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Biomedical subjects

J Kayser

Publications and source records attributed to J Kayser.

29 records · Page 2Linked to original sources
PubMed1982

Electrocardiographic changes in acute pancreatitis.

Electrograms recorded during 50 episodes of acute pancreatitis were analyzed and compared to those recorded during an asymptomatic period. Ten episodes of acute pancreatitis occurred in eight patients with normal ECGs during an asymptomatic period. Nonspecific ST-T changes were recorded in only two of them (one with mild hypokalemia). ECGs recorded during 40 episodes of acute pancreatitis in 24 patients who had ECG abnormalities during an asymptomatic period revealed no significant changes during 33 of the episodes. The seven episodes associated with significant ECG changes occurred in patients with previous ECG abnormalities. Review of the literature and of our cases strongly suggests that significant ECG alterations during acute pancreatitis usually occur in patients with previous cardiac abnormalities.

Acute Disease↗
PubMed1979

[Vitamin D and reproduction in Wistar rats].

Females have received from weaning a semi-synthetic diet (0,35% Ca; 0,32% P; 0,03% Mg), with or without vitamin D (+/- D). Fertility of these females was not changed. At weaning, the young from mothers--D had lower weight, calcemia and phosphatemia, but the ash content of the femur was the same as for young from mothers + D. Young rats from mothers +/- D were given the diet with or without vitamin D. 19 days after weaning, the diet of the mother (+/- D) appears to be the principal factor for growth, calcemia and the ash content of the femur; the diet of the young (+/- D) produced only slight differences between ash contents.

Animals↗
PubMed1978

[Growth and longevity of Wistar rats receiving a diet whose protein content is rapidly lowered in relation to aging].

Growth and longevity of the Rats were the same when: (i) the diet was rich in casein (21%), from weaning to death: (ii) the casein content of this diet (without B12) was progressively lowered from weaning to 200 days of age, and thereafter was 7%. When the casein level had been too rapidly lowered, inducing retardation of growth after 75 days, maximal growth was lowered and life span was increased.

Aging↗
PubMedDate not supplied

Postmenopausal hormonal support: discontinuation of raloxifene versus estrogen.

OBJECTIVE: To determine possible differences in continuation among women initiating treatment with the selective estrogen receptor modulator raloxifene, versus those initiating treatment with estrogen-containing regimens. DESIGN: A pharmacy prescription database search for refill patterns. The study subjects were members of Kaiser Foundation Health Plan, a large health maintenance organization; 1,394 women age >or=60 years who filled index prescriptions for either raloxifene (n = 331) or systemic estrogens (n = 1,063) between April 1998 and March 1999. The main outcome measure was discontinuation based on prescription refill patterns through December 2000. RESULTS: At 24 months, the probabilities of discontinuing were 56% for women starting raloxifene compared to 72% for women starting estrogens. The likelihood of discontinuation was significantly less among women starting raloxifene than among those starting estrogen (hazard ratio = 0.75; 95% confidence interval = 0.64-0.88). Adjustments for age and prescriber specialty did not affect the risk. CONCLUSIONS: We conclude that discontinuation of estrogen by women well beyond the age of menopause is high; more than two-thirds discontinue within 2 years of starting. Women starting therapy with raloxifene are 25% percent less likely to discontinue their medication than those starting estrogen, providing some promise that long-term benefits of raloxifene may be more easily achieved than those of estrogen.

Aged↗