Fatal rifampicin-ethambutol overdosage.
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Adult↗
Biomedical subjects
J Knepil
Publications and source records attributed to J Knepil.
A short, simple method for the determination of paraquat in plasma.
Paraquat was measured in plasma after precipitation of plasma proteins by addition of a solvent/salt mixture. The paraquat remaining in the supernatant is measured by its free radical formation after addition of alkaline sodium dithionite. The time required for a single determination is approximately 20 minutes.
Diquat↗
Therapeutic comparison of thiol compounds in severe paracetamol poisoning.
Twelve patients with toxic blood concentrations of paracetamol were treated with either cysteamine or amino-acid solution. None of the patients developed severe liver damage, although transient mild biochemical abnormalities developed in three. None of the patients treated with amino-acid solution had side effects due to therapy, whereas all those treated with cysteamine did. It is recommended that amino-acid solutions be used as a temporary measure in patients suspected of massive paracetamol overdose while awaiting estimation of blood paracetamol concentration.
Acetaminophen↗
A sensitive, specific method for measuring N-acetyl-p-aminophenol (paracetamol) in blood.
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Acetaminophen↗