Search PubMed⌕ Search

Biomedical subjects

J Kerr

Publications and source records attributed to J Kerr.

At least 91 records · Page 5Linked to original sources
PubMed1982

Graft rejection in sponges. Genetic structure of accepting and rejecting populations.

Graft rejection frequencies in a population of the sponge Ectyoplasia ferox are reported in relation to the complexity of the histocompatibility system in this species. The frequency of graft acceptance is high but we show that, despite assumptions in the literature to the contrary, this does not imply that sponges accepting each other's grafts are genetically identical. This paper reports that graft-accepting pairs of sponges can have dissimilar plasmalemmal proteins. In addition, a theoretical analysis is presented of the types of histocompatibility systems that would account for the present results and those of others. We concluded that there is no evidence that sponges have highly polymorphic histocompatibility systems. The paper also reports on the histology of graft rejection and discusses some of the ecological relevance of the findings.

Alleles↗
PubMed1980

The families of borderlines. A comparative study.

The families of 12 carefully diagnosed patients with borderline personality disorder are compared with the families of both paranoid schizophrenic patients and patients with neurotic personality disorders. The families of the borderline patients were distinguished by the rigid tightness of the marital bond to the exclusion of the attention, support, or protection of the children. This pattern of neglect conforms to one theme in the clinical literature, and its implications for understanding and treating borderline patients are discussed. Limitations in the research methodology make the conclusions from this study tentative, but the results suggest new areas in need of research attention.

Adolescent↗
PubMed1979

Intracranial compliance during the post-operative period after surgery for intracranial aneurysms.

Generalised post-operative cerebral vasospasm is a major factor in delineating poor operative results following direct ruptured intracranial aneurysms. Continuous monitoring of intracranial pressure seems to be particularly helpful on such occasions, and intracranial compliance determination as well. High intracranial compliance values suggest that even small intracranial volume increases may induce rapid intracranial pressure and situations likely to produce neurological deterioration.

Humans↗
PubMed1978

Optimization of stimuli for trit-anomaloscopy.

Free-choice colour matches were made by 50 young normal trichromats on an anomaloscope. Six equations, of the kind 'blue' + 'green' = 'cyan' + 'yellow', were used in which the stimuli were defined by narrow-band well blocked interference filters. The stimuli were selected so that the instrument controls, which varied the quantities (blue/green), (cyan/yellow) and (cyan + yellow), were nearly independent controls for hue, saturation and brightness respectively. 'Yellow', 'green' and 'cyan' were fixed at 589, 499 and 480 nm, respectively, and the least interindividual variation in blue/green was found for 'blue' in the region 430-439 nm. This and a similar finding in the pilot study of Moreland and Young agree with expectations based on the density spectrum for macular pigment measured by Ruddock. Matches made by a few selected subjects, when the saturation control was locked at a position for the population mean, in the presence of large but typical saturation differences, were the same as when all three controls were used.

Adult↗
PubMed1976

Contrast enhancement of negatively stained macromolecules and biomembranes by single sideband phase contrast interference.

A straightforward procedure is described for the production of contrast enhancement of negatively stained macromolecules and biological membranes by single sideband phase contrast interference (electron optical shadowing). The instrumental adjustment required to produce this type of phase contrast illumination is readily achieved by beam deflection from the strioscopic (dark field) mode. Part of the hollow cone of electrons from the annular condenser aperture that are unscattered by the specimen are permitted to pass through the objective aperture and interfere with the scattered beam. The electron optical shadowing effect is produced because only one side of the unscattered beam is used. Careful adjustment of the beam tilt control, with the ability to tilt in any azimuth, allows optimal illumination conditions to be achieved. The results presented show the increased image contrast obtained using as specimens the purified cylindrical macromolecule from human erythrocyte membranes, purified nuclear envelopes and collagen fibres.

Animals↗