

[The physiopathology of acute spinal cord injury and a hope for a successful treatment].

The acute phase of spinal cord injury includes primary and secondary pathological patterns. Primary patterns include the effects of contusion, laceration, stretch of neural tissue and direct vascular trauma. These changes are irreversible. Secondary patterns include posttraumatic ischemic changes, loss of energy metabolism, oedema, release of cytotoxic substances such as free radicals, and electrolyte changes such as an increase in intracellular calcium ions. These changes may be reversible. This determines treatment strategies. Free-radical scavengers, opioid receptor antagonists include TRH and its analogues, calcium channel blockers, volume expander, osmotic diuretics, hypothermia, antioxidants, cycloxygenase inhibitors, serotonin antagonists and NMDA receptor antagonists were tested in experimental models during the last 4 years. The successful treatment should break the feedback loops and trails of secondary injury cascade in many places so combined treatment connected with many elements and surgery decompression is necessary.

Drug Therapy↗

PubMedDate not supplied

[Embolization of AVM's of thoracic spinal cord with histoacryl glue].

The authors present two cases of inoperable AVM's of thoracic spinal cord successfully treated by embolization with histoacryl glue (B. Brown Melsungen AG). The glue used for embolization is characterized by instant polymerization when comes in contact with blood. A mass of polymer is visible on X-ray thanks to contrast medium Lipiodol and metallic powder Tungsten that are added to glue and injected together with the latter. In the first case, a female who presented with paraparesis and walked only with assistance embolization performed in one session resulted in neurological improvement enabling independent walking at follow-up 2 yrs later. In the second case of a young male not walking for severe paraparesis embolization performed in three sessions resulted in significant neurological recovery. 10 days after the first session the patient became ambulatory. 6 months after treatment he presented with mild paraparesis and was still ambulatory and leading independent life. In each case embolization was performed after balloon occlusion test during which the function of spinal cord was monitored by somatosensory evoked potentials and neurological assessment.

Adhesives↗